Conservation of cofitness between b2264 and b3424 in Escherichia coli BW25113

28 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BW25113 1.0 b2264 menD 2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase (NCBI) 1.0 b3424 glpG predicted intramembrane serine protease (NCBI) 0.25 17
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_01446 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase 1.00 OHPLBJKB_00280 Rhomboid protease GlpG low > 73
Escherichia coli BL21 1.00 ECD_02191 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase; SEPHCHC synthase 1.00 ECD_03275 rhomboid intramembrane serine protease low > 60
Escherichia coli ECRC62 0.99 BNILDI_13475 menD 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene- 1-carboxylic-acid synthase 1.00 BNILDI_02785 glpG rhomboid family intramembrane serine protease GlpG — —
Escherichia coli ECOR27 0.99 NOLOHH_14560 menD 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene- 1-carboxylic-acid synthase 1.00 NOLOHH_08730 glpG rhomboid family intramembrane serine protease GlpG low > 57
Escherichia coli ECOR38 0.99 HEPCGN_22150 menD 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene- 1-carboxylic-acid synthase 0.99 HEPCGN_15755 glpG rhomboid family intramembrane serine protease GlpG low > 85
Escherichia coli ECRC99 0.99 KEDOAH_05260 menD 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene- 1-carboxylic-acid synthase 1.00 KEDOAH_11205 glpG rhomboid family intramembrane serine protease GlpG — —
Escherichia coli ECRC98 0.99 JDDGAC_26900 menD 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene- 1-carboxylic-acid synthase 1.00 JDDGAC_20565 glpG rhomboid family intramembrane serine protease GlpG — —
Escherichia coli ECRC102 0.99 NIAGMN_20705 menD 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene- 1-carboxylic-acid synthase 1.00 NIAGMN_14705 glpG rhomboid family intramembrane serine protease GlpG — —
Escherichia coli ECRC101 0.99 MCAODC_13975 menD 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene- 1-carboxylic-acid synthase 1.00 MCAODC_07465 glpG rhomboid family intramembrane serine protease GlpG — —
Escherichia coli ECRC101 0.99 OKFHMN_22935 menD 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene- 1-carboxylic-acid synthase 1.00 OKFHMN_16935 glpG rhomboid family intramembrane serine protease GlpG — —
Escherichia fergusonii Becca 0.99 EFB2_01591 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase 0.98 EFB2_00405 Rhomboid protease GlpG low > 86
Escherichia coli Nissle 1917 0.99 ECOLIN_RS13185 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase 1.00 ECOLIN_RS26040 rhomboid family intramembrane serine protease GlpG — —
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.92 GFF1870 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase (EC 2.2.1.9) 0.91 GFF589 GlpG protein (membrane protein of glp regulon) low > 78
Enterobacter sp. TBS_079 0.85 MPMX20_03200 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase 0.87 MPMX20_04307 Rhomboid protease GlpG low > 85
Klebsiella michiganensis M5al 0.85 BWI76_RS20075 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase 0.86 BWI76_RS26180 rhomboid family intramembrane serine protease GlpG low > 92
Enterobacter asburiae PDN3 0.84 EX28DRAFT_0340 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase 0.87 EX28DRAFT_4122 rhomboid family protease GlpG low > 76
Serratia liquefaciens MT49 0.71 IAI46_17560 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase 0.58 IAI46_23905 rhomboid family intramembrane serine protease GlpG low > 86
Pectobacterium carotovorum WPP14 0.68 HER17_RS15555 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase 0.57 HER17_RS01525 rhomboid family intramembrane serine protease GlpG low > 75
Dickeya dadantii 3937 0.66 DDA3937_RS05915 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase 0.52 DDA3937_RS19675 rhomboid family intramembrane serine protease GlpG low > 74
Dickeya dianthicola 67-19 0.66 HGI48_RS05960 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase 0.52 HGI48_RS19805 rhomboid family intramembrane serine protease GlpG low > 71
Dickeya dianthicola ME23 0.65 DZA65_RS06295 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase 0.51 DZA65_RS20895 rhomboid family intramembrane serine protease GlpG low > 75
Rahnella sp. WP5 0.64 EX31_RS19355 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase 0.48 EX31_RS04990 rhomboid family intramembrane serine protease GlpG low > 89
Erwinia tracheiphila SCR3 0.61 LU632_RS08105 menD 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase 0.61 LU632_RS23010 glpG rhomboid family intramembrane serine protease GlpG low > 74
Vibrio cholerae E7946 ATCC 55056 0.37 CSW01_09860 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase 0.38 CSW01_00530 rhomboid family intramembrane serine protease GlpG low > 62
Shewanella amazonensis SB2B 0.35 Sama_3460 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase (RefSeq) 0.36 Sama_0095 glpG protein (RefSeq) low > 62
Shewanella sp. ANA-3 0.35 Shewana3_3965 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase (RefSeq) 0.39 Shewana3_4107 rhomboid family protein (RefSeq) low > 73
Shewanella oneidensis MR-1 0.34 SO4573 menD 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid synthase/2-oxoglutarate decarboxylase (NCBI ptt file) 0.38 SO4671 glpG glpG protein (NCBI ptt file) low > 76
Shewanella loihica PV-4 0.33 Shew_3599 2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylic acid synthase/2-oxoglutarate decarboxylase (RefSeq) 0.39 Shew_3712 rhomboid family protein (RefSeq) low > 60

Not shown: 11 genomes with orthologs for b2264 only; 13 genomes with orthologs for b3424 only