Conservation of cofitness between CSW01_11730 and CSW01_10020 in Vibrio cholerae E7946 ATCC 55056

35 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_11730 2-dehydropantoate 2-reductase 1.0 CSW01_10020 ROK family protein 0.83 6
Rahnella sp. WP5 0.38 EX31_RS22180 2-dehydropantoate 2-reductase 0.50 EX31_RS16985 ROK family transcriptional regulator low > 89
Enterobacter sp. TBS_079 0.36 MPMX20_01016 2-dehydropantoate 2-reductase 0.47 MPMX20_02063 Protein mlc low > 85
Serratia liquefaciens MT49 0.35 IAI46_04950 2-dehydropantoate 2-reductase 0.50 IAI46_11685 ROK family transcriptional regulator low > 87
Escherichia coli ECRC98 0.35 JDDGAC_12050 panE 2-dehydropantoate 2-reductase 0.47 JDDGAC_02330 mlc DNA-binding transcriptional repressor Mlc low > 87
Escherichia coli ECRC99 0.35 KEDOAH_19570 panE 2-dehydropantoate 2-reductase 0.47 KEDOAH_00365 mlc DNA-binding transcriptional repressor Mlc — —
Escherichia coli BW25113 0.35 b0425 panE 2-dehydropantoate 2-reductase (NCBI) 0.46 b1594 dgsA DNA-binding transcriptional repressor (NCBI) low > 76
Escherichia coli ECRC102 0.35 NIAGMN_06450 panE 2-dehydropantoate 2-reductase 0.47 NIAGMN_00335 mlc DNA-binding transcriptional repressor Mlc low > 80
Escherichia coli ECRC100 0.35 OKFHMN_08395 panE 2-dehydropantoate 2-reductase 0.47 OKFHMN_27740 mlc DNA-binding transcriptional repressor Mlc low > 79
Escherichia coli ECRC101 0.35 MCAODC_27620 panE 2-dehydropantoate 2-reductase 0.47 MCAODC_17670 mlc DNA-binding transcriptional repressor Mlc low > 87
Enterobacter asburiae PDN3 0.35 EX28DRAFT_2546 2-dehydropantoate 2-reductase 0.48 EX28DRAFT_1493 Transcriptional regulator/sugar kinase low > 76
Escherichia coli BL21 0.35 ECD_00373 2-dehydropantoate reductase, NADPH-specific 0.46 ECD_01563 glucosamine anaerobic growth regulon transcriptional repressor; autorepressor — —
Escherichia coli HS(pFamp)R (ATCC 700891) 0.35 OHPLBJKB_03251 2-dehydropantoate 2-reductase 0.46 OHPLBJKB_02132 Protein mlc low > 74
Escherichia coli ECOR38 0.35 HEPCGN_07025 panE 2-dehydropantoate 2-reductase 0.47 HEPCGN_06115 mlc DNA-binding transcriptional repressor Mlc low > 88
Escherichia coli ECOR27 0.35 NOLOHH_01345 panE 2-dehydropantoate 2-reductase 0.47 NOLOHH_18245 mlc DNA-binding transcriptional repressor Mlc low > 76
Escherichia coli ECRC62 0.35 BNILDI_22760 panE 2-dehydropantoate 2-reductase 0.47 BNILDI_17035 mlc DNA-binding transcriptional repressor Mlc low > 75
Escherichia fergusonii Becca 0.35 EFB2_03632 2-dehydropantoate 2-reductase 0.47 EFB2_02398 Protein mlc low > 86
Klebsiella pneumoniae MKP103 0.35 KDGMDA_14500 2-dehydropantoate 2-reductase 0.48 KDGMDA_21230 transcriptional regulator low > 95
Escherichia coli Nissle 1917 0.34 ECOLIN_RS02560 2-dehydropantoate 2-reductase 0.47 ECOLIN_RS08905 sugar metabolism global transcriptional regulator Mlc — —
Pectobacterium carotovorum WPP14 0.34 HER17_RS15910 2-dehydropantoate 2-reductase 0.50 HER17_RS10735 ROK family transcriptional regulator low > 75
Klebsiella michiganensis M5al 0.34 BWI76_RS06405 2-dehydropantoate 2-reductase 0.47 BWI76_RS15955 transcriptional regulator low > 92
Dickeya dianthicola ME23 0.34 DZA65_RS05940 2-dehydropantoate 2-reductase 0.49 DZA65_RS11145 ROK family transcriptional regulator low > 75
Dickeya dianthicola 67-19 0.33 HGI48_RS05615 2-dehydropantoate 2-reductase 0.49 HGI48_RS10675 ROK family transcriptional regulator low > 71
Pantoea agglomerans CFBP13505 P0401 0.32 PagCFBP13505_RS10480 2-dehydropantoate 2-reductase 0.45 PagCFBP13505_RS06405 ROK family transcriptional regulator low > 74
Pantoea sp. MT58 0.32 IAI47_14715 2-dehydropantoate 2-reductase 0.45 IAI47_09750 ROK family transcriptional regulator low > 76
Dickeya dadantii 3937 0.32 DDA3937_RS05555 2-dehydropantoate 2-reductase 0.50 DDA3937_RS10675 ROK family transcriptional regulator low > 74
Erwinia tracheiphila SCR3 0.32 LU632_RS18455 panE 2-dehydropantoate 2-reductase 0.47 LU632_RS12305 ROK family transcriptional regulator low > 73
Erwinia tracheiphila HP pepo 2.2 0.32 IJEDHG_16335 panE 2-dehydropantoate 2-reductase 0.47 IJEDHG_23280 transcriptional regulator low > 61
Erwinia amylovora T8 0.32 OLJFJH_18040 2-dehydropantoate 2-reductase 0.48 OLJFJH_14275 transcriptional regulator low > 58
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.30 GFF4336 2-dehydropantoate 2-reductase (EC 1.1.1.169) 0.47 GFF1785 Mlc, transcriptional repressor of MalT (the transcriptional activator of maltose regulon) and manXYZ operon low > 78
Bosea sp. OAE506 0.20 ABIE41_RS11280 2-dehydropantoate 2-reductase 0.18 ABIE41_RS06840 ROK family protein low > 77
Variovorax sp. OAS795 0.18 ABID97_RS00870 2-dehydropantoate 2-reductase 0.17 ABID97_RS00440 ROK family protein low > 91
Pontibacter actiniarum KMM 6156, DSM 19842 0.11 CA264_06150 hypothetical protein 0.20 CA264_08710 sugar kinase low > 74
Caulobacter crescentus NA1000 0.10 CCNA_00262 ketopantoate reductase panE/ApbA family protein 0.09 CCNA_01870 NagC-family transcriptional regulator low > 66
Caulobacter crescentus NA1000 Δfur 0.10 CCNA_00262 ketopantoate reductase panE/ApbA family protein 0.09 CCNA_01870 NagC-family transcriptional regulator low > 67
Azospirillum brasilense Sp245 0.09 AZOBR_RS12955 2-dehydropantoate 2-reductase 0.17 AZOBR_RS27950 transcriptional regulator — —

Not shown: 50 genomes with orthologs for CSW01_11730 only; 10 genomes with orthologs for CSW01_10020 only