Conservation of cofitness between b0074 and b3774 in Escherichia coli BW25113

29 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BW25113 1.0 b0074 leuA 2-isopropylmalate synthase (NCBI) 1.0 b3774 ilvC ketol-acid reductoisomerase (NCBI) 0.98 5
Escherichia coli BL21 1.00 ECD_00076 2-isopropylmalate synthase 1.00 ECD_03652 ketol-acid reductoisomerase, NAD(P)-binding 0.73 7
Escherichia coli ECOR27 1.00 NOLOHH_03060 2-isopropylmalate synthase 1.00 NOLOHH_06760 ilvC ketol-acid reductoisomerase low > 57
Escherichia coli ECRC62 1.00 BNILDI_08550 2-isopropylmalate synthase 1.00 BNILDI_04765 ilvC ketol-acid reductoisomerase — —
Escherichia fergusonii Becca 1.00 EFB2_03971 2-isopropylmalate synthase 1.00 EFB2_04862 Ketol-acid reductoisomerase (NADP(+)) low > 86
Escherichia coli Nissle 1917 1.00 ECOLIN_RS00400 2-isopropylmalate synthase 1.00 ECOLIN_RS21680 ketol-acid reductoisomerase low > 52
Escherichia coli ECOR38 1.00 HEPCGN_08695 2-isopropylmalate synthase 1.00 HEPCGN_13335 ilvC ketol-acid reductoisomerase low > 85
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_03583 2-isopropylmalate synthase 1.00 OHPLBJKB_04279 Ketol-acid reductoisomerase (NADP(+)) low > 73
Escherichia coli ECRC102 1.00 NIAGMN_08565 2-isopropylmalate synthase 1.00 NIAGMN_12380 ilvC ketol-acid reductoisomerase — —
Escherichia coli ECRC99 1.00 KEDOAH_17440 2-isopropylmalate synthase 1.00 KEDOAH_13525 ilvC ketol-acid reductoisomerase — —
Escherichia coli ECRC101 1.00 MCAODC_01230 2-isopropylmalate synthase 1.00 MCAODC_05130 ilvC ketol-acid reductoisomerase — —
Escherichia coli ECRC101 1.00 OKFHMN_10715 2-isopropylmalate synthase 1.00 OKFHMN_14625 ilvC ketol-acid reductoisomerase — —
Escherichia coli ECRC98 1.00 JDDGAC_14310 2-isopropylmalate synthase 1.00 JDDGAC_18245 ilvC ketol-acid reductoisomerase — —
Klebsiella michiganensis M5al 0.95 BWI76_RS04680 2-isopropylmalate synthase 0.96 BWI76_RS00990 ketol-acid reductoisomerase 0.94 6
Enterobacter asburiae PDN3 0.94 EX28DRAFT_3670 2-isopropylmalate synthase (EC 2.3.3.13) 0.95 EX28DRAFT_4446 ketol-acid reductoisomerase (EC 1.1.1.86) 0.87 13
Enterobacter sp. TBS_079 0.94 MPMX20_00769 2-isopropylmalate synthase 0.95 MPMX20_04496 Ketol-acid reductoisomerase (NADP(+)) 0.91 23
Pectobacterium carotovorum WPP14 0.87 HER17_RS03085 2-isopropylmalate synthase 0.89 HER17_RS01100 ketol-acid reductoisomerase 0.99 4
Erwinia tracheiphila SCR3 0.86 LU632_RS02880 leuA 2-isopropylmalate synthase 0.90 LU632_RS24385 ilvC ketol-acid reductoisomerase 0.86 10
Dickeya dianthicola 67-19 0.86 HGI48_RS18055 2-isopropylmalate synthase 0.89 HGI48_RS20270 ketol-acid reductoisomerase 0.83 24
Dickeya dadantii 3937 0.86 DDA3937_RS18115 2-isopropylmalate synthase 0.89 DDA3937_RS20130 ketol-acid reductoisomerase 0.71 52
Dickeya dianthicola ME23 0.86 DZA65_RS19200 2-isopropylmalate synthase 0.89 DZA65_RS21310 ketol-acid reductoisomerase 0.92 7
Serratia liquefaciens MT49 0.85 IAI46_03355 2-isopropylmalate synthase 0.90 IAI46_24325 ketol-acid reductoisomerase 0.74 8
Pantoea sp. MT58 0.84 IAI47_16000 2-isopropylmalate synthase 0.90 IAI47_01050 ketol-acid reductoisomerase 0.98 11
Rahnella sp. WP5 0.82 EX31_RS03680 2-isopropylmalate synthase 0.90 EX31_RS15020 ketol-acid reductoisomerase 0.96 16
Vibrio cholerae E7946 ATCC 55056 0.69 CSW01_12595 2-isopropylmalate synthase 0.76 CSW01_00840 ketol-acid reductoisomerase low > 62
Shewanella amazonensis SB2B 0.67 Sama_0335 2-isopropylmalate synthase (RefSeq) 0.75 Sama_3282 ketol-acid reductoisomerase (RefSeq) 0.96 10
Shewanella sp. ANA-3 0.66 Shewana3_3761 2-isopropylmalate synthase (RefSeq) 0.74 Shewana3_0355 ketol-acid reductoisomerase (RefSeq) 0.96 5
Shewanella oneidensis MR-1 0.66 SO4236 leuA 2-isopropylmalate synthase (NCBI ptt file) 0.74 SO4349 ilvC ketol-acid reductoisomerase (NCBI ptt file) 0.99 3
Shewanella loihica PV-4 0.66 Shew_3472 2-isopropylmalate synthase (RefSeq) 0.73 Shew_0288 ketol-acid reductoisomerase (RefSeq) 0.98 21
Alteromonas macleodii MIT1002 0.62 MIT1002_00949 2-isopropylmalate synthase 0.73 MIT1002_04045 Ketol-acid reductoisomerase 0.96 28

Not shown: 59 genomes with orthologs for b0074 only; 2 genomes with orthologs for b3774 only