Conservation of cofitness between BT1222 and BT1747 in Bacteroides thetaiotaomicron VPI-5482

30 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Bacteroides thetaiotaomicron VPI-5482 1.0 BT1222 6-phosphogluconate dehydrogenase,decarboxylating (NCBI ptt file) 1.0 BT1747 pyruvate-flavodoxin oxidoreductase (NCBI ptt file) 0.52 4
Bacteroides ovatus ATCC 8483 0.94 BACOVA_00509 phosphogluconate dehydrogenase (decarboxylating) 0.98 BACOVA_04490 pyruvate synthase low > 94
Bacteroides stercoris CC31F 0.87 HMPREF1181_RS12525 decarboxylating NADP(+)-dependent phosphogluconate dehydrogenase 0.95 HMPREF1181_RS05665 pyruvate:ferredoxin (flavodoxin) oxidoreductase low > 56
Phocaeicola dorei CL03T12C01 0.62 ABI39_RS14350 decarboxylating NADP(+)-dependent phosphogluconate dehydrogenase 0.91 ABI39_RS18745 pyruvate:ferredoxin (flavodoxin) oxidoreductase low > 72
Phocaeicola vulgatus CL09T03C04 0.61 HMPREF1058_RS18025 decarboxylating NADP(+)-dependent phosphogluconate dehydrogenase 0.91 HMPREF1058_RS05140 pyruvate:ferredoxin (flavodoxin) oxidoreductase 0.35 52
Parabacteroides merdae CL09T00C40 0.57 HMPREF1078_RS08640 decarboxylating NADP(+)-dependent phosphogluconate dehydrogenase 0.87 HMPREF1078_RS07845 pyruvate:ferredoxin (flavodoxin) oxidoreductase low > 61
Vibrio cholerae E7946 ATCC 55056 0.52 CSW01_18635 phosphogluconate dehydrogenase (NADP(+)-dependent, decarboxylating) 0.32 CSW01_16885 pyruvate:ferredoxin (flavodoxin) oxidoreductase low > 62
Escherichia coli HS(pFamp)R (ATCC 700891) 0.47 OHPLBJKB_01659 6-phosphogluconate dehydrogenase, decarboxylating 0.44 OHPLBJKB_02334 Pyruvate-flavodoxin oxidoreductase low > 73
Enterobacter sp. TBS_079 0.47 MPMX20_03014 6-phosphogluconate dehydrogenase, decarboxylating 0.44 MPMX20_02432 Pyruvate-flavodoxin oxidoreductase low > 85
Escherichia coli ECRC101 0.47 OKFHMN_24470 gndA NADP-dependent phosphogluconate dehydrogenase 0.45 OKFHMN_01810 nifJ pyruvate:ferredoxin (flavodoxin) oxidoreductase — —
Escherichia coli ECRC102 0.47 NIAGMN_22415 gndA NADP-dependent phosphogluconate dehydrogenase 0.45 NIAGMN_25945 nifJ pyruvate:ferredoxin (flavodoxin) oxidoreductase — —
Escherichia coli ECRC99 0.47 KEDOAH_03680 gndA NADP-dependent phosphogluconate dehydrogenase 0.45 KEDOAH_26625 nifJ pyruvate:ferredoxin (flavodoxin) oxidoreductase — —
Escherichia coli ECRC101 0.47 MCAODC_20470 gndA NADP-dependent phosphogluconate dehydrogenase 0.45 MCAODC_16125 nifJ pyruvate:ferredoxin (flavodoxin) oxidoreductase — —
Klebsiella michiganensis M5al 0.47 BWI76_RS19025 phosphogluconate dehydrogenase (NADP(+)-dependent, decarboxylating) 0.56 BWI76_RS18805 pyruvate:ferredoxin (flavodoxin) oxidoreductase low > 92
Escherichia coli BW25113 0.47 b2029 gnd 6-phosphogluconate dehydrogenase (NCBI) 0.44 b1378 ydbK fused predicted pyruvate-flavodoxin oxidoreductase: conserved protein/conserved protein/FeS binding protein (NCBI) low > 76
Escherichia coli ECRC98 0.47 JDDGAC_28580 gndA NADP-dependent phosphogluconate dehydrogenase 0.45 JDDGAC_04300 nifJ pyruvate:ferredoxin (flavodoxin) oxidoreductase — —
Escherichia fergusonii Becca 0.47 EFB2_01826 6-phosphogluconate dehydrogenase, decarboxylating 0.44 EFB2_02579 Pyruvate-flavodoxin oxidoreductase 0.31 62
Escherichia coli ECOR27 0.47 NOLOHH_15785 gndA NADP-dependent phosphogluconate dehydrogenase 0.44 NOLOHH_19545 nifJ pyruvate:ferredoxin (flavodoxin) oxidoreductase — —
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.47 GFF3903 6-phosphogluconate dehydrogenase, decarboxylating (EC 1.1.1.44) 0.44 GFF2642 Pyruvate-flavodoxin oxidoreductase (EC 1.2.7.-) low > 78
Escherichia coli ECRC62 0.47 BNILDI_14695 gndA NADP-dependent phosphogluconate dehydrogenase 0.44 BNILDI_18000 nifJ pyruvate:ferredoxin (flavodoxin) oxidoreductase — —
Escherichia coli Nissle 1917 0.47 ECOLIN_RS11990 NADP-dependent phosphogluconate dehydrogenase 0.44 ECOLIN_RS08095 pyruvate:ferredoxin (flavodoxin) oxidoreductase low > 52
Enterobacter asburiae PDN3 0.47 EX28DRAFT_0529 6-phosphogluconate dehydrogenase (decarboxylating) 0.44 EX28DRAFT_1018 pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric low > 76
Escherichia coli BL21 0.47 ECD_01931 6-phosphogluconate dehydrogenase, decarboxylating 0.44 ECD_01349 pyruvate-flavodoxin oxidoreductase low > 60
Synechococcus elongatus PCC 7942 0.46 Synpcc7942_0039 gnd 6-phosphogluconate dehydrogenase 0.43 Synpcc7942_2384 nifJ Pyruvate:ferredoxin (flavodoxin) oxidoreductase low > 38
Escherichia coli ECOR38 0.46 HEPCGN_03175 gndA NADP-dependent phosphogluconate dehydrogenase 0.44 HEPCGN_26025 nifJ pyruvate:ferredoxin (flavodoxin) oxidoreductase low > 85
Rahnella sp. WP5 0.46 EX31_RS11475 NADP-dependent phosphogluconate dehydrogenase 0.56 EX31_RS15420 pyruvate:ferredoxin (flavodoxin) oxidoreductase — —
Pectobacterium carotovorum WPP14 0.46 HER17_RS14505 NADP-dependent phosphogluconate dehydrogenase 0.43 HER17_RS17565 pyruvate:ferredoxin (flavodoxin) oxidoreductase low > 75
Serratia liquefaciens MT49 0.46 IAI46_08160 NADP-dependent phosphogluconate dehydrogenase 0.44 IAI46_13375 pyruvate:ferredoxin (flavodoxin) oxidoreductase — —
Dickeya dianthicola ME23 0.46 DZA65_RS07180 NADP-dependent phosphogluconate dehydrogenase 0.56 DZA65_RS20040 pyruvate:ferredoxin (flavodoxin) oxidoreductase low > 75
Dickeya dadantii 3937 0.45 DDA3937_RS06805 NADP-dependent phosphogluconate dehydrogenase 0.57 DDA3937_RS18930 pyruvate:ferredoxin (flavodoxin) oxidoreductase low > 74
Dickeya dianthicola 67-19 0.45 HGI48_RS06840 NADP-dependent phosphogluconate dehydrogenase 0.56 HGI48_RS18935 pyruvate:ferredoxin (flavodoxin) oxidoreductase low > 71

Not shown: 23 genomes with orthologs for BT1222 only; 7 genomes with orthologs for BT1747 only