Conservation of cofitness between BWI76_RS22705 and BWI76_RS04665 in Klebsiella michiganensis M5al

16 genomes with putative orthologs of both genes

Organism	Ratio1	Gene1	Name1	Description1	Ratio2	Gene2	Name2	Description2	Cofit	Rank
Klebsiella michiganensis M5al	1.0	BWI76_RS22705		siroheme synthase	1.0	BWI76_RS04665		3-isopropylmalate dehydratase small subunit	0.61	16
Enterobacter asburiae PDN3	0.71	EX28DRAFT_2849		uroporphyrin-III C-methyltransferase	0.92	EX28DRAFT_3667		3-isopropylmalate dehydratase, small subunit	0.71	35
Enterobacter sp. TBS_079	0.70	MPMX20_03639		Siroheme synthase	0.93	MPMX20_00766		3-isopropylmalate dehydratase small subunit 1	0.24	58
Pantoea sp. MT58	0.63	IAI47_04175		uroporphyrinogen-III C-methyltransferase	0.83	IAI47_16015		3-isopropylmalate dehydratase small subunit	0.85	19
Pectobacterium carotovorum WPP14	0.62	HER17_RS04280		siroheme synthase CysG	0.84	HER17_RS03070		3-isopropylmalate dehydratase small subunit	0.87	41
Erwinia tracheiphila SCR3	0.62	LU632_RS06420	cysG	siroheme synthase CysG	0.74	LU632_RS02865	leuD	3-isopropylmalate dehydratase small subunit	low	> 74
Serratia liquefaciens MT49	0.62	IAI46_03710		uroporphyrinogen-III C-methyltransferase	0.84	IAI46_03340		3-isopropylmalate dehydratase small subunit	low	> 86
Rahnella sp. WP5	0.62	EX31_RS07885		uroporphyrinogen-III C-methyltransferase	0.84	EX31_RS03695		3-isopropylmalate dehydratase small subunit	0.85	44
Dickeya dadantii 3937	0.59	DDA3937_RS16930		uroporphyrinogen-III C-methyltransferase	0.84	DDA3937_RS18130		3-isopropylmalate dehydratase small subunit	low	> 74
Dickeya dianthicola ME23	0.59	DZA65_RS18075		uroporphyrinogen-III C-methyltransferase	0.84	DZA65_RS19215		3-isopropylmalate dehydratase small subunit	0.72	44
Dickeya dianthicola 67-19	0.59	HGI48_RS17000		uroporphyrinogen-III C-methyltransferase	0.83	HGI48_RS18070		3-isopropylmalate dehydratase small subunit	0.68	63
Rhodopseudomonas palustris CGA009	0.33	TX73_021850		siroheme synthase CysG	0.51	TX73_001215		3-isopropylmalate dehydratase small subunit	—	—
Agrobacterium fabrum C58	0.32	Atu1454		siroheme synthase	0.49	Atu2790		3-isopropylmalate dehydratase, small subunit	0.83	23
Rhizobium sp. OAE497	0.30	ABIE40_RS09140		siroheme synthase CysG	0.48	ABIE40_RS19040		3-isopropylmalate dehydratase small subunit	0.93	9
Dinoroseobacter shibae DFL-12	0.30	Dshi_1671		uroporphyrin-III C-methyltransferase (RefSeq)	0.51	Dshi_0083		3-isopropylmalate dehydratase, small subunit (RefSeq)	low	> 64
Bosea sp. OAE506	0.28	ABIE41_RS15910		siroheme synthase CysG	0.47	ABIE41_RS11640		3-isopropylmalate dehydratase small subunit	—	—
Mycobacterium tuberculosis H37Rv	0.18	Rv2847c		Possible multifunctional enzyme siroheme synthase CysG: uroporphyrin-III C-methyltransferase (urogen III methylase) (SUMT) (uroporphyrinogen III methylase) (UROM) + precorrin-2 oxidase + ferrochelatase	0.39	Rv2987c		Probable 3-isopropylmalate dehydratase (small subunit) LeuD (isopropylmalate isomerase) (alpha-IPM isomerase) (IPMI)	—	—

Not shown: 0 genomes with orthologs for BWI76_RS22705 only; 82 genomes with orthologs for BWI76_RS04665 only