Conservation of cofitness between BWI76_RS00805 and BWI76_RS11850 in Klebsiella michiganensis M5al

31 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Klebsiella michiganensis M5al 1.0 BWI76_RS00805 5,10-methylenetetrahydrofolate reductase 1.0 BWI76_RS11850 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase 0.90 14
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.96 GFF2329 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) 0.83 GFF2724 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) / Phosphoribosylanthranilate isomerase (EC 5.3.1.24) low > 78
Enterobacter asburiae PDN3 0.95 EX28DRAFT_4413 5,10-methylenetetrahydrofolate reductase, prokaryotic form 0.85 EX28DRAFT_0934 indole-3-glycerol phosphate synthase (EC 4.1.1.48) low > 76
Escherichia coli HS(pFamp)R (ATCC 700891) 0.95 OHPLBJKB_04109 5,10-methylenetetrahydrofolate reductase 0.84 OHPLBJKB_02421 Tryptophan biosynthesis protein TrpCF low > 73
Enterobacter sp. TBS_079 0.95 MPMX20_04529 5,10-methylenetetrahydrofolate reductase 0.84 MPMX20_02512 Tryptophan biosynthesis protein TrpCF 0.71 33
Escherichia coli BL21 0.95 ECD_03827 5,10-methylenetetrahydrofolate reductase 0.84 ECD_01236 indole-3-glycerolphosphate synthetase and N-(5-phosphoribosyl)anthranilate isomerase low > 61
Escherichia coli ECOR27 0.95 NOLOHH_05810 metF methylenetetrahydrofolate reductase 0.84 NOLOHH_20325 trpD bifunctional anthranilate synthase glutamate amidotransferase component TrpG/anthranilate phosphoribosyltransferase TrpD 0.93 41
Escherichia coli ECRC62 0.95 BNILDI_05725 metF methylenetetrahydrofolate reductase 0.84 BNILDI_18470 trpD bifunctional anthranilate synthase glutamate amidotransferase component TrpG/anthranilate phosphoribosyltransferase TrpD 0.89 72
Escherichia coli BW25113 0.95 b3941 metF 5,10-methylenetetrahydrofolate reductase (NCBI) 0.83 b1262 trpC N-(5-phosphoribosyl)anthranilate isomerase and indole-3-glycerolphosphate synthetase (VIMSS) 0.92 43
Escherichia coli ECRC99 0.95 KEDOAH_14495 metF methylenetetrahydrofolate reductase 0.83 KEDOAH_26085 trpCF bifunctional indole-3-glycerol-phosphate synthase TrpC/phosphoribosylanthranilate isomerase TrpF
Escherichia coli ECRC102 0.95 NIAGMN_11420 metF methylenetetrahydrofolate reductase 0.83 NIAGMN_26835 trpCF bifunctional indole-3-glycerol-phosphate synthase TrpC/phosphoribosylanthranilate isomerase TrpF
Escherichia coli ECRC101 0.95 MCAODC_04165 metF methylenetetrahydrofolate reductase 0.83 MCAODC_15600 trpCF bifunctional indole-3-glycerol-phosphate synthase TrpC/phosphoribosylanthranilate isomerase TrpF 0.89 39
Escherichia coli ECRC100 0.95 OKFHMN_13665 metF methylenetetrahydrofolate reductase 0.83 OKFHMN_02665 trpCF bifunctional indole-3-glycerol-phosphate synthase TrpC/phosphoribosylanthranilate isomerase TrpF low > 80
Escherichia coli ECRC98 0.95 JDDGAC_17290 metF methylenetetrahydrofolate reductase 0.83 JDDGAC_05210 trpCF bifunctional indole-3-glycerol-phosphate synthase TrpC/phosphoribosylanthranilate isomerase TrpF 0.95 20
Escherichia coli ECOR38 0.95 HEPCGN_12310 metF methylenetetrahydrofolate reductase 0.84 HEPCGN_25525 trpCF bifunctional indole-3-glycerol-phosphate synthase TrpC/phosphoribosylanthranilate isomerase TrpF 0.81 72
Escherichia fergusonii Becca 0.94 EFB2_04672 5,10-methylenetetrahydrofolate reductase 0.84 EFB2_02664 Tryptophan biosynthesis protein TrpCF low > 86
Escherichia coli Nissle 1917 0.94 ECOLIN_RS22760 methylenetetrahydrofolate reductase 0.84 ECOLIN_RS07605 bifunctional indole-3-glycerol-phosphate synthase TrpC/phosphoribosylanthranilate isomerase TrpF low > 55
Pantoea sp. MT58 0.92 IAI47_00890 methylenetetrahydrofolate reductase 0.77 IAI47_09175 bifunctional indole-3-glycerol-phosphate synthase TrpC/phosphoribosylanthranilate isomerase TrpF 0.46 57
Serratia liquefaciens MT49 0.92 IAI46_24530 methylenetetrahydrofolate reductase 0.76 IAI46_14035 bifunctional indole-3-glycerol-phosphate synthase TrpC/phosphoribosylanthranilate isomerase TrpF low > 86
Dickeya dadantii 3937 0.91 DDA3937_RS00960 methylenetetrahydrofolate reductase 0.70 DDA3937_RS10470 bifunctional indole-3-glycerol-phosphate synthase TrpC/phosphoribosylanthranilate isomerase TrpF low > 74
Rahnella sp. WP5 0.91 EX31_RS14205 methylenetetrahydrofolate reductase 0.76 EX31_RS09970 bifunctional indole-3-glycerol-phosphate synthase TrpC/phosphoribosylanthranilate isomerase TrpF 0.91 19
Pectobacterium carotovorum WPP14 0.90 HER17_RS00950 methylenetetrahydrofolate reductase 0.69 HER17_RS10930 bifunctional indole-3-glycerol-phosphate synthase TrpC/phosphoribosylanthranilate isomerase TrpF low > 75
Dickeya dianthicola 67-19 0.90 HGI48_RS20415 methylenetetrahydrofolate reductase 0.67 HGI48_RS10470 bifunctional indole-3-glycerol-phosphate synthase TrpC/phosphoribosylanthranilate isomerase TrpF low > 71
Dickeya dianthicola ME23 0.90 DZA65_RS21460 methylenetetrahydrofolate reductase 0.67 DZA65_RS10950 bifunctional indole-3-glycerol-phosphate synthase TrpC/phosphoribosylanthranilate isomerase TrpF low > 75
Erwinia tracheiphila SCR3 0.87 LU632_RS19630 metF methylenetetrahydrofolate reductase 0.71 LU632_RS12765 trpCF bifunctional indole-3-glycerol-phosphate synthase TrpC/phosphoribosylanthranilate isomerase TrpF low > 74
Vibrio cholerae E7946 ATCC 55056 0.78 CSW01_13560 methylenetetrahydrofolate reductase 0.60 CSW01_05935 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase low > 62
Shewanella oneidensis MR-1 0.76 SO4054 metF 5,10-methylenetetrahydrofolate reductase (NCBI ptt file) 0.39 SO3022 trpC/F indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase (NCBI ptt file) 0.90 49
Shewanella amazonensis SB2B 0.76 Sama_3169 metF 5,10-methylenetetrahydrofolate reductase (RefSeq) 0.47 Sama_2132 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase (RefSeq) 0.92 48
Shewanella sp. ANA-3 0.76 Shewana3_3612 metF 5,10-methylenetetrahydrofolate reductase (RefSeq) 0.41 Shewana3_1517 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase (RefSeq) 0.95 22
Shewanella loihica PV-4 0.75 Shew_0522 metF 5,10-methylenetetrahydrofolate reductase (RefSeq) 0.45 Shew_2254 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase (RefSeq) 0.91 46
Alteromonas macleodii MIT1002 0.70 MIT1002_03670 5,10-methylenetetrahydrofolate reductase 0.48 MIT1002_01427 Tryptophan biosynthesis protein TrpCF low > 70
Kangiella aquimarina DSM 16071 0.61 B158DRAFT_2461 5,10-methylenetetrahydrofolate reductase (NAD(P)) (EC 1.5.1.20) 0.36 B158DRAFT_2428 indole-3-glycerol phosphate synthase (EC 4.1.1.48) low > 40

Not shown: 68 genomes with orthologs for BWI76_RS00805 only; 0 genomes with orthologs for BWI76_RS11850 only