Conservation of cofitness between Rv0266c and Rv2406c in Mycobacterium tuberculosis H37Rv

14 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Mycobacterium tuberculosis H37Rv 1.0 Rv0266c Probable 5-oxoprolinase OplA (5-oxo-L-prolinase) (pyroglutamase) (5-OPASE) 1.0 Rv2406c Conserved protein 0.25 16
Paraburkholderia sabiae LMG 24235 0.61 QEN71_RS11485 hydantoinase B/oxoprolinase family protein 0.35 QEN71_RS05205 CBS domain-containing protein low > 153
Cupriavidus basilensis FW507-4G11 0.61 RR42_RS09105 5-oxoprolinase 0.32 RR42_RS06470 hypothetical protein low > 128
Azospirillum brasilense Sp245 0.60 AZOBR_RS12245 5-oxoprolinase 0.42 AZOBR_RS20240 histidine kinase — —
Azospirillum sp. SherDot2 0.58 MPMX19_01662 hypothetical protein 0.41 MPMX19_04897 hypothetical protein — —
Hydrogenophaga sp. GW460-11-11-14-LB1 0.58 GFF5350 5-oxoprolinase (EC 3.5.2.9) 0.31 GFF5244 Inosine-5'-monophosphate dehydrogenase (EC 1.1.1.205) low > 90
Acidovorax sp. GW101-3H11 0.58 Ac3H11_153 Similar to 5-oxoprolinase (EC 3.5.2.9) and Methylhydantoinases A, B (EC 3.5.2.14), contradiction in experimental data (see Annotation) 0.30 Ac3H11_3223 Inosine-5'-monophosphate dehydrogenase (EC 1.1.1.205) low > 79
Xanthobacter sp. DMC5 0.58 GFF4369 hypothetical protein 0.47 GFF1950 Inosine-5'-monophosphate dehydrogenase — —
Variovorax sp. OAS795 0.57 ABID97_RS11690 hydantoinase B/oxoprolinase family protein 0.31 ABID97_RS20940 CBS domain-containing protein low > 91
Caulobacter crescentus NA1000 Δfur 0.56 CCNA_02454 N-methylhydantoinase HyuB 0.41 CCNA_02709 CBS domain containing protein low > 67
Caulobacter crescentus NA1000 0.56 CCNA_02454 N-methylhydantoinase HyuB 0.41 CCNA_02709 CBS domain containing protein low > 66
Sinorhizobium meliloti 1021 0.55 SM_b20023 hypothetical protein 0.38 SMc01002 hypothetical protein low > 103
Bosea sp. OAE506 0.54 ABIE41_RS11590 hydantoinase B/oxoprolinase family protein 0.45 ABIE41_RS14035 CBS domain-containing protein — —
Rhizobium sp. OAE497 0.54 ABIE40_RS20570 hydantoinase B/oxoprolinase family protein 0.41 ABIE40_RS09735 CBS domain-containing protein — —
Sphingobium sp. HT1-2 0.51 GFF4783 5-oxoprolinase (EC 3.5.2.9), HyuA-like domain / 5-oxoprolinase (EC 3.5.2.9), HyuB-like domain 0.34 GFF4097 CBS domain protein low > 95

Not shown: 2 genomes with orthologs for Rv0266c only; 53 genomes with orthologs for Rv2406c only