Conservation of cofitness between OKFHMN_20250 and OKFHMN_13400 in Escherichia coli ECRC100

32 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli ECRC100 1.0 OKFHMN_20250 relA GTP diphosphokinase 1.0 OKFHMN_13400 thiH 2-iminoacetate synthase ThiH 0.75 18
Escherichia coli ECOR38 1.00 HEPCGN_19500 relA GTP diphosphokinase 0.99 HEPCGN_12035 thiH 2-iminoacetate synthase ThiH low > 87
Escherichia coli BL21 1.00 ECD_02629 (p)ppGpp synthetase I/GTP pyrophosphokinase 0.99 ECD_03866 tyrosine lyase, involved in thiamine-thiazole moiety synthesis low > 61
Escherichia coli ECRC101 1.00 MCAODC_10775 relA GTP diphosphokinase 1.00 MCAODC_03900 thiH 2-iminoacetate synthase ThiH low > 87
Escherichia coli ECRC102 1.00 NIAGMN_18020 relA GTP diphosphokinase 1.00 NIAGMN_11150 thiH 2-iminoacetate synthase ThiH — —
Escherichia coli BW25113 1.00 b2784 relA (p)ppGpp synthetase I/GTP pyrophosphokinase (NCBI) 0.99 b3990 thiH thiamine biosynthesis protein ThiH (NCBI) low > 76
Escherichia coli ECRC98 1.00 JDDGAC_23915 relA GTP diphosphokinase 1.00 JDDGAC_17025 thiH 2-iminoacetate synthase ThiH low > 86
Escherichia coli ECRC99 1.00 KEDOAH_07880 relA GTP diphosphokinase 1.00 KEDOAH_14760 thiH 2-iminoacetate synthase ThiH — —
Escherichia coli ECOR27 1.00 NOLOHH_12125 relA GTP diphosphokinase 0.99 NOLOHH_05545 thiH 2-iminoacetate synthase ThiH low > 75
Escherichia coli Nissle 1917 1.00 ECOLIN_RS15515 GTP diphosphokinase 0.97 ECOLIN_RS23015 2-iminoacetate synthase ThiH low > 55
Escherichia coli ECRC62 1.00 BNILDI_10630 relA GTP diphosphokinase 1.00 BNILDI_05980 thiH 2-iminoacetate synthase ThiH low > 75
Escherichia fergusonii Becca 1.00 EFB2_01133 GTP pyrophosphokinase 0.98 EFB2_04622 2-iminoacetate synthase low > 86
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_00947 GTP pyrophosphokinase 0.99 OHPLBJKB_04061 2-iminoacetate synthase low > 73
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.96 GFF4837 'GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2)' transl_table=11 0.92 GFF4203 Thiazole biosynthesis protein ThiH low > 78
Klebsiella michiganensis M5al 0.94 BWI76_RS22805 GTP diphosphokinase 0.91 BWI76_RS01530 2-iminoacetate synthase ThiH low > 92
Enterobacter asburiae PDN3 0.94 EX28DRAFT_2864 (p)ppGpp synthetase, RelA/SpoT family 0.90 EX28DRAFT_4531 thiazole biosynthesis protein ThiH low > 76
Enterobacter sp. TBS_079 0.93 MPMX20_03653 GTP pyrophosphokinase 0.91 MPMX20_00212 2-iminoacetate synthase low > 85
Dickeya dadantii 3937 0.87 DDA3937_RS17015 GTP diphosphokinase 0.81 DDA3937_RS01150 2-iminoacetate synthase ThiH low > 74
Dickeya dianthicola 67-19 0.87 HGI48_RS17070 GTP diphosphokinase 0.82 HGI48_RS01145 2-iminoacetate synthase ThiH low > 71
Dickeya dianthicola ME23 0.87 DZA65_RS18145 GTP diphosphokinase 0.81 DZA65_RS01190 2-iminoacetate synthase ThiH low > 75
Pectobacterium carotovorum WPP14 0.86 HER17_RS04115 GTP diphosphokinase 0.82 HER17_RS20405 2-iminoacetate synthase ThiH low > 75
Erwinia tracheiphila SCR3 0.86 LU632_RS06350 relA GTP diphosphokinase 0.77 LU632_RS00945 thiH 2-iminoacetate synthase ThiH low > 74
Serratia liquefaciens MT49 0.85 IAI46_03600 GTP diphosphokinase 0.79 IAI46_01295 2-iminoacetate synthase ThiH low > 86
Rahnella sp. WP5 0.85 EX31_RS07955 GTP diphosphokinase 0.77 EX31_RS16790 2-iminoacetate synthase ThiH low > 89
Vibrio cholerae E7946 ATCC 55056 0.67 CSW01_12405 GTP diphosphokinase 0.63 CSW01_00360 2-iminoacetate synthase ThiH low > 62
Shewanella sp. ANA-3 0.59 Shewana3_1111 (p)ppGpp synthetase I, SpoT/RelA (RefSeq) 0.54 Shewana3_1941 thiH thiamine biosynthesis protein ThiH (RefSeq) low > 73
Shewanella amazonensis SB2B 0.58 Sama_1033 GTP diphosphokinase (RefSeq) 0.55 Sama_1855 thiH thiamine biosynthesis protein ThiH (RefSeq) low > 62
Shewanella oneidensis MR-1 0.58 SO3455 relA GTP pyrophosphokinase (NCBI ptt file) 0.54 SO2440 thiH thiH protein (NCBI ptt file) low > 76
Shewanella loihica PV-4 0.58 Shew_1202 (p)ppGpp synthetase I, SpoT/RelA (RefSeq) 0.51 Shew_2091 thiH thiamine biosynthesis protein ThiH (RefSeq) low > 60
Alteromonas macleodii MIT1002 0.53 MIT1002_00794 GTP pyrophosphokinase 0.55 MIT1002_00092 2-iminoacetate synthase low > 70
Bacteroides ovatus ATCC 8483 0.24 BACOVA_02404 RelA/SpoT family protein 0.45 BACOVA_02357 thiazole biosynthesis protein ThiH low > 94
Bacteroides thetaiotaomicron VPI-5482 0.24 BT0700 GTP pyrophosphokinase (NCBI ptt file) 0.45 BT0649 thiamine biosynthesis protein ThiH (NCBI ptt file) low > 81
Bacteroides stercoris CC31F 0.23 HMPREF1181_RS16240 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase 0.47 HMPREF1181_RS14690 2-iminoacetate synthase ThiH low > 56

Not shown: 39 genomes with orthologs for OKFHMN_20250 only; 8 genomes with orthologs for OKFHMN_13400 only