Conservation of cofitness between BWI76_RS04250 and BWI76_RS11850 in Klebsiella michiganensis M5al

30 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Klebsiella michiganensis M5al 1.0 BWI76_RS04250 homoserine kinase 1.0 BWI76_RS11850 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase 0.92 13
Enterobacter asburiae PDN3 0.93 EX28DRAFT_3615 homoserine kinase (EC 2.7.1.39) 0.85 EX28DRAFT_0934 indole-3-glycerol phosphate synthase (EC 4.1.1.48) — —
Enterobacter sp. TBS_079 0.92 MPMX20_00711 Homoserine kinase 0.84 MPMX20_02512 Tryptophan biosynthesis protein TrpCF 0.92 25
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.90 GFF1079 Homoserine kinase (EC 2.7.1.39) 0.83 GFF2724 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) / Phosphoribosylanthranilate isomerase (EC 5.3.1.24) low > 78
Escherichia coli BW25113 0.89 b0003 thrB homoserine kinase (NCBI) 0.83 b1262 trpC N-(5-phosphoribosyl)anthranilate isomerase and indole-3-glycerolphosphate synthetase (VIMSS) 0.87 44
Escherichia coli ECOR27 0.89 NOLOHH_03435 thrB homoserine kinase 0.84 NOLOHH_20325 trpD bifunctional anthranilate synthase glutamate amidotransferase component TrpG/anthranilate phosphoribosyltransferase TrpD 0.88 40
Escherichia coli ECRC62 0.89 BNILDI_08165 thrB homoserine kinase 0.84 BNILDI_18470 trpD bifunctional anthranilate synthase glutamate amidotransferase component TrpG/anthranilate phosphoribosyltransferase TrpD 0.90 61
Escherichia coli ECOR38 0.89 HEPCGN_09110 thrB homoserine kinase 0.84 HEPCGN_25525 trpCF bifunctional indole-3-glycerol-phosphate synthase TrpC/phosphoribosylanthranilate isomerase TrpF 0.78 61
Escherichia coli BL21 0.89 ECD_00003 homoserine kinase 0.84 ECD_01236 indole-3-glycerolphosphate synthetase and N-(5-phosphoribosyl)anthranilate isomerase low > 61
Escherichia coli HS(pFamp)R (ATCC 700891) 0.89 OHPLBJKB_03657 Homoserine kinase 0.84 OHPLBJKB_02421 Tryptophan biosynthesis protein TrpCF low > 73
Escherichia coli ECRC100 0.89 OKFHMN_11105 thrB homoserine kinase 0.83 OKFHMN_02665 trpCF bifunctional indole-3-glycerol-phosphate synthase TrpC/phosphoribosylanthranilate isomerase TrpF low > 80
Escherichia coli ECRC101 0.89 MCAODC_01620 thrB homoserine kinase 0.83 MCAODC_15600 trpCF bifunctional indole-3-glycerol-phosphate synthase TrpC/phosphoribosylanthranilate isomerase TrpF 0.73 66
Escherichia coli ECRC98 0.89 JDDGAC_14700 thrB homoserine kinase 0.83 JDDGAC_05210 trpCF bifunctional indole-3-glycerol-phosphate synthase TrpC/phosphoribosylanthranilate isomerase TrpF 0.90 32
Escherichia coli ECRC99 0.89 KEDOAH_17050 thrB homoserine kinase 0.83 KEDOAH_26085 trpCF bifunctional indole-3-glycerol-phosphate synthase TrpC/phosphoribosylanthranilate isomerase TrpF — —
Escherichia coli ECRC102 0.89 NIAGMN_08955 thrB homoserine kinase 0.83 NIAGMN_26835 trpCF bifunctional indole-3-glycerol-phosphate synthase TrpC/phosphoribosylanthranilate isomerase TrpF — —
Escherichia coli Nissle 1917 0.89 ECOLIN_RS00015 homoserine kinase 0.84 ECOLIN_RS07605 bifunctional indole-3-glycerol-phosphate synthase TrpC/phosphoribosylanthranilate isomerase TrpF low > 55
Escherichia fergusonii Becca 0.89 EFB2_04040 Homoserine kinase 0.84 EFB2_02664 Tryptophan biosynthesis protein TrpCF low > 86
Rahnella sp. WP5 0.85 EX31_RS03940 homoserine kinase 0.76 EX31_RS09970 bifunctional indole-3-glycerol-phosphate synthase TrpC/phosphoribosylanthranilate isomerase TrpF 0.97 24
Serratia liquefaciens MT49 0.84 IAI46_03035 homoserine kinase 0.76 IAI46_14035 bifunctional indole-3-glycerol-phosphate synthase TrpC/phosphoribosylanthranilate isomerase TrpF low > 86
Pantoea sp. MT58 0.84 IAI47_16210 homoserine kinase 0.77 IAI47_09175 bifunctional indole-3-glycerol-phosphate synthase TrpC/phosphoribosylanthranilate isomerase TrpF 0.90 32
Pectobacterium carotovorum WPP14 0.83 HER17_RS02800 homoserine kinase 0.69 HER17_RS10930 bifunctional indole-3-glycerol-phosphate synthase TrpC/phosphoribosylanthranilate isomerase TrpF 0.84 46
Dickeya dadantii 3937 0.82 DDA3937_RS18410 homoserine kinase 0.70 DDA3937_RS10470 bifunctional indole-3-glycerol-phosphate synthase TrpC/phosphoribosylanthranilate isomerase TrpF 0.75 44
Dickeya dianthicola 67-19 0.81 HGI48_RS18340 homoserine kinase 0.67 HGI48_RS10470 bifunctional indole-3-glycerol-phosphate synthase TrpC/phosphoribosylanthranilate isomerase TrpF low > 71
Dickeya dianthicola ME23 0.81 DZA65_RS19480 homoserine kinase 0.67 DZA65_RS10950 bifunctional indole-3-glycerol-phosphate synthase TrpC/phosphoribosylanthranilate isomerase TrpF 0.63 72
Erwinia tracheiphila SCR3 0.79 LU632_RS02615 thrB homoserine kinase 0.71 LU632_RS12765 trpCF bifunctional indole-3-glycerol-phosphate synthase TrpC/phosphoribosylanthranilate isomerase TrpF low > 74
Vibrio cholerae E7946 ATCC 55056 0.74 CSW01_11970 homoserine kinase 0.60 CSW01_05935 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase 0.58 50
Shewanella amazonensis SB2B 0.53 Sama_0906 homoserine kinase (RefSeq) 0.47 Sama_2132 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase (RefSeq) 0.89 51
Shewanella loihica PV-4 0.53 Shew_1080 homoserine kinase (RefSeq) 0.45 Shew_2254 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase (RefSeq) 0.86 49
Shewanella sp. ANA-3 0.52 Shewana3_1140 homoserine kinase (RefSeq) 0.41 Shewana3_1517 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase (RefSeq) 0.93 16
Shewanella oneidensis MR-1 0.51 SO3414 thrB homoserine kinase (NCBI ptt file) 0.39 SO3022 trpC/F indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase (NCBI ptt file) 0.91 40
Alteromonas macleodii MIT1002 0.50 MIT1002_03085 Homoserine kinase 0.48 MIT1002_01427 Tryptophan biosynthesis protein TrpCF 0.92 35

Not shown: 12 genomes with orthologs for BWI76_RS04250 only; 1 genomes with orthologs for BWI76_RS11850 only