Conservation of cofitness between b1850 and b0904 in Escherichia coli BW25113

31 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BW25113 1.0 b1850 eda keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase (NCBI) 1.0 b0904 focA formate transporter (NCBI) 0.38 8
Escherichia coli ECRC98 1.00 JDDGAC_00920 kdgA bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 1.00 JDDGAC_09115 focA formate transporter FocA — —
Escherichia coli ECRC99 1.00 KEDOAH_01760 kdgA bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 1.00 KEDOAH_22230 focA formate transporter FocA — —
Escherichia coli BL21 1.00 ECD_01821 KHG/KDPG aldolase; 2-dehydro-3-deoxy-phosphogluconate/4-hydroxy-2- oxoglutarate aldolase 1.00 ECD_00908 formate channel — —
Escherichia coli ECRC101 1.00 MCAODC_19060 kdgA bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 1.00 MCAODC_24895 focA formate transporter FocA — —
Escherichia coli Nissle 1917 1.00 ECOLIN_RS10305 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 1.00 ECOLIN_RS04790 formate transporter FocA — —
Escherichia coli ECRC102 1.00 NIAGMN_01715 kdgA bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 1.00 NIAGMN_03225 focA formate transporter FocA — —
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_01879 KHG/KDPG aldolase 1.00 OHPLBJKB_02764 putative formate transporter 1 low > 73
Escherichia coli ECRC101 1.00 OKFHMN_26345 kdgA bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 1.00 OKFHMN_05505 focA formate transporter FocA — —
Escherichia coli ECRC62 1.00 BNILDI_15650 kdgA bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 1.00 BNILDI_20320 focA formate transporter FocA — —
Escherichia coli ECOR27 0.99 NOLOHH_16855 kdgA bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 1.00 NOLOHH_22065 focA formate transporter FocA — —
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.97 GFF1629 4-hydroxy-2-oxoglutarate aldolase (EC 4.1.3.16) @ 2-dehydro-3-deoxyphosphogluconate aldolase (EC 4.1.2.14) 0.92 GFF3661 Formate efflux transporter (TC 2.A.44 family) low > 78
Enterobacter sp. TBS_079 0.96 MPMX20_02755 KHG/KDPG aldolase 0.89 MPMX20_01563 putative formate transporter 1 low > 85
Pectobacterium carotovorum WPP14 0.91 HER17_RS11775 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.80 HER17_RS12300 formate transporter FocA low > 75
Dickeya dadantii 3937 0.91 DDA3937_RS10140 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.82 DDA3937_RS09660 formate transporter FocA low > 74
Dickeya dianthicola ME23 0.91 DZA65_RS10585 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.81 DZA65_RS09980 formate transporter FocA low > 75
Dickeya dianthicola 67-19 0.91 HGI48_RS10170 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.80 HGI48_RS09670 formate transporter FocA low > 71
Pantoea sp. MT58 0.89 IAI47_08500 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.79 IAI47_12875 formate transporter FocA low > 76
Rahnella sp. WP5 0.88 EX31_RS10625 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.85 EX31_RS18265 formate transporter FocA low > 89
Serratia liquefaciens MT49 0.88 IAI46_14570 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.87 IAI46_08615 formate transporter FocA low > 86
Klebsiella michiganensis M5al 0.87 BWI76_RS18095 ketohydroxyglutarate aldolase 0.96 BWI76_RS09740 formate transporter FocA — —
Erwinia tracheiphila SCR3 0.81 LU632_RS13355 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.80 LU632_RS09780 focA formate transporter FocA low > 74
Alteromonas macleodii MIT1002 0.66 MIT1002_02403 KHG/KDPG aldolase 0.15 MIT1002_01529 Formate channel 1 — —
Marinobacter adhaerens HP15 0.49 HP15_2177 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase 0.12 HP15_3885 formate and nitrite transporter low > 73
Pseudomonas stutzeri RCH2 0.49 Psest_0854 Entner-Doudoroff aldolase 0.13 Psest_2408 Formate/nitrite family of transporters — —
Variovorax sp. OAS795 0.48 ABID97_RS21295 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.14 ABID97_RS16035 formate/nitrite transporter family protein — —
Pseudomonas sp. S08-1 0.48 OH686_02425 4-hydroxy-2-oxoglutarate aldolase or 2-dehydro-3-deoxyphosphogluconate aldolase 0.15 OH686_20565 Nitrite transporter from formate/nitrite family low > 80
Pseudomonas syringae pv. syringae B728a 0.46 Psyr_1122 2-keto-3-deoxy-phosphogluconate aldolase 0.23 Psyr_4660 Formate/nitrite transporter — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.46 Psyr_1122 2-keto-3-deoxy-phosphogluconate aldolase 0.23 Psyr_4660 Formate/nitrite transporter — —
Bosea sp. OAE506 0.45 ABIE41_RS23505 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.25 ABIE41_RS15280 formate/nitrite transporter family protein low > 77
Vibrio cholerae E7946 ATCC 55056 0.40 CSW01_01465 ketohydroxyglutarate aldolase 0.55 CSW01_08525 formate transporter FocA low > 62
Azospirillum brasilense Sp245 0.39 AZOBR_RS29850 ketohydroxyglutarate aldolase 0.36 AZOBR_RS30145 formate transporter — —

Not shown: 53 genomes with orthologs for b1850 only; 6 genomes with orthologs for b0904 only