Conservation of cofitness between BWI76_RS05165 and BWI76_RS18955 in Klebsiella michiganensis M5al

30 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Klebsiella michiganensis M5al 1.0 BWI76_RS05165 cobalamin-binding protein 1.0 BWI76_RS18955 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase 0.34 12
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.76 GFF63 Vitamin B12 ABC transporter, B12-binding component BtuF 0.80 GFF3906 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) / Phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) low > 78
Escherichia coli ECRC62 0.74 BNILDI_09055 btuF vitamin B12 ABC transporter substrate-binding protein BtuF 0.88 BNILDI_14710 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE low > 75
Escherichia coli ECRC99 0.74 KEDOAH_17885 btuF vitamin B12 ABC transporter substrate-binding protein BtuF 0.82 KEDOAH_03665 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE — —
Escherichia coli ECRC98 0.74 JDDGAC_13865 btuF vitamin B12 ABC transporter substrate-binding protein BtuF 0.82 JDDGAC_28595 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE low > 86
Escherichia fergusonii Becca 0.74 EFB2_03886 Vitamin B12-binding protein 0.82 EFB2_01830 Histidine biosynthesis bifunctional protein HisIE 0.33 52
Escherichia coli ECRC102 0.74 NIAGMN_08120 btuF vitamin B12 ABC transporter substrate-binding protein BtuF 0.82 NIAGMN_22430 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE — —
Escherichia coli ECRC100 0.74 OKFHMN_10270 btuF vitamin B12 ABC transporter substrate-binding protein BtuF 0.82 OKFHMN_24485 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE low > 80
Escherichia coli ECOR27 0.74 NOLOHH_02615 btuF vitamin B12 ABC transporter substrate-binding protein BtuF 0.83 NOLOHH_15800 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE low > 75
Escherichia coli ECRC101 0.74 MCAODC_00785 btuF vitamin B12 ABC transporter substrate-binding protein BtuF 0.82 MCAODC_20455 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE low > 87
Escherichia coli HS(pFamp)R (ATCC 700891) 0.74 OHPLBJKB_03504 Vitamin B12-binding protein 0.87 OHPLBJKB_01674 Histidine biosynthesis bifunctional protein HisIE low > 73
Escherichia coli BW25113 0.74 b0158 btuF vitamin B12-transporter protein BtuF (NCBI) 0.89 b2026 hisI bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein (NCBI) low > 76
Escherichia coli ECOR38 0.74 HEPCGN_08220 btuF vitamin B12 ABC transporter substrate-binding protein BtuF 0.88 HEPCGN_03190 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE 0.58 62
Escherichia coli BL21 0.74 ECD_00157 vitamin B12 ABC transporter periplasmic binding protein 0.89 ECD_01928 phosphoribosyl-AMP cyclohydrolase and phosphoribosyl-ATP pyrophosphatase low > 61
Enterobacter sp. TBS_079 0.74 MPMX20_00844 Vitamin B12-binding protein 0.87 MPMX20_03008 Histidine biosynthesis bifunctional protein HisIE 0.31 23
Escherichia coli Nissle 1917 0.74 ECOLIN_RS00880 vitamin B12 ABC transporter substrate-binding protein BtuF 0.82 ECOLIN_RS11975 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE — —
Enterobacter asburiae PDN3 0.70 EX28DRAFT_3747 ABC-type Fe3+-hydroxamate transport system, periplasmic component 0.88 EX28DRAFT_0533 phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19)/phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) low > 76
Serratia liquefaciens MT49 0.56 IAI46_03570 vitamin B12 ABC transporter substrate-binding protein BtuF 0.73 IAI46_08180 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE low > 86
Rahnella sp. WP5 0.52 EX31_RS03185 vitamin B12 ABC transporter substrate-binding protein BtuF 0.77 EX31_RS11470 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE low > 89
Dickeya dadantii 3937 0.51 DDA3937_RS15875 vitamin B12 ABC transporter substrate-binding protein BtuF 0.82 DDA3937_RS09705 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE low > 74
Pantoea sp. MT58 0.50 IAI47_15575 vitamin B12 ABC transporter substrate-binding protein BtuF 0.76 IAI47_07060 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE low > 76
Dickeya dianthicola ME23 0.50 DZA65_RS17100 vitamin B12 ABC transporter substrate-binding protein BtuF 0.80 DZA65_RS10025 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE low > 75
Dickeya dianthicola 67-19 0.50 HGI48_RS16015 vitamin B12 ABC transporter substrate-binding protein BtuF 0.80 HGI48_RS09715 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE low > 71
Pectobacterium carotovorum WPP14 0.50 HER17_RS05645 vitamin B12 ABC transporter substrate-binding protein BtuF 0.72 HER17_RS12260 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE low > 75
Vibrio cholerae E7946 ATCC 55056 0.37 CSW01_12055 cobalamin-binding protein 0.64 CSW01_05780 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase low > 62
Shewanella sp. ANA-3 0.28 Shewana3_3272 periplasmic binding protein (RefSeq) 0.60 Shewana3_1847 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein (RefSeq) low > 73
Shewanella oneidensis MR-1 0.28 SO3709 ABC transporter, periplasmic substrate-binding protein, putative (NCBI ptt file) 0.62 SO2067 hisI phosphoribosyl-ATP pyrophosphatase/phosphoribosyl-AMP cyclohydrolase (NCBI ptt file) 0.61 51
Shewanella amazonensis SB2B 0.27 Sama_2869 ABC transporter, periplasmic substrate-binding protein, putative (RefSeq) 0.60 Sama_1948 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein (RefSeq) 0.83 42
Shewanella loihica PV-4 0.26 Shew_0719 periplasmic binding protein (RefSeq) 0.58 Shew_2204 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein (RefSeq) 0.74 9
Pontibacter actiniarum KMM 6156, DSM 19842 0.13 CA264_01385 iron ABC transporter substrate-binding protein 0.48 CA264_05115 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase low > 74
Mucilaginibacter yixingensis YX-36 DSM 26809 0.11 ABZR88_RS12705 helical backbone metal receptor 0.55 ABZR88_RS06845 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE — —

Not shown: 28 genomes with orthologs for BWI76_RS05165 only; 19 genomes with orthologs for BWI76_RS18955 only