Conservation of cofitness between BWI76_RS04245 and BWI76_RS11850 in Klebsiella michiganensis M5al

30 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Klebsiella michiganensis M5al 1.0 BWI76_RS04245 bifunctional aspartate kinase/homoserine dehydrogenase I 1.0 BWI76_RS11850 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase 0.93 13
Escherichia coli BW25113 0.92 b0002 thrA bifunctional aspartokinase I/homeserine dehydrogenase I (NCBI) 0.83 b1262 trpC N-(5-phosphoribosyl)anthranilate isomerase and indole-3-glycerolphosphate synthetase (VIMSS) 0.90 39
Escherichia coli ECOR38 0.92 HEPCGN_09115 thrA bifunctional aspartate kinase/homoserine dehydrogenase I 0.84 HEPCGN_25525 trpCF bifunctional indole-3-glycerol-phosphate synthase TrpC/phosphoribosylanthranilate isomerase TrpF 0.89 60
Escherichia coli ECRC98 0.92 JDDGAC_14705 thrA bifunctional aspartate kinase/homoserine dehydrogenase I 0.83 JDDGAC_05210 trpCF bifunctional indole-3-glycerol-phosphate synthase TrpC/phosphoribosylanthranilate isomerase TrpF 0.93 18
Escherichia coli ECRC99 0.92 KEDOAH_17045 thrA bifunctional aspartate kinase/homoserine dehydrogenase I 0.83 KEDOAH_26085 trpCF bifunctional indole-3-glycerol-phosphate synthase TrpC/phosphoribosylanthranilate isomerase TrpF — —
Escherichia fergusonii Becca 0.92 EFB2_04041 Bifunctional aspartokinase/homoserine dehydrogenase 1 0.84 EFB2_02664 Tryptophan biosynthesis protein TrpCF 0.30 42
Escherichia coli ECRC100 0.92 OKFHMN_11110 thrA bifunctional aspartate kinase/homoserine dehydrogenase I 0.83 OKFHMN_02665 trpCF bifunctional indole-3-glycerol-phosphate synthase TrpC/phosphoribosylanthranilate isomerase TrpF low > 80
Escherichia coli ECRC101 0.92 MCAODC_01625 thrA bifunctional aspartate kinase/homoserine dehydrogenase I 0.83 MCAODC_15600 trpCF bifunctional indole-3-glycerol-phosphate synthase TrpC/phosphoribosylanthranilate isomerase TrpF 0.69 73
Escherichia coli ECRC102 0.92 NIAGMN_08960 thrA bifunctional aspartate kinase/homoserine dehydrogenase I 0.83 NIAGMN_26835 trpCF bifunctional indole-3-glycerol-phosphate synthase TrpC/phosphoribosylanthranilate isomerase TrpF — —
Escherichia coli BL21 0.92 ECD_00002 Bifunctional aspartokinase/homoserine dehydrogenase 1 0.84 ECD_01236 indole-3-glycerolphosphate synthetase and N-(5-phosphoribosyl)anthranilate isomerase 0.71 57
Escherichia coli HS(pFamp)R (ATCC 700891) 0.92 OHPLBJKB_03658 Bifunctional aspartokinase/homoserine dehydrogenase 1 0.84 OHPLBJKB_02421 Tryptophan biosynthesis protein TrpCF low > 73
Escherichia coli ECOR27 0.92 NOLOHH_03440 thrA bifunctional aspartate kinase/homoserine dehydrogenase I 0.84 NOLOHH_20325 trpD bifunctional anthranilate synthase glutamate amidotransferase component TrpG/anthranilate phosphoribosyltransferase TrpD 0.89 43
Escherichia coli ECRC62 0.92 BNILDI_08160 thrA bifunctional aspartate kinase/homoserine dehydrogenase I 0.84 BNILDI_18470 trpD bifunctional anthranilate synthase glutamate amidotransferase component TrpG/anthranilate phosphoribosyltransferase TrpD 0.90 65
Escherichia coli Nissle 1917 0.92 ECOLIN_RS00010 bifunctional aspartate kinase/homoserine dehydrogenase I 0.84 ECOLIN_RS07605 bifunctional indole-3-glycerol-phosphate synthase TrpC/phosphoribosylanthranilate isomerase TrpF 0.44 40
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.92 GFF1078 Aspartokinase (EC 2.7.2.4) / Homoserine dehydrogenase (EC 1.1.1.3) 0.83 GFF2724 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) / Phosphoribosylanthranilate isomerase (EC 5.3.1.24) 0.50 11
Enterobacter sp. TBS_079 0.90 MPMX20_00710 Bifunctional aspartokinase/homoserine dehydrogenase 1 0.84 MPMX20_02512 Tryptophan biosynthesis protein TrpCF 0.93 18
Enterobacter asburiae PDN3 0.89 EX28DRAFT_3614 aspartate kinase (EC 2.7.2.4) 0.85 EX28DRAFT_0934 indole-3-glycerol phosphate synthase (EC 4.1.1.48) 0.62 68
Rahnella sp. WP5 0.85 EX31_RS03945 bifunctional aspartate kinase/homoserine dehydrogenase I 0.76 EX31_RS09970 bifunctional indole-3-glycerol-phosphate synthase TrpC/phosphoribosylanthranilate isomerase TrpF 0.97 21
Pantoea sp. MT58 0.84 IAI47_16215 bifunctional aspartate kinase/homoserine dehydrogenase I 0.77 IAI47_09175 bifunctional indole-3-glycerol-phosphate synthase TrpC/phosphoribosylanthranilate isomerase TrpF 0.93 28
Serratia liquefaciens MT49 0.84 IAI46_03030 bifunctional aspartate kinase/homoserine dehydrogenase I 0.76 IAI46_14035 bifunctional indole-3-glycerol-phosphate synthase TrpC/phosphoribosylanthranilate isomerase TrpF low > 86
Pectobacterium carotovorum WPP14 0.83 HER17_RS02795 bifunctional aspartate kinase/homoserine dehydrogenase I 0.69 HER17_RS10930 bifunctional indole-3-glycerol-phosphate synthase TrpC/phosphoribosylanthranilate isomerase TrpF 0.91 40
Erwinia tracheiphila SCR3 0.83 LU632_RS02610 thrA bifunctional aspartate kinase/homoserine dehydrogenase I 0.71 LU632_RS12765 trpCF bifunctional indole-3-glycerol-phosphate synthase TrpC/phosphoribosylanthranilate isomerase TrpF low > 74
Dickeya dadantii 3937 0.80 DDA3937_RS18415 bifunctional aspartate kinase/homoserine dehydrogenase I 0.70 DDA3937_RS10470 bifunctional indole-3-glycerol-phosphate synthase TrpC/phosphoribosylanthranilate isomerase TrpF 0.73 74
Dickeya dianthicola ME23 0.80 DZA65_RS19485 bifunctional aspartate kinase/homoserine dehydrogenase I 0.67 DZA65_RS10950 bifunctional indole-3-glycerol-phosphate synthase TrpC/phosphoribosylanthranilate isomerase TrpF low > 75
Dickeya dianthicola 67-19 0.80 HGI48_RS18345 bifunctional aspartate kinase/homoserine dehydrogenase I 0.67 HGI48_RS10470 bifunctional indole-3-glycerol-phosphate synthase TrpC/phosphoribosylanthranilate isomerase TrpF low > 71
Vibrio cholerae E7946 ATCC 55056 0.62 CSW01_11975 bifunctional aspartate kinase/homoserine dehydrogenase I 0.60 CSW01_05935 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase low > 62
Shewanella loihica PV-4 0.57 Shew_1079 thrA bifunctional aspartokinase I/homeserine dehydrogenase I (RefSeq) 0.45 Shew_2254 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase (RefSeq) 0.90 47
Shewanella oneidensis MR-1 0.56 SO3415 thrA aspartokinase I/homoserine dehydrogenase, threonine-sensitive (NCBI ptt file) 0.39 SO3022 trpC/F indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase (NCBI ptt file) 0.83 34
Shewanella sp. ANA-3 0.56 Shewana3_1139 thrA bifunctional aspartokinase I/homeserine dehydrogenase I (RefSeq) 0.41 Shewana3_1517 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase (RefSeq) 0.92 24
Alteromonas macleodii MIT1002 0.53 MIT1002_03086 Aspartokinase I/homoserine dehydrogenase I 0.48 MIT1002_01427 Tryptophan biosynthesis protein TrpCF 0.93 50
Shewanella amazonensis SB2B 0.53 Sama_0905 thrA bifunctional aspartokinase I/homeserine dehydrogenase I (RefSeq) 0.47 Sama_2132 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase (RefSeq) 0.87 52

Not shown: 11 genomes with orthologs for BWI76_RS04245 only; 1 genomes with orthologs for BWI76_RS11850 only