Conservation of cofitness between BWI76_RS06780 and BWI76_RS19765 in Klebsiella michiganensis M5al

26 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Klebsiella michiganensis M5al 1.0 BWI76_RS06780 MexE family multidrug efflux RND transporter periplasmic adaptor subunit 1.0 BWI76_RS19765 membrane protein 0.41 13
Enterobacter sp. TBS_079 0.87 MPMX20_01065 Multidrug efflux pump subunit AcrA 0.69 MPMX20_03140 Lipid A 1-diphosphate synthase low > 85
Enterobacter asburiae PDN3 0.84 EX28DRAFT_2495 RND family efflux transporter, MFP subunit 0.73 EX28DRAFT_0387 Membrane-associated phospholipid phosphatase low > 76
Escherichia coli ECRC98 0.83 JDDGAC_11850 acrA multidrug efflux RND transporter periplasmic adaptor subunit AcrA 0.73 JDDGAC_27365 lpxT Kdo(2)-lipid A phosphotransferase low > 86
Escherichia coli ECRC100 0.83 OKFHMN_08200 acrA multidrug efflux RND transporter periplasmic adaptor subunit AcrA 0.73 OKFHMN_23405 lpxT Kdo(2)-lipid A phosphotransferase low > 80
Escherichia coli BW25113 0.83 b0463 acrA multidrug efflux system (NCBI) 0.73 b2174 b2174 orf, hypothetical protein (VIMSS) 0.36 13
Escherichia coli ECRC101 0.83 MCAODC_27425 acrA multidrug efflux RND transporter periplasmic adaptor subunit AcrA 0.73 MCAODC_14455 lpxT Kdo(2)-lipid A phosphotransferase low > 87
Escherichia coli ECRC102 0.83 NIAGMN_06255 acrA multidrug efflux RND transporter periplasmic adaptor subunit AcrA 0.73 NIAGMN_21170 lpxT Kdo(2)-lipid A phosphotransferase — —
Escherichia coli HS(pFamp)R (ATCC 700891) 0.83 OHPLBJKB_03211 Multidrug efflux pump subunit AcrA 0.72 OHPLBJKB_01535 Lipid A 1-diphosphate synthase low > 73
Escherichia coli ECOR27 0.83 NOLOHH_01135 acrA multidrug efflux RND transporter periplasmic adaptor subunit AcrA 0.73 NOLOHH_14980 lpxT Kdo(2)-lipid A phosphotransferase low > 75
Escherichia coli ECRC99 0.83 KEDOAH_19765 acrA multidrug efflux RND transporter periplasmic adaptor subunit AcrA 0.73 KEDOAH_04780 lpxT Kdo(2)-lipid A phosphotransferase — —
Escherichia coli BL21 0.83 ECD_00414 multidrug efflux system 0.72 ECD_02104 lipid A 1-diphosphate synthase; undecaprenyl pyrophosphate:lipid A 1-phosphate phosphotransferase low > 61
Escherichia coli ECRC62 0.83 BNILDI_22550 acrA multidrug efflux RND transporter periplasmic adaptor subunit AcrA 0.73 BNILDI_13900 lpxT Kdo(2)-lipid A phosphotransferase low > 75
Escherichia coli ECOR38 0.82 HEPCGN_06815 acrA multidrug efflux RND transporter periplasmic adaptor subunit AcrA 0.73 HEPCGN_22670 lpxT Kdo(2)-lipid A phosphotransferase low > 87
Escherichia fergusonii Becca 0.82 EFB2_03595 Multidrug efflux pump subunit AcrA 0.73 EFB2_01682 Lipid A 1-diphosphate synthase low > 86
Escherichia coli Nissle 1917 0.82 ECOLIN_RS02755 multidrug efflux RND transporter periplasmic adaptor subunit AcrA 0.72 ECOLIN_RS12715 Kdo(2)-lipid A phosphotransferase — —
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.78 GFF4380 Membrane fusion protein of RND family multidrug efflux pump 0.71 GFF3762 Putative membrane protein low > 78
Pantoea sp. MT58 0.74 IAI47_14510 efflux RND transporter periplasmic adaptor subunit 0.54 IAI47_06630 phosphatase PAP2 family protein low > 76
Rahnella sp. WP5 0.74 EX31_RS22475 efflux RND transporter periplasmic adaptor subunit 0.59 EX31_RS19115 phosphatase PAP2 family protein low > 89
Serratia liquefaciens MT49 0.74 IAI46_05190 multidrug efflux RND transporter periplasmic adaptor subunit SdeX 0.61 IAI46_17300 phosphatase PAP2 family protein low > 86
Dickeya dadantii 3937 0.71 DDA3937_RS05740 efflux RND transporter periplasmic adaptor subunit 0.56 DDA3937_RS09200 phosphatase PAP2 family protein low > 74
Pectobacterium carotovorum WPP14 0.68 HER17_RS15735 efflux RND transporter periplasmic adaptor subunit 0.59 HER17_RS12890 phosphatase PAP2 family protein low > 75
Pseudomonas stutzeri RCH2 0.48 Psest_0309 RND family efflux transporter, MFP subunit 0.18 Psest_3990 PAP2 superfamily. low > 67
Pseudomonas fluorescens SBW25 0.48 PFLU_RS06810 efflux RND transporter periplasmic adaptor subunit 0.16 PFLU_RS01310 phosphatase PAP2 family protein low > 109
Pseudomonas fluorescens SBW25-INTG 0.48 PFLU_RS06810 efflux RND transporter periplasmic adaptor subunit 0.16 PFLU_RS01310 phosphatase PAP2 family protein 0.28 62
Pseudomonas simiae WCS417 0.48 PS417_06775 antibiotic transporter 0.14 PS417_01200 phosphoesterase low > 88
Pseudomonas putida KT2440 0.48 PP_1386 Probable efflux pump periplasmic linker TtgA 0.14 PP_0251 conserved membrane protein of unknown function 0.15 91

Not shown: 47 genomes with orthologs for BWI76_RS06780 only; 0 genomes with orthologs for BWI76_RS19765 only