Conservation of cofitness between BWI76_RS19375 and BWI76_RS01530 in Klebsiella michiganensis M5al

35 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Klebsiella michiganensis M5al 1.0 BWI76_RS19375 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 1.0 BWI76_RS01530 2-iminoacetate synthase ThiH 0.31 5
Escherichia coli ECRC100 0.93 OKFHMN_24075 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.91 OKFHMN_13400 thiH 2-iminoacetate synthase ThiH 0.78 57
Escherichia coli ECRC98 0.93 JDDGAC_28185 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.91 JDDGAC_17025 thiH 2-iminoacetate synthase ThiH low > 86
Escherichia coli ECRC99 0.93 KEDOAH_04075 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.91 KEDOAH_14760 thiH 2-iminoacetate synthase ThiH — —
Escherichia coli ECRC101 0.93 MCAODC_21085 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.91 MCAODC_03900 thiH 2-iminoacetate synthase ThiH 0.82 7
Escherichia coli ECRC102 0.93 NIAGMN_22020 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.91 NIAGMN_11150 thiH 2-iminoacetate synthase ThiH — —
Escherichia coli HS(pFamp)R (ATCC 700891) 0.93 OHPLBJKB_01607 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.91 OHPLBJKB_04061 2-iminoacetate synthase low > 73
Escherichia coli BW25113 0.93 b2103 thiD phosphomethylpyrimidine kinase (NCBI) 0.91 b3990 thiH thiamine biosynthesis protein ThiH (NCBI) 0.86 5
Escherichia coli ECOR27 0.93 NOLOHH_15415 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.91 NOLOHH_05545 thiH 2-iminoacetate synthase ThiH 0.87 5
Escherichia coli ECRC62 0.93 BNILDI_14330 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.91 BNILDI_05980 thiH 2-iminoacetate synthase ThiH low > 75
Escherichia coli BL21 0.92 ECD_02031 hydroxy-methylpyrimidine kinase and hydroxy-phosphomethylpyrimidine kinase 0.90 ECD_03866 tyrosine lyase, involved in thiamine-thiazole moiety synthesis low > 61
Escherichia fergusonii Becca 0.92 EFB2_01754 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.90 EFB2_04622 2-iminoacetate synthase low > 86
Escherichia coli ECOR38 0.92 HEPCGN_02760 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.91 HEPCGN_12035 thiH 2-iminoacetate synthase ThiH 0.87 7
Escherichia coli Nissle 1917 0.91 ECOLIN_RS12335 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.90 ECOLIN_RS23015 2-iminoacetate synthase ThiH — —
Enterobacter sp. TBS_079 0.90 MPMX20_03076 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.91 MPMX20_00212 2-iminoacetate synthase 0.33 61
Enterobacter asburiae PDN3 0.90 EX28DRAFT_0469 hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.90 EX28DRAFT_4531 thiazole biosynthesis protein ThiH 0.62 8
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.90 GFF3834 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) 0.91 GFF4203 Thiazole biosynthesis protein ThiH low > 78
Pectobacterium carotovorum WPP14 0.79 HER17_RS06265 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.80 HER17_RS20405 2-iminoacetate synthase ThiH 0.90 5
Serratia liquefaciens MT49 0.77 IAI46_19100 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.80 IAI46_01295 2-iminoacetate synthase ThiH low > 86
Rahnella sp. WP5 0.77 EX31_RS20390 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.77 EX31_RS16790 2-iminoacetate synthase ThiH low > 89
Dickeya dianthicola 67-19 0.76 HGI48_RS15410 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.81 HGI48_RS01145 2-iminoacetate synthase ThiH 0.88 1
Dickeya dadantii 3937 0.76 DDA3937_RS15335 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.81 DDA3937_RS01150 2-iminoacetate synthase ThiH 0.85 3
Dickeya dianthicola ME23 0.76 DZA65_RS16235 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.81 DZA65_RS01190 2-iminoacetate synthase ThiH 0.94 1
Erwinia tracheiphila SCR3 0.75 LU632_RS08590 thiD bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.77 LU632_RS00945 thiH 2-iminoacetate synthase ThiH low > 74
Vibrio cholerae E7946 ATCC 55056 0.40 CSW01_06545 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.63 CSW01_00360 2-iminoacetate synthase ThiH low > 62
Phocaeicola vulgatus CL09T03C04 0.39 HMPREF1058_RS06820 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.45 HMPREF1058_RS03265 2-iminoacetate synthase ThiH 0.98 1
Phocaeicola dorei CL03T12C01 0.39 ABI39_RS20615 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.45 ABI39_RS17775 2-iminoacetate synthase ThiH 0.97 1
Bacteroides stercoris CC31F 0.38 HMPREF1181_RS14705 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.46 HMPREF1181_RS14690 2-iminoacetate synthase ThiH 0.66 25
Bacteroides thetaiotaomicron VPI-5482 0.36 BT0790 phosphomethylpyrimidine kinase (NCBI ptt file) 0.45 BT0649 thiamine biosynthesis protein ThiH (NCBI ptt file) 0.44 10
Echinicola vietnamensis KMM 6221, DSM 17526 0.36 Echvi_0215 phosphomethylpyrimidine kinase 0.52 Echvi_3563 thiazole biosynthesis protein ThiH 0.32 6
Bacteroides ovatus ATCC 8483 0.35 BACOVA_02530 phosphomethylpyrimidine kinase 0.46 BACOVA_02357 thiazole biosynthesis protein ThiH 0.92 3
Pedobacter sp. GW460-11-11-14-LB5 0.34 CA265_RS24160 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.53 CA265_RS20185 2-iminoacetate synthase ThiH low > 88
Mucilaginibacter yixingensis YX-36 DSM 26809 0.31 ABZR88_RS08810 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.56 ABZR88_RS08820 2-iminoacetate synthase ThiH 0.88 4
Fusobacterium nucleatum SB010 0.30 HUW76_10300 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.32 HUW76_10270 2-iminoacetate synthase ThiH low > 35
Desulfovibrio vulgaris Miyazaki F 0.28 DvMF_1376 phosphomethylpyrimidine kinase (RefSeq) 0.38 DvMF_0799 thiH thiamine biosynthesis protein ThiH (RefSeq) — —
Pontibacter actiniarum KMM 6156, DSM 19842 0.20 CA264_20430 hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.52 CA264_20415 2-iminoacetate synthase ThiH low > 74

Not shown: 53 genomes with orthologs for BWI76_RS19375 only; 5 genomes with orthologs for BWI76_RS01530 only