Conservation of cofitness between HER17_RS21350 and HER17_RS16195 in Pectobacterium carotovorum WPP14

23 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Pectobacterium carotovorum WPP14 1.0 HER17_RS21350 EAL domain-containing protein 1.0 HER17_RS16195 EAL domain-containing protein 0.56 10
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.31 GFF4237 diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s) 0.25 GFF4372 Uncharacterized protein ylaB low > 78
Escherichia coli ECRC98 0.30 JDDGAC_08140 eAL EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant) 0.27 JDDGAC_11885 pdeB cyclic-guanylate-specific phosphodiesterase PdeB low > 86
Escherichia coli ECRC102 0.30 NIAGMN_23805 eAL EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant) 0.27 NIAGMN_06285 pdeB cyclic-guanylate-specific phosphodiesterase PdeB — —
Escherichia coli ECRC101 0.30 MCAODC_23905 eAL EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant) 0.27 MCAODC_27455 pdeB cyclic-guanylate-specific phosphodiesterase PdeB low > 87
Escherichia coli ECRC99 0.30 KEDOAH_23215 eAL EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant) 0.27 KEDOAH_19735 pdeB cyclic-guanylate-specific phosphodiesterase PdeB — —
Escherichia coli ECRC100 0.30 OKFHMN_04530 eAL EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant) 0.27 OKFHMN_08230 pdeB cyclic-guanylate-specific phosphodiesterase PdeB — —
Pseudomonas fluorescens FW300-N2E2 0.21 Pf6N2E2_452 Rtn protein 0.17 Pf6N2E2_4154 diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s) low > 103
Enterobacter sp. TBS_079 0.21 MPMX20_02720 putative cyclic di-GMP phosphodiesterase PdeD 0.23 MPMX20_01055 putative cyclic di-GMP phosphodiesterase PdeB low > 85
Pseudomonas fluorescens FW300-N1B4 0.21 Pf1N1B4_5006 Rtn protein 0.17 Pf1N1B4_1883 diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s) low > 87
Pseudomonas fluorescens GW456-L13 0.21 PfGW456L13_2932 Rtn protein 0.17 PfGW456L13_586 Rtn protein low > 87
Pseudomonas fluorescens FW300-N2C3 0.21 AO356_22830 diguanylate phosphodiesterase 0.17 AO356_11425 diguanylate phosphodiesterase low > 104
Klebsiella michiganensis M5al 0.21 BWI76_RS17880 c-di-GMP phosphodiesterase 0.24 BWI76_RS06685 cyclic diguanylate phosphodiesterase (EAL) domain-containing protein 0.20 46
Enterobacter asburiae PDN3 0.20 EX28DRAFT_1790 FOG: EAL domain 0.24 EX28DRAFT_2505 Predicted signal transduction protein containing sensor and EAL domains low > 76
Escherichia fergusonii Becca 0.20 EFB2_01680 putative cyclic di-GMP phosphodiesterase PdeN 0.26 EFB2_03601 putative cyclic di-GMP phosphodiesterase PdeB low > 86
Escherichia coli ECOR38 0.20 HEPCGN_22660 pdeN cyclic di-GMP phosphodiesterase 0.27 HEPCGN_06845 pdeB cyclic-guanylate-specific phosphodiesterase PdeB low > 87
Escherichia coli ECOR27 0.20 NOLOHH_14970 pdeN cyclic di-GMP phosphodiesterase 0.27 NOLOHH_01165 pdeB cyclic-guanylate-specific phosphodiesterase PdeB low > 75
Escherichia coli HS(pFamp)R (ATCC 700891) 0.20 OHPLBJKB_01533 putative cyclic di-GMP phosphodiesterase PdeN 0.26 OHPLBJKB_03217 putative cyclic di-GMP phosphodiesterase PdeB low > 73
Escherichia coli ECRC62 0.20 BNILDI_13890 pdeN cyclic di-GMP phosphodiesterase 0.27 BNILDI_22580 pdeB cyclic-guanylate-specific phosphodiesterase PdeB 0.76 4
Escherichia coli BW25113 0.20 b2176 rtn hypothetical protein (NCBI) 0.26 b0457 ylaB orf, hypothetical protein (VIMSS) low > 76
Escherichia coli Nissle 1917 0.20 ECOLIN_RS12725 cyclic di-GMP phosphodiesterase 0.27 ECOLIN_RS02725 cyclic-guanylate-specific phosphodiesterase PdeB low > 55
Escherichia coli BL21 0.20 ECD_02106 resistance protein for phages lambda and N4, putative membrane-anchored cyclic-di-GMP phosphodiesterase 0.26 ECD_00408 putative membrane-anchored cyclic-di-GMP phosphodiesterase 0.64 31
Pseudomonas fluorescens FW300-N2E3 0.19 AO353_26940 diguanylate phosphodiesterase 0.17 AO353_10970 diguanylate phosphodiesterase low > 101
Pseudomonas putida KT2440 0.19 PP_3435 conserved protein of unknown function 0.19 PP_0131 putative membrane-anchored phosphodiesterase low > 96

Not shown: 13 genomes with orthologs for HER17_RS21350 only; 7 genomes with orthologs for HER17_RS16195 only