Conservation of cofitness between HER17_RS21350 and HER17_RS17045 in Pectobacterium carotovorum WPP14

27 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Pectobacterium carotovorum WPP14 1.0 HER17_RS21350 EAL domain-containing protein 1.0 HER17_RS17045 Zn-dependent oxidoreductase 0.55 16
Pantoea sp. MT58 0.45 IAI47_01435 EAL domain-containing protein 0.63 IAI47_06830 Zn-dependent oxidoreductase low > 76
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.31 GFF4237 diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s) 0.80 GFF2490 Starvation sensing protein RspB low > 78
Escherichia coli ECRC102 0.30 NIAGMN_23805 eAL EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant) 0.25 NIAGMN_09210 lgoD L-galactonate oxidoreductase — —
Escherichia coli ECRC99 0.30 KEDOAH_23215 eAL EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant) 0.25 KEDOAH_16785 lgoD L-galactonate oxidoreductase — —
Escherichia coli ECRC98 0.30 JDDGAC_08140 eAL EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant) 0.25 JDDGAC_14955 lgoD L-galactonate oxidoreductase low > 86
Escherichia coli ECRC101 0.30 MCAODC_23905 eAL EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant) 0.25 MCAODC_01875 lgoD L-galactonate oxidoreductase low > 87
Escherichia coli ECRC100 0.30 OKFHMN_04530 eAL EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant) 0.25 OKFHMN_11360 lgoD L-galactonate oxidoreductase — —
Enterobacter sp. TBS_079 0.21 MPMX20_02720 putative cyclic di-GMP phosphodiesterase PdeD 0.81 MPMX20_02093 Starvation-sensing protein RspB low > 85
Pseudomonas fluorescens SBW25-INTG 0.21 PFLU_RS14595 EAL domain-containing protein 0.20 PFLU_RS19505 erythritol/L-threitol dehydrogenase low > 109
Pseudomonas fluorescens SBW25 0.21 PFLU_RS14595 EAL domain-containing protein 0.20 PFLU_RS19505 erythritol/L-threitol dehydrogenase low > 109
Pseudomonas fluorescens FW300-N2C3 0.21 AO356_22830 diguanylate phosphodiesterase 0.43 AO356_28545 alcohol dehydrogenase — —
Klebsiella michiganensis M5al 0.21 BWI76_RS17880 c-di-GMP phosphodiesterase 0.80 BWI76_RS15890 Zn-dependent oxidoreductase low > 92
Pseudomonas simiae WCS417 0.20 PS417_14020 diguanylate phosphodiesterase 0.20 PS417_17720 xylitol 2-dehydrogenase (EC 1.1.1.9) (from data) low > 88
Enterobacter asburiae PDN3 0.20 EX28DRAFT_1790 FOG: EAL domain 0.81 EX28DRAFT_1456 Threonine dehydrogenase and related Zn-dependent dehydrogenases low > 76
Serratia liquefaciens MT49 0.20 IAI46_14800 EAL domain-containing protein 0.71 IAI46_19030 Zn-dependent oxidoreductase low > 86
Escherichia fergusonii Becca 0.20 EFB2_01680 putative cyclic di-GMP phosphodiesterase PdeN 0.76 EFB2_02412 Starvation-sensing protein RspB low > 86
Escherichia coli BW25113 0.20 b2176 rtn hypothetical protein (NCBI) 0.76 b1580 rspB predicted oxidoreductase, Zn-dependent and NAD(P)-binding (NCBI) low > 76
Escherichia coli HS(pFamp)R (ATCC 700891) 0.20 OHPLBJKB_01533 putative cyclic di-GMP phosphodiesterase PdeN 0.63 OHPLBJKB_02146 Starvation-sensing protein RspB low > 73
Escherichia coli ECOR27 0.20 NOLOHH_14970 pdeN cyclic di-GMP phosphodiesterase 0.76 NOLOHH_18315 rspB Zn-dependent oxidoreductase low > 75
Escherichia coli ECOR38 0.20 HEPCGN_22660 pdeN cyclic di-GMP phosphodiesterase 0.76 HEPCGN_06190 rspB Zn-dependent oxidoreductase low > 87
Escherichia coli Nissle 1917 0.20 ECOLIN_RS12725 cyclic di-GMP phosphodiesterase 0.76 ECOLIN_RS08835 Zn-dependent oxidoreductase — —
Escherichia coli ECRC62 0.20 BNILDI_13890 pdeN cyclic di-GMP phosphodiesterase 0.76 BNILDI_17105 rspB Zn-dependent oxidoreductase low > 75
Escherichia coli BL21 0.20 ECD_02106 resistance protein for phages lambda and N4, putative membrane-anchored cyclic-di-GMP phosphodiesterase 0.76 ECD_01549 putative Zn-dependent NAD(P)-binding oxidoreductase — —
Dickeya dadantii 3937 0.18 DDA3937_RS13005 EAL domain-containing protein 0.81 DDA3937_RS14970 Zn-dependent oxidoreductase low > 74
Dickeya dianthicola ME23 0.18 DZA65_RS13535 EAL domain-containing protein 0.81 DZA65_RS15815 Zn-dependent oxidoreductase low > 75
Dickeya dianthicola 67-19 0.17 HGI48_RS13070 EAL domain-containing protein 0.80 HGI48_RS15070 Zn-dependent oxidoreductase low > 71
Paraburkholderia sabiae LMG 24235 0.16 QEN71_RS37740 EAL domain-containing protein 0.21 QEN71_RS11430 zinc-binding alcohol dehydrogenase family protein low > 153

Not shown: 9 genomes with orthologs for HER17_RS21350 only; 23 genomes with orthologs for HER17_RS17045 only