Conservation of cofitness between BWI76_RS19845 and BWI76_RS25220 in Klebsiella michiganensis M5al

29 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Klebsiella michiganensis M5al 1.0 BWI76_RS19845 phosphatase 1.0 BWI76_RS25220 outer membrane lipid asymmetry maintenance protein MlaD 0.59 5
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.84 GFF3747 FIG001881: hydrolase of alkaline phosphatase superfamily 0.81 GFF2937 Uncharacterized ABC transporter, periplasmic component YrbD low > 78
Escherichia coli ECRC102 0.83 NIAGMN_21100 yejM LPS biosynthesis-modulating metalloenzyme YejM 0.81 NIAGMN_15745 mlaD outer membrane lipid asymmetry maintenance protein MlaD — —
Escherichia coli BL21 0.83 ECD_02118 essential inner membrane DUF3413 domain-containing protein; lipid A production and membrane permeability factor 0.81 ECD_03058 OM lipid asymmetry maintenance protein; membrane-anchored ABC family periplasmic binding protein low > 61
Escherichia coli ECRC100 0.83 OKFHMN_23335 yejM LPS biosynthesis-modulating metalloenzyme YejM 0.81 OKFHMN_17985 mlaD outer membrane lipid asymmetry maintenance protein MlaD low > 80
Escherichia coli ECRC99 0.83 KEDOAH_04850 yejM LPS biosynthesis-modulating metalloenzyme YejM 0.81 KEDOAH_10165 mlaD outer membrane lipid asymmetry maintenance protein MlaD — —
Escherichia coli ECOR38 0.83 HEPCGN_22600 yejM LPS biosynthesis-modulating metalloenzyme YejM 0.81 HEPCGN_16860 mlaD outer membrane lipid asymmetry maintenance protein MlaD low > 87
Enterobacter asburiae PDN3 0.83 EX28DRAFT_0373 Predicted hydrolase of alkaline phosphatase superfamily 0.77 EX28DRAFT_3247 mce related protein low > 76
Escherichia coli ECRC98 0.83 JDDGAC_27295 yejM LPS biosynthesis-modulating metalloenzyme YejM 0.81 JDDGAC_21610 mlaD outer membrane lipid asymmetry maintenance protein MlaD low > 86
Escherichia fergusonii Becca 0.83 EFB2_01668 Inner membrane protein YejM 0.81 EFB2_00630 Intermembrane phospholipid transport system binding protein MlaD low > 86
Escherichia coli ECRC101 0.83 MCAODC_14385 yejM LPS biosynthesis-modulating metalloenzyme YejM 0.81 MCAODC_08505 mlaD outer membrane lipid asymmetry maintenance protein MlaD low > 87
Escherichia coli Nissle 1917 0.83 ECOLIN_RS12785 LPS biosynthesis-modulating metalloenzyme YejM 0.80 ECOLIN_RS18380 outer membrane lipid asymmetry maintenance protein MlaD — —
Escherichia coli HS(pFamp)R (ATCC 700891) 0.83 OHPLBJKB_01521 Inner membrane protein YejM 0.81 OHPLBJKB_00507 putative phospholipid ABC transporter-binding protein MlaD low > 73
Escherichia coli BW25113 0.83 b2188 yejM predicted hydrolase, inner membrane (NCBI) 0.81 b3193 yrbD predicted ABC-type organic solvent transporter (NCBI) low > 76
Escherichia coli ECOR27 0.83 NOLOHH_14910 yejM LPS biosynthesis-modulating metalloenzyme YejM 0.81 NOLOHH_09785 mlaD outer membrane lipid asymmetry maintenance protein MlaD low > 75
Escherichia coli ECRC62 0.83 BNILDI_13830 yejM LPS biosynthesis-modulating metalloenzyme YejM 0.81 BNILDI_01750 mlaD outer membrane lipid asymmetry maintenance protein MlaD low > 75
Enterobacter sp. TBS_079 0.82 MPMX20_03154 Inner membrane protein YejM 0.76 MPMX20_04099 Intermembrane phospholipid transport system binding protein MlaD low > 85
Erwinia tracheiphila SCR3 0.66 LU632_RS17620 yejM LPS biosynthesis-modulating metalloenzyme YejM 0.59 LU632_RS21235 mlaD outer membrane lipid asymmetry maintenance protein MlaD — —
Pantoea sp. MT58 0.66 IAI47_06560 DUF3413 domain-containing protein 0.65 IAI47_17135 outer membrane lipid asymmetry maintenance protein MlaD low > 76
Rahnella sp. WP5 0.63 EX31_RS19220 DUF3413 domain-containing protein 0.64 EX31_RS12445 outer membrane lipid asymmetry maintenance protein MlaD low > 89
Serratia liquefaciens MT49 0.63 IAI46_17370 DUF3413 domain-containing protein 0.73 IAI46_22420 outer membrane lipid asymmetry maintenance protein MlaD low > 86
Dickeya dadantii 3937 0.62 DDA3937_RS09115 DUF3413 domain-containing protein 0.73 DDA3937_RS01575 outer membrane lipid asymmetry maintenance protein MlaD low > 74
Dickeya dianthicola 67-19 0.62 HGI48_RS09155 DUF3413 domain-containing protein 0.72 HGI48_RS01490 outer membrane lipid asymmetry maintenance protein MlaD 0.78 17
Dickeya dianthicola ME23 0.61 DZA65_RS09455 DUF3413 domain-containing protein 0.72 DZA65_RS01555 outer membrane lipid asymmetry maintenance protein MlaD low > 75
Pectobacterium carotovorum WPP14 0.61 HER17_RS12985 LPS biosynthesis-modulating metalloenzyme YejM 0.73 HER17_RS20015 outer membrane lipid asymmetry maintenance protein MlaD low > 75
Vibrio cholerae E7946 ATCC 55056 0.38 CSW01_10200 DUF3413 domain-containing protein 0.39 CSW01_12765 outer membrane lipid asymmetry maintenance protein MlaD low > 62
Shewanella sp. ANA-3 0.24 Shewana3_2428 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase (RefSeq) 0.38 Shewana3_0680 hypothetical protein (RefSeq) low > 73
Shewanella oneidensis MR-1 0.24 SO2175 conserved hypothetical protein (NCBI ptt file) 0.38 SO3952 mce-related protein (NCBI ptt file) 0.59 9
Shewanella loihica PV-4 0.22 Shew_1470 sulfatase (RefSeq) 0.38 Shew_3302 hypothetical protein (RefSeq) low > 60
Shewanella amazonensis SB2B 0.19 Sama_1555 hypothetical protein (RefSeq) 0.40 Sama_3079 mce-related protein (RefSeq) low > 62

Not shown: 1 genomes with orthologs for BWI76_RS19845 only; 41 genomes with orthologs for BWI76_RS25220 only