Conservation of cofitness between Rv3291c and Rv1872c in Mycobacterium tuberculosis H37Rv

16 genomes with putative orthologs of both genes

Organism	Ratio1	Gene1	Name1	Description1	Ratio2	Gene2	Name2	Description2	Cofit	Rank
Mycobacterium tuberculosis H37Rv	1.0	Rv3291c		Probable transcriptional regulatory protein LrpA (Lrp/AsnC-family)	1.0	Rv1872c		Possible L-lactate dehydrogenase (cytochrome) LldD2	low	> 58
Hydrogenophaga sp. GW460-11-11-14-LB1	0.35	GFF135		Transcriptional regulator, AsnC family	0.54	GFF5624		L-lactate dehydrogenase (EC 1.1.2.3)	—	—
Acidovorax sp. GW101-3H11	0.33	Ac3H11_4553		Transcriptional regulator, AsnC family	0.34	Ac3H11_1623		L-lactate dehydrogenase (cytochrome) (EC 1.1.2.3) (from data)	low	> 79
Azospirillum brasilense Sp245	0.32	AZOBR_RS09655		AsnC family transcriptional regulator	0.27	AZOBR_RS27055		L-lactate dehydrogenase	low	> 97
Pseudomonas sp. S08-1	0.30	OH686_03725		Transcriptional regulator, AsnC family	0.27	OH686_17010		L-lactate dehydrogenase	low	> 80
Pseudomonas putida KT2440	0.28	PP_4308		Transcriptional regulator, AsnC family	0.28	PP_4736		L-lactate dehydrogenase	low	> 96
Vibrio cholerae E7946 ATCC 55056	0.28	CSW01_09530		leucine-responsive transcriptional regulator Lrp	0.29	CSW01_19035		alpha-hydroxy-acid oxidizing enzyme	—	—
Burkholderia phytofirmans PsJN	0.27	BPHYT_RS14785		AsnC family transcriptional regulator	0.24	BPHYT_RS31690		hypothetical protein	low	> 109
Pseudomonas fluorescens SBW25-INTG	0.27	PFLU_RS15180		Lrp/AsnC family transcriptional regulator	0.34	PFLU_RS17610		alpha-hydroxy-acid oxidizing protein	low	> 109
Pseudomonas fluorescens SBW25	0.27	PFLU_RS15180		Lrp/AsnC family transcriptional regulator	0.34	PFLU_RS17610		alpha-hydroxy-acid oxidizing protein	low	> 109
Pseudomonas simiae WCS417	0.27	PS417_13660		AsnC family transcriptional regulator	0.34	PS417_15625		lactate dehydrogenase	low	> 88
Paraburkholderia graminis OAS925	0.26	ABIE53_003132		Lrp/AsnC family leucine-responsive transcriptional regulator	0.32	ABIE53_005317		(S)-mandelate dehydrogenase	low	> 113
Variovorax sp. OAS795	0.26	ABID97_RS22380		winged helix-turn-helix transcriptional regulator	0.34	ABID97_RS08010		alpha-hydroxy acid oxidase	low	> 91
Variovorax sp. SCN45	0.25	GFF1774		Leucine-responsive regulatory protein, regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system	0.34	GFF5984		L-lactate dehydrogenase	low	> 127
Sinorhizobium meliloti 1021	0.25	SMc00425		transcriptional regulator	0.32	SM_b20850		L-lactate dehydrogenase (cytochrome) (EC 1.1.2.3) (from data)	low	> 103
Ralstonia solanacearum PSI07	0.25	RPSI07_RS19595		AsnC family transcriptional regulator	0.34	RPSI07_RS14000		alpha-hydroxy-acid oxidizing protein	low	> 81
Pedobacter sp. GW460-11-11-14-LB5	0.23	CA265_RS10770		AsnC family transcriptional regulator	0.25	CA265_RS08335		alpha-hydroxy-acid oxidizing enzyme	low	> 88

Not shown: 14 genomes with orthologs for Rv3291c only; 41 genomes with orthologs for Rv1872c only