Conservation of cofitness between NOLOHH_15540 and NOLOHH_06470 in Escherichia coli ECOR27

33 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli ECOR27 1.0 NOLOHH_15540 mdtB multidrug efflux RND transporter permease subunit MdtB 1.0 NOLOHH_06470 yigL sugar/pyridoxal phosphate phosphatase YigL 0.57 15
Escherichia coli ECRC99 1.00 KEDOAH_03955 mdtB multidrug efflux RND transporter permease subunit MdtB 1.00 KEDOAH_13810 yigL sugar/pyridoxal phosphate phosphatase YigL — —
Escherichia coli ECRC102 1.00 NIAGMN_22140 mdtB multidrug efflux RND transporter permease subunit MdtB 0.99 NIAGMN_12095 yigL sugar/pyridoxal phosphate phosphatase YigL — —
Escherichia coli ECRC101 1.00 MCAODC_20745 mdtB multidrug efflux RND transporter permease subunit MdtB 1.00 MCAODC_04845 yigL sugar/pyridoxal phosphate phosphatase YigL low > 87
Escherichia coli ECRC98 1.00 JDDGAC_28305 mdtB multidrug efflux RND transporter permease subunit MdtB 1.00 JDDGAC_17965 yigL sugar/pyridoxal phosphate phosphatase YigL low > 86
Escherichia coli ECRC100 1.00 OKFHMN_24195 mdtB multidrug efflux RND transporter permease subunit MdtB 0.99 OKFHMN_14340 yigL sugar/pyridoxal phosphate phosphatase YigL low > 80
Escherichia coli Nissle 1917 1.00 ECOLIN_RS12200 multidrug efflux RND transporter permease subunit MdtB 0.99 ECOLIN_RS21965 sugar/pyridoxal phosphate phosphatase YigL — —
Escherichia coli BW25113 1.00 b2075 mdtB multidrug efflux system, subunit B (NCBI) 0.99 b3826 yigL predicted hydrolase (NCBI) low > 76
Escherichia fergusonii Becca 1.00 EFB2_01780 Multidrug resistance protein MdtB 0.99 EFB2_04811 Pyridoxal phosphate phosphatase YigL low > 86
Escherichia coli ECRC62 1.00 BNILDI_14455 mdtB multidrug efflux RND transporter permease subunit MdtB 1.00 BNILDI_05060 yigL sugar/pyridoxal phosphate phosphatase YigL low > 75
Escherichia coli BL21 1.00 ECD_01980 multidrug efflux system, subunit B 1.00 ECD_03705 pyridoxal phosphate phosphatase low > 61
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_01629 Multidrug resistance protein MdtB 0.99 OHPLBJKB_04225 Pyridoxal phosphate phosphatase YigL low > 73
Escherichia coli ECOR38 1.00 HEPCGN_02885 mdtB multidrug efflux RND transporter permease subunit MdtB 1.00 HEPCGN_13040 yigL sugar/pyridoxal phosphate phosphatase YigL low > 87
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.91 GFF3854 Multidrug transporter MdtB 0.91 GFF252 Cof protein, HD superfamily hydrolase low > 78
Klebsiella michiganensis M5al 0.90 BWI76_RS19255 multidrug transporter subunit MdtB 0.88 BWI76_RS01265 sugar/pyridoxal phosphate phosphatase YigL low > 92
Enterobacter sp. TBS_079 0.90 MPMX20_03061 Multidrug resistance protein MdtB 0.93 MPMX20_04454 Pyridoxal phosphate phosphatase YigL low > 85
Enterobacter asburiae PDN3 0.90 EX28DRAFT_0483 Cation/multidrug efflux pump 0.93 EX28DRAFT_4491 HAD-superfamily hydrolase, subfamily IIB low > 76
Serratia liquefaciens MT49 0.81 IAI46_18975 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.78 IAI46_00790 sugar/pyridoxal phosphate phosphatase YigL low > 86
Pantoea sp. MT58 0.81 IAI47_06870 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.72 IAI47_18335 sugar/pyridoxal phosphate phosphatase YigL low > 76
Erwinia tracheiphila SCR3 0.80 LU632_RS08690 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.72 LU632_RS24075 yigL sugar/pyridoxal phosphate phosphatase YigL low > 74
Pectobacterium carotovorum WPP14 0.79 HER17_RS06320 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.81 HER17_RS01415 sugar/pyridoxal phosphate phosphatase YigL low > 75
Dickeya dadantii 3937 0.77 DDA3937_RS15265 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.76 DDA3937_RS19825 sugar/pyridoxal phosphate phosphatase YigL low > 74
Dickeya dianthicola ME23 0.77 DZA65_RS16165 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.76 DZA65_RS21025 sugar/pyridoxal phosphate phosphatase YigL low > 75
Dickeya dianthicola 67-19 0.76 HGI48_RS15345 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.77 HGI48_RS19980 sugar/pyridoxal phosphate phosphatase YigL low > 71
Pseudomonas sp. RS175 0.63 PFR28_02194 Multidrug resistance protein MdtB 0.18 PFR28_01675 Sugar phosphatase YidA low > 88
Rahnella sp. WP5 0.62 EX31_RS13380 MMPL family transporter 0.78 EX31_RS15230 sugar/pyridoxal phosphate phosphatase YigL low > 89
Pseudomonas fluorescens FW300-N2E2 0.62 Pf6N2E2_1272 Acriflavin resistance plasma membrane protein 0.16 Pf6N2E2_759 HMP-PP hydrolase (pyridoxal phosphatase) Cof, detected in genetic screen for thiamin metabolic genes (PMID:15292217) low > 103
Pseudomonas fluorescens SBW25 0.61 PFLU_RS13430 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.18 PFLU_RS13145 Cof-type HAD-IIB family hydrolase 0.40 96
Pseudomonas fluorescens SBW25-INTG 0.61 PFLU_RS13430 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.18 PFLU_RS13145 Cof-type HAD-IIB family hydrolase low > 109
Pseudomonas simiae WCS417 0.61 PS417_12745 multidrug transporter 0.18 PS417_12455 hydrolase low > 88
Paraburkholderia sabiae LMG 24235 0.60 QEN71_RS23305 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.36 QEN71_RS29060 Cof-type HAD-IIB family hydrolase low > 153
Paraburkholderia bryophila 376MFSha3.1 0.59 H281DRAFT_06492 multidrug efflux pump 0.35 H281DRAFT_05732 hypothetical protein low > 103
Burkholderia phytofirmans PsJN 0.58 BPHYT_RS07785 multidrug transporter 0.33 BPHYT_RS19055 COF family hydrolase low > 109
Paraburkholderia graminis OAS925 0.58 ABIE53_001783 multidrug efflux pump 0.35 ABIE53_000135 Cof subfamily protein (haloacid dehalogenase superfamily) low > 113

Not shown: 33 genomes with orthologs for NOLOHH_15540 only; 3 genomes with orthologs for NOLOHH_06470 only