Conservation of cofitness between GFF119 and GFF2469 in Hydrogenophaga sp. GW460-11-11-14-LB1

15 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Hydrogenophaga sp. GW460-11-11-14-LB1 1.0 GFF119 Uncharacterized protein EC-HemY, likely associated with heme metabolism based on gene clustering with hemC, hemD in Proteobacteria (unrelated to HemY-type PPO in GramPositives) 1.0 GFF2469 NADP-dependent malic enzyme (EC 1.1.1.40) 0.71 19
Variovorax sp. OAS795 0.40 ABID97_RS08240 heme biosynthesis HemY N-terminal domain-containing protein 0.85 ABID97_RS02510 NADP-dependent malic enzyme low > 91
Acidovorax sp. GW101-3H11 0.39 Ac3H11_3549 Uncharacterized protein EC-HemY, likely associated with heme metabolism based on gene clustering with hemC, hemD in Proteobacteria (unrelated to HemY-type PPO in GramPositives) 0.85 Ac3H11_4331 NADP-dependent malic enzyme (EC 1.1.1.40) 0.41 67
Variovorax sp. SCN45 0.33 GFF3842 Uncharacterized protein EC-HemY in Proteobacteria (unrelated to HemY-type PPO in GramPositives) 0.86 GFF3248 NADP-dependent malic enzyme (EC 1.1.1.40) low > 127
Burkholderia phytofirmans PsJN 0.15 BPHYT_RS05240 heme biosynthesis protein HemY 0.68 BPHYT_RS16880 malic enzyme — —
Paraburkholderia sabiae LMG 24235 0.15 QEN71_RS24940 heme biosynthesis protein HemY 0.71 QEN71_RS27040 NADP-dependent malic enzyme — —
Herbaspirillum seropedicae SmR1 0.15 HSERO_RS14650 porphyrin biosynthesis protein 0.70 HSERO_RS16825 NADP-dependent malic enzyme oxidoreductase — —
Paraburkholderia bryophila 376MFSha3.1 0.14 H281DRAFT_00200 HemY protein 0.68 H281DRAFT_06308 malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+) — —
Paraburkholderia graminis OAS925 0.14 ABIE53_001317 HemY protein 0.68 ABIE53_003543 malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+) low > 113
Ralstonia sp. UNC404CL21Col 0.14 ABZR87_RS16125 heme biosynthesis protein HemY 0.71 ABZR87_RS01565 NADP-dependent malic enzyme low > 80
Ralstonia solanacearum UW163 0.14 UW163_RS09435 heme biosynthesis protein HemY 0.71 UW163_RS07725 NADP-dependent malic enzyme — —
Ralstonia solanacearum IBSBF1503 0.14 RALBFv3_RS04235 heme biosynthesis protein HemY 0.71 RALBFv3_RS05900 NADP-dependent malic enzyme low > 76
Ralstonia solanacearum PSI07 0.13 RPSI07_RS13115 heme biosynthesis protein HemY 0.71 RPSI07_RS11345 NADP-dependent malic enzyme low > 81
Cupriavidus basilensis FW507-4G11 0.12 RR42_RS15890 heme biosynthesis protein HemY 0.67 RR42_RS17610 malate dehydrogenase low > 128
Ralstonia solanacearum GMI1000 0.12 RS_RS11825 heme biosynthesis protein HemY 0.71 RS_RS13845 NADP-dependent malic enzyme low > 80
Dechlorosoma suillum PS 0.10 Dsui_1599 putative enzyme of heme biosynthesis 0.63 Dsui_0130 malic enzyme low > 51

Not shown: 0 genomes with orthologs for GFF119 only; 13 genomes with orthologs for GFF2469 only