| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
|---|
| Escherichia coli BW25113 | 1.0 | b0871 | poxB | pyruvate dehydrogenase (NCBI) | 1.0 | b3802 | hemY | predicted protoheme IX synthesis protein (NCBI) | 0.24 | 15 |
| Escherichia coli BL21 | 1.00 | ECD_00876 | | pyruvate dehydrogenase, thiamine triphosphate-binding, FAD-binding | 1.00 | ECD_03677 | | putative protoheme IX synthesis protein | low | > 60 |
| Escherichia coli HS(pFamp)R (ATCC 700891) | 1.00 | OHPLBJKB_02797 | | Pyruvate dehydrogenase [ubiquinone] | 1.00 | OHPLBJKB_04251 | | Protein HemY | low | > 73 |
| Escherichia coli ECRC101 | 1.00 | MCAODC_25060 | poxB | ubiquinone-dependent pyruvate dehydrogenase | 1.00 | MCAODC_04970 | hemY | protoheme IX biogenesis protein HemY | — | — |
| Escherichia coli ECRC99 | 1.00 | KEDOAH_22065 | poxB | ubiquinone-dependent pyruvate dehydrogenase | 1.00 | KEDOAH_13685 | hemY | protoheme IX biogenesis protein HemY | — | — |
| Escherichia coli ECRC102 | 1.00 | NIAGMN_03885 | poxB | ubiquinone-dependent pyruvate dehydrogenase | 1.00 | NIAGMN_12220 | hemY | protoheme IX biogenesis protein HemY | — | — |
| Escherichia coli ECRC98 | 1.00 | JDDGAC_09480 | poxB | ubiquinone-dependent pyruvate dehydrogenase | 1.00 | JDDGAC_18090 | hemY | protoheme IX biogenesis protein HemY | — | — |
| Escherichia coli ECOR38 | 0.99 | HEPCGN_02170 | poxB | ubiquinone-dependent pyruvate dehydrogenase | 1.00 | HEPCGN_13185 | hemY | protoheme IX biogenesis protein HemY | low | > 85 |
| Escherichia coli ECOR27 | 0.99 | NOLOHH_22240 | poxB | ubiquinone-dependent pyruvate dehydrogenase | 1.00 | NOLOHH_06610 | hemY | protoheme IX biogenesis protein HemY | low | > 57 |
| Escherichia coli ECRC101 | 0.99 | OKFHMN_05845 | poxB | ubiquinone-dependent pyruvate dehydrogenase | 1.00 | OKFHMN_14465 | hemY | protoheme IX biogenesis protein HemY | — | — |
| Escherichia fergusonii Becca | 0.99 | EFB2_03190 | | Pyruvate dehydrogenase [ubiquinone] | 1.00 | EFB2_04836 | | Protein HemY | low | > 86 |
| Escherichia coli ECRC62 | 0.99 | BNILDI_20495 | poxB | ubiquinone-dependent pyruvate dehydrogenase | 1.00 | BNILDI_04925 | hemY | protoheme IX biogenesis protein HemY | — | — |
| Escherichia coli Nissle 1917 | 0.99 | ECOLIN_RS04635 | | ubiquinone-dependent pyruvate dehydrogenase | 1.00 | ECOLIN_RS21820 | | protoheme IX biogenesis protein HemY | — | — |
| Enterobacter sp. TBS_079 | 0.94 | MPMX20_01532 | | Pyruvate dehydrogenase [ubiquinone] | 0.87 | MPMX20_04473 | | Protein HemY | low | > 85 |
| Enterobacter asburiae PDN3 | 0.94 | EX28DRAFT_2062 | | Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] | 0.88 | EX28DRAFT_4471 | | heme biosynthesis-associated TPR protein | low | > 76 |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | 0.93 | GFF4911 | | Pyruvate oxidase [ubiquinone, cytochrome] (EC 1.2.2.2) | 0.92 | GFF226 | | Uncharacterized protein EC-HemY, likely associated with heme metabolism based on gene clustering with hemC, hemD in Proteobacteria (unrelated to HemY-type PPO in GramPositives) | low | > 78 |
| Klebsiella michiganensis M5al | 0.92 | BWI76_RS09555 | | pyruvate oxidase | 0.89 | BWI76_RS01165 | | protoheme IX biogenesis protein HemY | low | > 92 |
| Rahnella sp. WP5 | 0.80 | EX31_RS18600 | | ubiquinone-dependent pyruvate dehydrogenase | 0.74 | EX31_RS15130 | | protoheme IX biogenesis protein HemY | low | > 89 |
| Pantoea sp. MT58 | 0.80 | IAI47_12970 | | ubiquinone-dependent pyruvate dehydrogenase | 0.73 | IAI47_18440 | | protoheme IX biogenesis protein HemY | low | > 76 |
| Serratia liquefaciens MT49 | 0.79 | IAI46_08465 | | ubiquinone-dependent pyruvate dehydrogenase | 0.72 | IAI46_00680 | | protoheme IX biogenesis protein HemY | low | > 86 |
| Pseudomonas fluorescens SBW25 | 0.66 | PFLU_RS12960 | | ubiquinone-dependent pyruvate dehydrogenase | 0.13 | PFLU_RS29195 | | heme biosynthesis protein HemY | low | > 109 |
| Pseudomonas fluorescens SBW25-INTG | 0.66 | PFLU_RS12960 | | ubiquinone-dependent pyruvate dehydrogenase | 0.13 | PFLU_RS29195 | | heme biosynthesis protein HemY | low | > 109 |
| Pseudomonas simiae WCS417 | 0.66 | PS417_12270 | | pyruvate dehydrogenase | 0.13 | PS417_27515 | | heme biosynthesis protein HemY | low | > 88 |
| Pseudomonas syringae pv. syringae B728a | 0.65 | Psyr_2314 | | pyruvate dehydrogenase (cytochrome) | 0.11 | Psyr_0059 | | HemY, N-terminal:HemY, N-terminal:HemY, N-terminal | low | > 86 |
| Pseudomonas syringae pv. syringae B728a ΔmexB | 0.65 | Psyr_2314 | | pyruvate dehydrogenase (cytochrome) | 0.11 | Psyr_0059 | | HemY, N-terminal:HemY, N-terminal:HemY, N-terminal | low | > 86 |
| Pseudomonas sp. RS175 | 0.26 | PFR28_01756 | | Putative thiamine pyrophosphate-containing protein YdaP | 0.13 | PFR28_04363 | | Protein HemY | low | > 88 |
Not shown: 16 genomes with orthologs for b0871 only; 19 genomes with orthologs for b3802 only