Conservation of cofitness between Pf6N2E2_4154 and Pf6N2E2_149 in Pseudomonas fluorescens FW300-N2E2

28 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Pseudomonas fluorescens FW300-N2E2 1.0 Pf6N2E2_4154 diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s) 1.0 Pf6N2E2_149 Inner membrane component of tripartite multidrug resistance system 0.34 4
Pseudomonas fluorescens FW300-N2C3 0.93 AO356_11425 diguanylate phosphodiesterase 0.99 AO356_01025 multidrug resistance protein B low > 104
Pseudomonas sp. RS175 0.89 PFR28_04632 putative cyclic di-GMP phosphodiesterase PdeB 0.98 PFR28_02747 Multidrug export protein EmrB low > 88
Pseudomonas fluorescens GW456-L13 0.83 PfGW456L13_586 Rtn protein 0.89 PfGW456L13_2606 Inner membrane component of tripartite multidrug resistance system low > 87
Pseudomonas fluorescens FW300-N1B4 0.82 Pf1N1B4_1883 diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s) 0.96 Pf1N1B4_4002 Inner membrane component of tripartite multidrug resistance system low > 87
Pseudomonas fluorescens FW300-N2E3 0.81 AO353_10970 diguanylate phosphodiesterase 0.95 AO353_27840 multidrug resistance protein B low > 101
Pseudomonas putida KT2440 0.70 PP_0131 putative membrane-anchored phosphodiesterase 0.90 PP_3548 multidrug efflux transport system - permease subunit low > 96
Pseudomonas sp. S08-1 0.52 OH686_12165 Rtn protein 0.23 OH686_04570 Inner-membrane proton/drug antiporter (MSF type) of tripartite multidrug efflux system low > 80
Enterobacter sp. TBS_079 0.26 MPMX20_01055 putative cyclic di-GMP phosphodiesterase PdeB 0.49 MPMX20_03564 Multidrug export protein EmrB low > 85
Enterobacter asburiae PDN3 0.25 EX28DRAFT_2505 Predicted signal transduction protein containing sensor and EAL domains 0.50 EX28DRAFT_2769 drug resistance transporter, EmrB/QacA subfamily 0.70 6
Xanthomonas campestris pv. campestris strain 8004 0.25 Xcc-8004.4919.1 FIG01210508: hypothetical protein 0.61 Xcc-8004.3524.1 Inner membrane component of tripartite multidrug resistance system low > 74
Rhizobium sp. OAE497 0.25 ABIE40_RS05110 EAL domain-containing protein 0.28 ABIE40_RS21925 DHA2 family efflux MFS transporter permease subunit low > 107
Escherichia coli Nissle 1917 0.24 ECOLIN_RS02725 cyclic-guanylate-specific phosphodiesterase PdeB 0.48 ECOLIN_RS14970 multidrug efflux MFS transporter permease subunit EmrB low > 55
Escherichia coli ECOR38 0.24 HEPCGN_06845 pdeB cyclic-guanylate-specific phosphodiesterase PdeB 0.49 HEPCGN_19970 emrB multidrug efflux MFS transporter permease subunit EmrB low > 87
Escherichia coli BW25113 0.24 b0457 ylaB orf, hypothetical protein (VIMSS) 0.48 b2686 emrB multidrug efflux system protein (NCBI) low > 76
Escherichia coli ECRC100 0.24 OKFHMN_08230 pdeB cyclic-guanylate-specific phosphodiesterase PdeB 0.48 OKFHMN_20775 emrB multidrug efflux MFS transporter permease subunit EmrB 0.80 39
Escherichia coli ECOR27 0.24 NOLOHH_01165 pdeB cyclic-guanylate-specific phosphodiesterase PdeB 0.48 NOLOHH_12615 emrB multidrug efflux MFS transporter permease subunit EmrB low > 75
Escherichia coli ECRC102 0.24 NIAGMN_06285 pdeB cyclic-guanylate-specific phosphodiesterase PdeB 0.48 NIAGMN_18545 emrB multidrug efflux MFS transporter permease subunit EmrB — —
Escherichia coli ECRC99 0.24 KEDOAH_19735 pdeB cyclic-guanylate-specific phosphodiesterase PdeB 0.48 KEDOAH_07360 emrB multidrug efflux MFS transporter permease subunit EmrB — —
Escherichia coli ECRC101 0.24 MCAODC_27455 pdeB cyclic-guanylate-specific phosphodiesterase PdeB 0.48 MCAODC_11300 emrB multidrug efflux MFS transporter permease subunit EmrB low > 87
Escherichia coli ECRC62 0.24 BNILDI_22580 pdeB cyclic-guanylate-specific phosphodiesterase PdeB 0.48 BNILDI_11175 emrB multidrug efflux MFS transporter permease subunit EmrB low > 75
Escherichia coli HS(pFamp)R (ATCC 700891) 0.24 OHPLBJKB_03217 putative cyclic di-GMP phosphodiesterase PdeB 0.48 OHPLBJKB_01047 Multidrug export protein EmrB low > 73
Escherichia fergusonii Becca 0.24 EFB2_03601 putative cyclic di-GMP phosphodiesterase PdeB 0.48 EFB2_01242 Multidrug export protein EmrB low > 86
Escherichia coli ECRC98 0.24 JDDGAC_11885 pdeB cyclic-guanylate-specific phosphodiesterase PdeB 0.48 JDDGAC_24440 emrB multidrug efflux MFS transporter permease subunit EmrB low > 86
Klebsiella michiganensis M5al 0.24 BWI76_RS06685 cyclic diguanylate phosphodiesterase (EAL) domain-containing protein 0.49 BWI76_RS22100 multidrug effux MFS transporter subunit EmrB low > 92
Escherichia coli BL21 0.24 ECD_00408 putative membrane-anchored cyclic-di-GMP phosphodiesterase 0.48 ECD_02541 multidrug efflux system protein low > 61
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.24 GFF4372 Uncharacterized protein ylaB 0.49 GFF1593 Multidrug resistance protein B low > 78
Pectobacterium carotovorum WPP14 0.18 HER17_RS16195 EAL domain-containing protein 0.50 HER17_RS04460 multidrug efflux MFS transporter permease subunit EmrB low > 75
Bosea sp. OAE506 0.16 ABIE41_RS16245 EAL domain-containing protein 0.22 ABIE41_RS08465 DHA2 family efflux MFS transporter permease subunit low > 77

Not shown: 1 genomes with orthologs for Pf6N2E2_4154 only; 54 genomes with orthologs for Pf6N2E2_149 only