| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
| Vibrio cholerae E7946 ATCC 55056 | 1.0 | CSW01_17690 | | NADH-dependent alcohol dehydrogenase | 1.0 | CSW01_15345 | | XRE family transcriptional regulator | 0.65 | 3 |
| Shewanella sp. ANA-3 | 0.48 | Shewana3_0261 | | iron-containing alcohol dehydrogenase (RefSeq) | 0.14 | Shewana3_3100 | | XRE family transcriptional regulator (RefSeq) | low | > 73 |
| Shewanella oneidensis MR-1 | 0.48 | SO4469 | | alcohol dehydrogenase, iron-containing (NCBI ptt file) | 0.13 | SO1265 | | transcriptional regulator, putative (NCBI ptt file) | low | > 76 |
| Escherichia coli ECOR38 | 0.46 | HEPCGN_17810 | yqhD | alcohol dehydrogenase | 0.14 | HEPCGN_25765 | puuR | HTH-type transcriptional regulator PuuR | low | > 88 |
| Escherichia coli BW25113 | 0.46 | b3011 | yqhD | alcohol dehydrogenase, NAD(P)-dependent (NCBI) | 0.14 | b1299 | puuR | DNA-binding transcriptional repressor (NCBI) | low | > 76 |
| Escherichia coli HS(pFamp)R (ATCC 700891) | 0.46 | OHPLBJKB_00690 | | Alcohol dehydrogenase YqhD | 0.14 | OHPLBJKB_02383 | | HTH-type transcriptional regulator PuuR | low | > 74 |
| Escherichia coli ECRC62 | 0.46 | BNILDI_00795 | yqhD | alcohol dehydrogenase | 0.14 | BNILDI_18270 | puuR | HTH-type transcriptional regulator PuuR | low | > 75 |
| Escherichia coli BL21 | 0.46 | ECD_02884 | | aldehyde reductase, NADPH-dependent | 0.14 | ECD_01276 | | repressor for the divergent puu operons, putrescine inducible | low | > 61 |
| Escherichia coli ECOR27 | 0.46 | NOLOHH_10720 | yqhD | alcohol dehydrogenase | 0.14 | NOLOHH_20120 | puuR | HTH-type transcriptional regulator PuuR | low | > 76 |
| Pseudomonas putida KT2440 | 0.46 | PP_2492 | | alcohol dehydrogenase, NAD(P)-dependent | 0.22 | PP_2245 | | Transcriptional regulator, Cro/CI family | low | > 96 |
| Escherichia coli ECRC100 | 0.45 | OKFHMN_18945 | yqhD | alcohol dehydrogenase | 0.14 | OKFHMN_02435 | puuR | HTH-type transcriptional regulator PuuR | low | > 79 |
| Escherichia coli ECRC98 | 0.45 | JDDGAC_22580 | yqhD | alcohol dehydrogenase | 0.14 | JDDGAC_04980 | puuR | HTH-type transcriptional regulator PuuR | low | > 87 |
| Escherichia coli ECRC101 | 0.45 | MCAODC_09460 | yqhD | alcohol dehydrogenase | 0.14 | MCAODC_15835 | puuR | HTH-type transcriptional regulator PuuR | low | > 87 |
| Escherichia coli ECRC99 | 0.45 | KEDOAH_09200 | yqhD | alcohol dehydrogenase | 0.14 | KEDOAH_26340 | puuR | HTH-type transcriptional regulator PuuR | — | — |
| Escherichia coli ECRC102 | 0.45 | NIAGMN_16710 | yqhD | alcohol dehydrogenase | 0.14 | NIAGMN_26605 | puuR | HTH-type transcriptional regulator PuuR | low | > 80 |
| Klebsiella pneumoniae MKP103 | 0.45 | KDGMDA_05135 | | alcohol dehydrogenase | 0.14 | KDGMDA_18340 | | HTH-type transcriptional regulator PuuR | low | > 95 |
| Klebsiella michiganensis M5al | 0.45 | BWI76_RS24300 | | NADH-dependent alcohol dehydrogenase | 0.14 | BWI76_RS10700 | | XRE family transcriptional regulator | low | > 92 |
| Parabacteroides merdae CL09T00C40 | 0.44 | HMPREF1078_RS01985 | | iron-containing alcohol dehydrogenase | 0.15 | HMPREF1078_RS17570 | | XRE family transcriptional regulator | low | > 61 |
| Enterobacter asburiae PDN3 | 0.44 | EX28DRAFT_3049 | | Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family | 0.15 | EX28DRAFT_1500 | | Predicted transcriptional regulators | low | > 76 |
| Echinicola vietnamensis KMM 6221, DSM 17526 | 0.41 | Echvi_1168 | | Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family | 0.13 | Echvi_4557 | | Predicted transcriptional regulators | low | > 79 |
| Desulfovibrio vulgaris Hildenborough JW710 | 0.41 | DVU2201 | b3011 | alcohol dehydrogenase, iron-containing (TIGR) | 0.13 | DVU2251 | | DNA-binding protein (TIGR) | low | > 55 |
| Bacteroides ovatus ATCC 8483 | 0.39 | BACOVA_03776 | | alcohol dehydrogenase, iron-dependent | 0.16 | BACOVA_01081 | | hypothetical protein | low | > 96 |
| Bacteroides thetaiotaomicron VPI-5482 | 0.39 | BT0535 | | iron-containing alcohol dehydrogenase (NCBI ptt file) | 0.17 | BT2783 | | transcriptional regulator (NCBI ptt file) | low | > 81 |
| Phocaeicola vulgatus CL09T03C04 | 0.38 | HMPREF1058_RS00185 | | iron-containing alcohol dehydrogenase | 0.13 | HMPREF1058_RS17685 | | helix-turn-helix transcriptional regulator | low | > 67 |
| Phocaeicola dorei CL03T12C01 | 0.38 | ABI39_RS01085 | | iron-containing alcohol dehydrogenase | 0.13 | ABI39_RS13885 | | helix-turn-helix transcriptional regulator | low | > 72 |
| Bacteroides stercoris CC31F | 0.28 | HMPREF1181_RS04790 | | iron-containing alcohol dehydrogenase | 0.16 | HMPREF1181_RS01200 | | helix-turn-helix transcriptional regulator | low | > 56 |
Not shown: 19 genomes with orthologs for CSW01_17690 only; 35 genomes with orthologs for CSW01_15345 only