Conservation of cofitness between BWI76_RS18345 and BWI76_RS01165 in Klebsiella michiganensis M5al

30 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Klebsiella michiganensis M5al 1.0 BWI76_RS18345 transcriptional regulator SdiA 1.0 BWI76_RS01165 protoheme IX biogenesis protein HemY 0.37 9
Enterobacter asburiae PDN3 0.73 EX28DRAFT_0631 DNA-binding HTH domain-containing proteins 0.86 EX28DRAFT_4471 heme biosynthesis-associated TPR protein low > 76
Enterobacter sp. TBS_079 0.72 MPMX20_02841 Regulatory protein SdiA 0.85 MPMX20_04473 Protein HemY low > 85
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.68 GFF1696 N-3-oxohexanoyl-L-homoserine lactone quorum-sensing transcriptional activator @ N-3-oxooctanoyl-L-homoserine lactone quorum-sensing transcriptional activator 0.85 GFF226 Uncharacterized protein EC-HemY, likely associated with heme metabolism based on gene clustering with hemC, hemD in Proteobacteria (unrelated to HemY-type PPO in GramPositives) low > 78
Escherichia coli HS(pFamp)R (ATCC 700891) 0.68 OHPLBJKB_01813 Regulatory protein SdiA 0.90 OHPLBJKB_04251 Protein HemY low > 73
Escherichia coli ECOR27 0.67 NOLOHH_16430 sdiA transcriptional regulator SdiA 0.90 NOLOHH_06610 hemY protoheme IX biogenesis protein HemY low > 75
Escherichia coli ECRC62 0.67 BNILDI_15220 sdiA transcriptional regulator SdiA 0.90 BNILDI_04925 hemY protoheme IX biogenesis protein HemY low > 75
Escherichia coli ECRC99 0.67 KEDOAH_02280 sdiA transcriptional regulator SdiA 0.90 KEDOAH_13685 hemY protoheme IX biogenesis protein HemY
Escherichia coli ECRC100 0.67 OKFHMN_25810 sdiA transcriptional regulator SdiA 0.90 OKFHMN_14465 hemY protoheme IX biogenesis protein HemY low > 80
Escherichia coli ECRC102 0.67 NIAGMN_02240 sdiA transcriptional regulator SdiA 0.90 NIAGMN_12220 hemY protoheme IX biogenesis protein HemY
Escherichia coli ECRC101 0.67 MCAODC_19580 sdiA transcriptional regulator SdiA 0.90 MCAODC_04970 hemY protoheme IX biogenesis protein HemY low > 87
Escherichia coli ECRC98 0.67 JDDGAC_00400 sdiA transcriptional regulator SdiA 0.90 JDDGAC_18090 hemY protoheme IX biogenesis protein HemY low > 86
Escherichia coli BW25113 0.67 b1916 sdiA DNA-binding transcriptional activator (NCBI) 0.90 b3802 hemY predicted protoheme IX synthesis protein (NCBI) low > 76
Escherichia coli ECOR38 0.67 HEPCGN_04165 sdiA transcriptional regulator SdiA 0.90 HEPCGN_13185 hemY protoheme IX biogenesis protein HemY low > 87
Escherichia coli Nissle 1917 0.67 ECOLIN_RS10915 transcriptional regulator SdiA 0.90 ECOLIN_RS21820 protoheme IX biogenesis protein HemY low > 55
Escherichia fergusonii Becca 0.67 EFB2_02030 Regulatory protein SdiA 0.90 EFB2_04836 Protein HemY low > 86
Pantoea sp. MT58 0.49 IAI47_12485 transcriptional regulator SdiA 0.70 IAI47_18440 protoheme IX biogenesis protein HemY low > 76
Ralstonia sp. UNC404CL21Col 0.27 ABZR87_RS22810 autoinducer binding domain-containing protein 0.07 ABZR87_RS16125 heme biosynthesis protein HemY low > 80
Pseudomonas putida KT2440 0.26 PP_4647 transcriptional regulator, LuxR family 0.12 PP_0189 putative heme biosynthesis protein low > 96
Pseudomonas sp. RS175 0.19 PFR28_02249 hypothetical protein 0.12 PFR28_04363 Protein HemY low > 88
Pseudomonas fluorescens GW456-L13 0.19 PfGW456L13_1439 Transcriptional activator protein SolR 0.12 PfGW456L13_859 Uncharacterized protein EC-HemY, likely associated with heme metabolism based on gene clustering with hemC, hemD in Proteobacteria (unrelated to HemY-type PPO in GramPositives) low > 87
Pseudomonas simiae WCS417 0.19 PS417_24330 LuxR family transcriptional regulator 0.12 PS417_27515 heme biosynthesis protein HemY low > 88
Pseudomonas fluorescens FW300-N2C3 0.19 AO356_15655 zinc protease 0.14 AO356_12800 heme biosynthesis protein HemY low > 104
Serratia liquefaciens MT49 0.19 IAI46_09125 LuxR family transcriptional regulator 0.68 IAI46_00680 protoheme IX biogenesis protein HemY low > 86
Pseudomonas fluorescens SBW25 0.17 PFLU_RS26255 LuxR family transcriptional regulator 0.12 PFLU_RS29195 heme biosynthesis protein HemY low > 109
Pseudomonas fluorescens SBW25-INTG 0.17 PFLU_RS26255 LuxR family transcriptional regulator 0.12 PFLU_RS29195 heme biosynthesis protein HemY low > 109
Pseudomonas fluorescens FW300-N2E3 0.17 AO353_13955 hypothetical protein 0.12 AO353_08975 heme biosynthesis protein HemY low > 101
Pseudomonas syringae pv. syringae B728a ΔmexB 0.16 Psyr_1622 regulatory protein, LuxR:Autoinducer-binding protein 0.11 Psyr_0059 HemY, N-terminal:HemY, N-terminal:HemY, N-terminal low > 86
Pseudomonas syringae pv. syringae B728a 0.16 Psyr_1622 regulatory protein, LuxR:Autoinducer-binding protein 0.11 Psyr_0059 HemY, N-terminal:HemY, N-terminal:HemY, N-terminal low > 86
Pectobacterium carotovorum WPP14 0.16 HER17_RS13915 LuxR family transcriptional regulator 0.69 HER17_RS01300 protoheme IX biogenesis protein HemY low > 75
Dickeya dadantii 3937 0.13 DDA3937_RS20730 LuxR family transcriptional regulator 0.66 DDA3937_RS19935 protoheme IX biogenesis protein HemY low > 74

Not shown: 6 genomes with orthologs for BWI76_RS18345 only; 15 genomes with orthologs for BWI76_RS01165 only