| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
|---|
| Bacteroides thetaiotaomicron VPI-5482 | 1.0 | BT1911 | | 7-alpha-hydroxysteroid dehydrogenase (NCBI ptt file) | 1.0 | BT3801 | | rteB, two-component system response regulator (NCBI ptt file) | 0.23 | 5 |
| Bacteroides ovatus ATCC 8483 | 0.92 | BACOVA_01473 | | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.89 | BACOVA_03647 | | Sigma-54 interaction domain protein | low | > 94 |
| Acidovorax sp. GW101-3H11 | 0.39 | Ac3H11_2732 | | 3-oxoacyl-[acyl-carrier protein] reductase (EC 1.1.1.100) | 0.35 | Ac3H11_4011 | | Putative sensory histidine kinase YfhA | low | > 79 |
| Pseudomonas fluorescens GW456-L13 | 0.32 | PfGW456L13_3453 | | Short-chain dehydrogenase/reductase SDR | 0.32 | PfGW456L13_1524 | | Two-component sensor CbrB: intrcellular carbon:nitrogen balance | low | > 87 |
| Phocaeicola dorei CL03T12C01 | 0.28 | ABI39_RS19330 | | SDR family oxidoreductase | 0.73 | ABI39_RS02120 | | sigma-54-dependent Fis family transcriptional regulator | low | > 72 |
| Parabacteroides merdae CL09T00C40 | 0.28 | HMPREF1078_RS05050 | | glucose 1-dehydrogenase | 0.63 | HMPREF1078_RS07540 | | sigma-54 dependent transcriptional regulator | low | > 61 |
| Mucilaginibacter yixingensis YX-36 DSM 26809 | 0.28 | ABZR88_RS19550 | | SDR family oxidoreductase | 0.45 | ABZR88_RS00090 | | sigma-54 dependent transcriptional regulator | low | > 71 |
| Echinicola vietnamensis KMM 6221, DSM 17526 | 0.27 | Echvi_3364 | | Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) | 0.47 | Echvi_4656 | | Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains | low | > 79 |
| Alteromonas macleodii MIT1002 | 0.26 | MIT1002_02275 | | 4-formylbenzenesulfonate dehydrogenase TsaC1/TsaC2 | 0.33 | MIT1002_01326 | | Quorum-sensing regulator protein F | low | > 70 |
| Marinobacter adhaerens HP15 | 0.26 | HP15_1707 | | short-chain dehydrogenase/reductase SDR | 0.33 | HP15_328 | | two component, sigma54 specific, transcriptional regulator, Fis family | low | > 73 |
| Escherichia coli ECOR27 | 0.26 | NOLOHH_18115 | hdhA | 7-alpha-hydroxysteroid dehydrogenase | 0.36 | NOLOHH_05465 | zraR | sigma-54-dependent response regulator transcription factor ZraR | low | > 75 |
| Escherichia coli ECRC62 | 0.26 | BNILDI_16905 | hdhA | 7-alpha-hydroxysteroid dehydrogenase | 0.35 | BNILDI_06055 | zraR | sigma-54-dependent response regulator transcription factor ZraR | low | > 75 |
| Escherichia coli BW25113 | 0.26 | b1619 | hdhA | 7-alpha-hydroxysteroid dehydrogenase (NCBI) | 0.36 | b4004 | zraR | fused DNA-binding response regulator in two-component regulatory system with ZraS: response regulator/sigma54 interaction protein (NCBI) | low | > 76 |
| Escherichia coli ECRC100 | 0.26 | OKFHMN_27600 | hdhA | 7-alpha-hydroxysteroid dehydrogenase | 0.35 | OKFHMN_13320 | zraR | sigma-54-dependent response regulator transcription factor ZraR | low | > 80 |
| Escherichia coli ECRC102 | 0.26 | NIAGMN_00475 | hdhA | 7-alpha-hydroxysteroid dehydrogenase | 0.35 | NIAGMN_11070 | zraR | sigma-54-dependent response regulator transcription factor ZraR | — | — |
| Escherichia coli ECOR38 | 0.26 | HEPCGN_05985 | hdhA | 7-alpha-hydroxysteroid dehydrogenase | 0.35 | HEPCGN_11960 | zraR | sigma-54-dependent response regulator transcription factor ZraR | low | > 87 |
| Escherichia coli ECRC98 | 0.26 | JDDGAC_02190 | hdhA | 7-alpha-hydroxysteroid dehydrogenase | 0.35 | JDDGAC_16945 | zraR | sigma-54-dependent response regulator transcription factor ZraR | low | > 86 |
| Escherichia coli Nissle 1917 | 0.26 | ECOLIN_RS09035 | | 7-alpha-hydroxysteroid dehydrogenase | 0.36 | ECOLIN_RS23090 | | sigma-54-dependent response regulator transcription factor ZraR | — | — |
| Escherichia coli BL21 | 0.26 | ECD_01588 | | 7-alpha-hydroxysteroid dehydrogenase, NAD-dependent | 0.35 | ECD_03881 | | fused DNA-binding response regulator in two-component regulatory system with ZraS: response regulator/sigma54 interaction protein | — | — |
| Escherichia coli ECRC101 | 0.26 | MCAODC_17810 | hdhA | 7-alpha-hydroxysteroid dehydrogenase | 0.35 | MCAODC_03820 | zraR | sigma-54-dependent response regulator transcription factor ZraR | low | > 87 |
| Escherichia coli ECRC99 | 0.26 | KEDOAH_00505 | hdhA | 7-alpha-hydroxysteroid dehydrogenase | 0.35 | KEDOAH_14840 | zraR | sigma-54-dependent response regulator transcription factor ZraR | — | — |
| Pseudomonas putida KT2440 | 0.26 | PP_1953 | | Oxidoreductase, short chain dehydrogenase/reductase family | 0.33 | PP_4696 | | Nitrogen regulation protein NR(I) | low | > 96 |
| Escherichia coli HS(pFamp)R (ATCC 700891) | 0.26 | OHPLBJKB_02107 | | 7-alpha-hydroxysteroid dehydrogenase | 0.35 | OHPLBJKB_04045 | | Transcriptional regulatory protein ZraR | low | > 73 |
| Escherichia fergusonii Becca | 0.26 | EFB2_02373 | | 7-alpha-hydroxysteroid dehydrogenase | 0.35 | EFB2_04606 | | Transcriptional regulatory protein ZraR | low | > 86 |
| Rhodanobacter denitrificans MT42 | 0.24 | LRK55_RS13945 | | glucose 1-dehydrogenase | 0.32 | LRK55_RS04800 | | sigma-54 dependent transcriptional regulator | low | > 63 |
| Rhodanobacter denitrificans FW104-10B01 | 0.24 | LRK54_RS14225 | | glucose 1-dehydrogenase | 0.32 | LRK54_RS05020 | | sigma-54 dependent transcriptional regulator | low | > 59 |
Not shown: 12 genomes with orthologs for BT1911 only; 27 genomes with orthologs for BT3801 only