Conservation of cofitness between NOLOHH_17430 and NOLOHH_22205 in Escherichia coli ECOR27

33 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli ECOR27 1.0 NOLOHH_17430 astD succinylglutamate-semialdehyde dehydrogenase 1.0 NOLOHH_22205 macA macrolide transporter subunit MacA 0.61 18
Escherichia coli ECRC62 0.99 BNILDI_16215 astD succinylglutamate-semialdehyde dehydrogenase 1.00 BNILDI_20460 macA macrolide transporter subunit MacA low > 75
Escherichia coli HS(pFamp)R (ATCC 700891) 0.99 OHPLBJKB_01986 N-succinylglutamate 5-semialdehyde dehydrogenase 1.00 OHPLBJKB_02790 Macrolide export protein MacA low > 73
Escherichia coli BL21 0.99 ECD_01715 succinylglutamic semialdehyde dehydrogenase 1.00 ECD_00883 macrolide transporter membrane fusion protein (MFP) component — —
Escherichia coli ECRC100 0.97 OKFHMN_26915 astD succinylglutamate-semialdehyde dehydrogenase 1.00 OKFHMN_05810 macA macrolide transporter subunit MacA low > 80
Escherichia coli ECRC102 0.97 NIAGMN_01150 astD succinylglutamate-semialdehyde dehydrogenase 1.00 NIAGMN_03850 macA macrolide transporter subunit MacA — —
Escherichia coli ECRC98 0.97 JDDGAC_01490 astD succinylglutamate-semialdehyde dehydrogenase 1.00 JDDGAC_09445 macA macrolide transporter subunit MacA low > 86
Escherichia coli ECRC99 0.97 KEDOAH_01195 astD succinylglutamate-semialdehyde dehydrogenase 1.00 KEDOAH_22100 macA macrolide transporter subunit MacA — —
Escherichia coli ECRC101 0.97 MCAODC_18495 astD succinylglutamate-semialdehyde dehydrogenase 1.00 MCAODC_25025 macA macrolide transporter subunit MacA low > 87
Escherichia coli BW25113 0.97 b1746 astD succinylglutamic semialdehyde dehydrogenase (NCBI) 1.00 b0878 b0878 putative membrane protein (VIMSS) low > 76
Escherichia coli ECOR38 0.96 HEPCGN_05280 astD succinylglutamate-semialdehyde dehydrogenase 1.00 HEPCGN_22875 macA macrolide transporter subunit MacA low > 87
Escherichia fergusonii Becca 0.96 EFB2_02247 N-succinylglutamate 5-semialdehyde dehydrogenase 0.99 EFB2_03183 Macrolide export protein MacA low > 86
Escherichia coli Nissle 1917 0.95 ECOLIN_RS09735 succinylglutamate-semialdehyde dehydrogenase 1.00 ECOLIN_RS04675 macrolide transporter subunit MacA — —
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.82 GFF3494 Succinylglutamic semialdehyde dehydrogenase (EC 1.2.1.71) 0.86 GFF4905 Macrolide-specific efflux protein MacA low > 78
Enterobacter asburiae PDN3 0.81 EX28DRAFT_1750 succinylglutamic semialdehyde dehydrogenase (EC 1.2.1.71) 0.82 EX28DRAFT_2054 RND family efflux transporter, MFP subunit low > 76
Enterobacter sp. TBS_079 0.79 MPMX20_01867 N-succinylglutamate 5-semialdehyde dehydrogenase 0.85 MPMX20_01540 Macrolide export protein MacA low > 85
Klebsiella michiganensis M5al 0.76 BWI76_RS11680 succinylglutamate-semialdehyde dehydrogenase 0.80 BWI76_RS09595 macrolide transporter subunit MacA low > 92
Acinetobacter radioresistens SK82 0.69 MPMX26_02249 N-succinylglutamate 5-semialdehyde dehydrogenase 0.33 MPMX26_00467 Macrolide export protein MacA low > 36
Serratia liquefaciens MT49 0.65 IAI46_15325 succinylglutamate-semialdehyde dehydrogenase 0.62 IAI46_08495 macrolide transporter subunit MacA low > 86
Shewanella oneidensis MR-1 0.57 SO0619 astD Succinylglutamic semialdehyde dehydrogenase (EC 1.2.1.71) (from data) 0.32 SO0820 HlyD family secretion protein (NCBI ptt file) low > 76
Pseudomonas simiae WCS417 0.57 PS417_21695 succinylglutamate-semialdehyde dehydrogenase 0.30 PS417_17635 hemolysin secretion protein D low > 88
Pseudomonas fluorescens FW300-N2C3 0.57 AO356_18740 succinylglutamate-semialdehyde dehydrogenase 0.40 AO356_28205 hemolysin secretion protein D low > 104
Pseudomonas fluorescens FW300-N2E2 0.57 Pf6N2E2_5668 Succinylglutamic semialdehyde dehydrogenase (EC 1.2.1.71) 0.29 Pf6N2E2_20 pyoverdine-specific efflux macA-like protein low > 103
Pseudomonas fluorescens FW300-N1B4 0.57 Pf1N1B4_3444 Succinylglutamic semialdehyde dehydrogenase (EC 1.2.1.71) 0.30 Pf1N1B4_134 pyoverdine-specific efflux macA-like protein — —
Shewanella sp. ANA-3 0.57 Shewana3_0612 astD succinylglutamic semialdehyde dehydrogenase (RefSeq) 0.31 Shewana3_3456 RND family efflux transporter MFP subunit (RefSeq) low > 73
Pseudomonas sp. RS175 0.57 PFR28_03280 N-succinylglutamate 5-semialdehyde dehydrogenase 0.40 PFR28_02258 Macrolide export protein MacA — —
Pseudomonas fluorescens GW456-L13 0.57 PfGW456L13_1974 Succinylglutamic semialdehyde dehydrogenase (EC 1.2.1.71) (from data) 0.29 PfGW456L13_2393 pyoverdine-specific efflux macA-like protein low > 87
Pseudomonas syringae pv. syringae B728a ΔmexB 0.57 Psyr_3562 succinylglutamic semialdehyde dehydrogenase 0.42 Psyr_2617 Secretion protein HlyD low > 86
Pseudomonas syringae pv. syringae B728a 0.57 Psyr_3562 succinylglutamic semialdehyde dehydrogenase 0.42 Psyr_2617 Secretion protein HlyD low > 86
Pseudomonas fluorescens SBW25-INTG 0.56 PFLU_RS23300 succinylglutamate-semialdehyde dehydrogenase 0.39 PFLU_RS12495 macrolide transporter subunit MacA low > 109
Pseudomonas fluorescens SBW25 0.56 PFLU_RS23300 succinylglutamate-semialdehyde dehydrogenase 0.39 PFLU_RS12495 macrolide transporter subunit MacA low > 109
Pseudomonas putida KT2440 0.56 PP_4478 N-succinylglutamate 5-semialdehyde dehydrogenase 0.28 PP_4209 ABC export system, membrane fusion protein low > 96
Paraburkholderia sabiae LMG 24235 0.53 QEN71_RS23360 succinylglutamate-semialdehyde dehydrogenase 0.40 QEN71_RS35170 macrolide transporter subunit MacA — —
Kangiella aquimarina DSM 16071 0.51 B158DRAFT_2219 succinylglutamic semialdehyde dehydrogenase (EC 1.2.1.71) 0.14 B158DRAFT_0948 RND family efflux transporter, MFP subunit low > 40

Not shown: 16 genomes with orthologs for NOLOHH_17430 only; 26 genomes with orthologs for NOLOHH_22205 only