Conservation of cofitness between HER17_RS16505 and HER17_RS12260 in Pectobacterium carotovorum WPP14

31 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Pectobacterium carotovorum WPP14 1.0 HER17_RS16505 amino-acid N-acetyltransferase 1.0 HER17_RS12260 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.80 9
Dickeya dianthicola 67-19 0.91 HGI48_RS05000 amino-acid N-acetyltransferase 0.89 HGI48_RS09715 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE low > 71
Dickeya dianthicola ME23 0.91 DZA65_RS05340 amino-acid N-acetyltransferase 0.89 DZA65_RS10025 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.88 10
Dickeya dadantii 3937 0.90 DDA3937_RS04990 amino-acid N-acetyltransferase 0.90 DDA3937_RS09705 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.86 21
Serratia liquefaciens MT49 0.89 IAI46_20395 amino-acid N-acetyltransferase 0.81 IAI46_08180 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE low > 86
Enterobacter sp. TBS_079 0.89 MPMX20_03681 Amino-acid acetyltransferase 0.85 MPMX20_03008 Histidine biosynthesis bifunctional protein HisIE 0.89 29
Enterobacter asburiae PDN3 0.88 EX28DRAFT_2893 N-acetylglutamate synthase (EC 2.3.1.1) 0.84 EX28DRAFT_0533 phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19)/phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) 0.85 6
Rahnella sp. WP5 0.88 EX31_RS13160 amino-acid N-acetyltransferase 0.74 EX31_RS11470 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.95 38
Escherichia coli BW25113 0.87 b2818 argA N-acetylglutamate synthase (NCBI) 0.82 b2026 hisI bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein (NCBI) 0.87 25
Escherichia coli ECOR38 0.87 HEPCGN_19315 argA amino-acid N-acetyltransferase 0.81 HEPCGN_03190 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.92 35
Escherichia coli ECRC99 0.87 KEDOAH_08070 argA amino-acid N-acetyltransferase 0.75 KEDOAH_03665 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE — —
Escherichia fergusonii Becca 0.87 EFB2_01066 Amino-acid acetyltransferase 0.75 EFB2_01830 Histidine biosynthesis bifunctional protein HisIE low > 86
Escherichia coli BL21 0.87 ECD_02666 amino acid N-acetyltransferase and inactive acetylglutamate kinase 0.82 ECD_01928 phosphoribosyl-AMP cyclohydrolase and phosphoribosyl-ATP pyrophosphatase low > 61
Escherichia coli ECRC100 0.87 OKFHMN_20060 argA amino-acid N-acetyltransferase 0.75 OKFHMN_24485 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.96 36
Escherichia coli ECRC62 0.87 BNILDI_10425 argA amino-acid N-acetyltransferase 0.80 BNILDI_14710 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.94 40
Escherichia coli Nissle 1917 0.87 ECOLIN_RS15820 amino-acid N-acetyltransferase 0.75 ECOLIN_RS11975 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE — —
Escherichia coli ECRC102 0.87 NIAGMN_17830 argA amino-acid N-acetyltransferase 0.75 NIAGMN_22430 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE — —
Escherichia coli HS(pFamp)R (ATCC 700891) 0.87 OHPLBJKB_00912 Amino-acid acetyltransferase 0.81 OHPLBJKB_01674 Histidine biosynthesis bifunctional protein HisIE low > 73
Escherichia coli ECRC98 0.87 JDDGAC_23725 argA amino-acid N-acetyltransferase 0.75 JDDGAC_28595 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE low > 86
Escherichia coli ECOR27 0.87 NOLOHH_11945 argA amino-acid N-acetyltransferase 0.76 NOLOHH_15800 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.81 55
Escherichia coli ECRC101 0.87 MCAODC_10585 argA amino-acid N-acetyltransferase 0.75 MCAODC_20455 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.87 41
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.87 GFF1299 N-acetylglutamate synthase (EC 2.3.1.1) 0.74 GFF3906 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) / Phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) low > 78
Klebsiella michiganensis M5al 0.86 BWI76_RS23220 amino-acid N-acetyltransferase 0.83 BWI76_RS18955 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase 0.87 31
Pantoea sp. MT58 0.86 IAI47_03975 amino-acid N-acetyltransferase 0.82 IAI47_07060 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.85 20
Erwinia tracheiphila SCR3 0.85 LU632_RS06210 argA amino-acid N-acetyltransferase 0.79 LU632_RS08915 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.84 5
Shewanella oneidensis MR-1 0.67 SO4245 argA amino-acid acetyltransferase (NCBI ptt file) 0.61 SO2067 hisI phosphoribosyl-ATP pyrophosphatase/phosphoribosyl-AMP cyclohydrolase (NCBI ptt file) 0.89 40
Shewanella sp. ANA-3 0.67 Shewana3_3767 N-acetylglutamate synthase (RefSeq) 0.60 Shewana3_1847 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein (RefSeq) 0.87 40
Shewanella amazonensis SB2B 0.67 Sama_0330 N-acetylglutamate synthase (RefSeq) 0.58 Sama_1948 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein (RefSeq) 0.92 22
Vibrio cholerae E7946 ATCC 55056 0.66 CSW01_11765 amino-acid N-acetyltransferase 0.64 CSW01_05780 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase low > 62
Shewanella loihica PV-4 0.65 Shew_3478 N-acetylglutamate synthase (RefSeq) 0.59 Shew_2204 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein (RefSeq) 0.95 30
Alteromonas macleodii MIT1002 0.49 MIT1002_00466 Amino-acid acetyltransferase 0.63 MIT1002_02639 Phosphoribosyl-ATP pyrophosphatase 0.94 46
Acinetobacter radioresistens SK82 0.48 MPMX26_00029 Amino-acid acetyltransferase 0.34 MPMX26_00264 Histidine biosynthesis bifunctional protein HisIE 0.84 26

Not shown: 32 genomes with orthologs for HER17_RS16505 only; 18 genomes with orthologs for HER17_RS12260 only