Conservation of cofitness between BWI76_RS01545 and BWI76_RS20390 in Klebsiella michiganensis M5al

30 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Klebsiella michiganensis M5al 1.0 BWI76_RS01545 thiamine biosynthesis protein ThiS 1.0 BWI76_RS20390 erythronate-4-phosphate dehydrogenase 0.35 12
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.81 GFF4200 Sulfur carrier protein adenylyltransferase ThiF 0.86 GFF1936 Erythronate-4-phosphate dehydrogenase (EC 1.1.1.290) low > 78
Enterobacter sp. TBS_079 0.81 MPMX20_00215 Sulfur carrier protein ThiS adenylyltransferase 0.83 MPMX20_03255 Erythronate-4-phosphate dehydrogenase 0.45 2
Enterobacter asburiae PDN3 0.80 EX28DRAFT_4534 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 0.84 EX28DRAFT_0284 Phosphoglycerate dehydrogenase and related dehydrogenases 0.73 2
Escherichia coli ECRC62 0.76 BNILDI_05995 thiF thiazole biosynthesis adenylyltransferase ThiF 0.82 BNILDI_13215 pdxB 4-phosphoerythronate dehydrogenase PdxB 0.89 14
Escherichia coli BL21 0.76 ECD_03869 adenylyltransferase, modifies ThiS C-terminus 0.83 ECD_02245 erythronate-4-phosphate dehydrogenase 0.54 22
Escherichia coli HS(pFamp)R (ATCC 700891) 0.76 OHPLBJKB_04058 Sulfur carrier protein ThiS adenylyltransferase 0.83 OHPLBJKB_01385 Erythronate-4-phosphate dehydrogenase low > 73
Escherichia coli BW25113 0.76 b3992 thiF thiamin biosynthesis, thiazole moiety (VIMSS) 0.83 b2320 pdxB erythronate-4-phosphate dehydrogenase (NCBI) 0.68 6
Escherichia coli ECOR27 0.76 NOLOHH_05530 thiF thiazole biosynthesis adenylyltransferase ThiF 0.82 NOLOHH_14295 pdxB 4-phosphoerythronate dehydrogenase PdxB low > 75
Escherichia coli ECOR38 0.76 HEPCGN_12020 thiF thiazole biosynthesis adenylyltransferase ThiF 0.81 HEPCGN_21865 pdxB 4-phosphoerythronate dehydrogenase PdxB 0.88 10
Escherichia coli ECRC100 0.76 OKFHMN_13385 thiF thiazole biosynthesis adenylyltransferase ThiF 0.82 OKFHMN_22660 pdxB 4-phosphoerythronate dehydrogenase PdxB low > 80
Escherichia coli ECRC99 0.76 KEDOAH_14775 thiF thiazole biosynthesis adenylyltransferase ThiF 0.82 KEDOAH_05535 pdxB 4-phosphoerythronate dehydrogenase PdxB — —
Escherichia coli ECRC98 0.76 JDDGAC_17010 thiF thiazole biosynthesis adenylyltransferase ThiF 0.82 JDDGAC_26620 pdxB 4-phosphoerythronate dehydrogenase PdxB low > 86
Escherichia fergusonii Becca 0.76 EFB2_04619 Sulfur carrier protein ThiS adenylyltransferase 0.83 EFB2_01538 Erythronate-4-phosphate dehydrogenase low > 86
Escherichia coli ECRC101 0.76 MCAODC_03885 thiF thiazole biosynthesis adenylyltransferase ThiF 0.82 MCAODC_13700 pdxB 4-phosphoerythronate dehydrogenase PdxB 0.88 7
Escherichia coli ECRC102 0.76 NIAGMN_11135 thiF thiazole biosynthesis adenylyltransferase ThiF 0.82 NIAGMN_20435 pdxB 4-phosphoerythronate dehydrogenase PdxB — —
Escherichia coli Nissle 1917 0.75 ECOLIN_RS23030 thiazole biosynthesis adenylyltransferase ThiF 0.83 ECOLIN_RS13445 4-phosphoerythronate dehydrogenase PdxB 0.56 22
Dickeya dadantii 3937 0.68 DDA3937_RS01165 HesA/MoeB/ThiF family protein 0.75 DDA3937_RS14475 4-phosphoerythronate dehydrogenase PdxB low > 74
Erwinia tracheiphila SCR3 0.66 LU632_RS00960 HesA/MoeB/ThiF family protein 0.73 LU632_RS07815 DUF3410 domain-containing protein — —
Serratia liquefaciens MT49 0.66 IAI46_01310 HesA/MoeB/ThiF family protein 0.72 IAI46_17850 4-phosphoerythronate dehydrogenase PdxB low > 86
Dickeya dianthicola ME23 0.65 DZA65_RS01205 HesA/MoeB/ThiF family protein 0.74 DZA65_RS15380 4-phosphoerythronate dehydrogenase PdxB low > 75
Dickeya dianthicola 67-19 0.64 HGI48_RS01160 HesA/MoeB/ThiF family protein 0.70 HGI48_RS14445 4-phosphoerythronate dehydrogenase PdxB low > 71
Pectobacterium carotovorum WPP14 0.61 HER17_RS20390 HesA/MoeB/ThiF family protein 0.70 HER17_RS06980 4-phosphoerythronate dehydrogenase PdxB low > 75
Rahnella sp. WP5 0.59 EX31_RS16805 HesA/MoeB/ThiF family protein 0.72 EX31_RS19610 4-phosphoerythronate dehydrogenase PdxB low > 89
Kangiella aquimarina DSM 16071 0.42 B158DRAFT_1711 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 0.40 B158DRAFT_1308 4-phosphoerythronate dehydrogenase (EC 1.1.1.290) — —
Vibrio cholerae E7946 ATCC 55056 0.40 CSW01_00345 thiazole biosynthesis adenylyltransferase ThiF 0.48 CSW01_10525 DUF3410 domain-containing protein — —
Shewanella loihica PV-4 0.39 Shew_2094 UBA/THIF-type NAD/FAD binding protein (RefSeq) 0.41 Shew_2309 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding (RefSeq) — —
Shewanella oneidensis MR-1 0.34 SO2443 thiF thiF protein, putative (NCBI ptt file) 0.43 SO3071 pdxB erythronate-4-phosphate dehydrogenase (NCBI ptt file) — —
Bacteroides ovatus ATCC 8483 0.32 BACOVA_02356 ThiF family protein 0.33 BACOVA_01953 4-phosphoerythronate dehydrogenase 0.63 85
Bacteroides thetaiotaomicron VPI-5482 0.32 BT0648 molybdopterin biosynthesis protein (NCBI ptt file) 0.32 BT3361 erythronate-4-phosphate dehydrogenase (NCBI ptt file) 0.37 67
Bacteroides stercoris CC31F 0.31 HMPREF1181_RS14695 HesA/MoeB/ThiF family protein 0.34 HMPREF1181_RS02440 4-phosphoerythronate dehydrogenase PdxB — —

Not shown: 14 genomes with orthologs for BWI76_RS01545 only; 23 genomes with orthologs for BWI76_RS20390 only