Conservation of cofitness between NOLOHH_20595 and NOLOHH_13650 in Escherichia coli ECOR27

23 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli ECOR27 1.0 NOLOHH_20595 sirB1 invasion regulator SirB1 1.0 NOLOHH_13650 acrD multidrug efflux RND transporter permease AcrD 0.57 19
Escherichia coli ECRC99 1.00 KEDOAH_25460 sirB1 invasion regulator SirB1 1.00 KEDOAH_06250 acrD multidrug efflux RND transporter permease AcrD — —
Escherichia coli ECRC102 1.00 NIAGMN_27770 sirB1 invasion regulator SirB1 1.00 NIAGMN_19740 acrD multidrug efflux RND transporter permease AcrD — —
Escherichia coli BL21 1.00 ECD_01189 transglutaminase-like TPR-repeat protein 1.00 ECD_02361 aminoglycoside/multidrug efflux system low > 61
Escherichia coli ECRC100 1.00 OKFHMN_28465 sirB1 invasion regulator SirB1 1.00 OKFHMN_21970 acrD multidrug efflux RND transporter permease AcrD low > 80
Escherichia coli ECRC62 1.00 BNILDI_18750 sirB1 invasion regulator SirB1 1.00 BNILDI_12460 acrD multidrug efflux RND transporter permease AcrD low > 75
Escherichia coli ECOR38 1.00 HEPCGN_24930 sirB1 invasion regulator SirB1 1.00 HEPCGN_21140 acrD multidrug efflux RND transporter permease AcrD low > 87
Escherichia coli ECRC101 1.00 MCAODC_21795 sirB1 invasion regulator SirB1 1.00 MCAODC_12500 acrD multidrug efflux RND transporter permease AcrD low > 87
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_02473 hypothetical protein 1.00 OHPLBJKB_01261 Multidrug efflux pump subunit AcrB low > 73
Escherichia coli ECRC98 1.00 JDDGAC_06110 sirB1 invasion regulator SirB1 1.00 JDDGAC_25915 acrD multidrug efflux RND transporter permease AcrD low > 86
Escherichia coli BW25113 1.00 b1214 ychA predicted transcriptional regulator (NCBI) 1.00 b2470 acrD aminoglycoside/multidrug efflux system (NCBI) low > 76
Escherichia fergusonii Becca 1.00 EFB2_02713 hypothetical protein 1.00 EFB2_01418 Multidrug efflux pump subunit AcrB low > 86
Escherichia coli Nissle 1917 0.99 ECOLIN_RS07335 invasion regulator SirB1 1.00 ECOLIN_RS14090 multidrug efflux RND transporter permease AcrD low > 55
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.86 GFF2771 FIG002708: Protein SirB1 0.95 GFF2188 RND efflux system, inner membrane transporter CmeB low > 78
Enterobacter asburiae PDN3 0.82 EX28DRAFT_0833 Uncharacterized conserved protein 0.92 EX28DRAFT_0191 The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family low > 76
Enterobacter sp. TBS_079 0.82 MPMX20_02633 hypothetical protein 0.92 MPMX20_03331 Multidrug efflux pump subunit AcrB low > 85
Klebsiella michiganensis M5al 0.78 BWI76_RS17420 hypothetical protein 0.92 BWI76_RS20860 aminoglycoside/multidrug transporter subunit AcrD low > 92
Pectobacterium carotovorum WPP14 0.68 HER17_RS10495 invasion regulator SirB1 0.81 HER17_RS01560 multidrug efflux RND transporter permease AcrD low > 75
Pantoea sp. MT58 0.65 IAI47_11255 tetratricopeptide repeat-containing protein 0.82 IAI47_05310 multidrug efflux RND transporter permease AcrD — —
Serratia liquefaciens MT49 0.64 IAI46_10295 tetratricopeptide repeat-containing protein 0.83 IAI46_18690 multidrug efflux RND transporter permease AcrD low > 86
Rahnella sp. WP5 0.63 EX31_RS07300 tetratricopeptide repeat-containing protein 0.79 EX31_RS22805 multidrug efflux RND transporter permease AcrD low > 89
Vibrio cholerae E7946 ATCC 55056 0.34 CSW01_10830 hypothetical protein 0.24 CSW01_00850 multidrug resistance protein low > 62
Herbaspirillum seropedicae SmR1 0.14 HSERO_RS06985 transglutaminase 0.59 HSERO_RS23055 multidrug transporter low > 78
Hydrogenophaga sp. GW460-11-11-14-LB1 0.13 GFF3424 Protein sirB1 0.52 GFF5685 RND efflux system, inner membrane transporter CmeB low > 90

Not shown: 23 genomes with orthologs for NOLOHH_20595 only; 14 genomes with orthologs for NOLOHH_13650 only