Conservation of cofitness between HER17_RS14245 and HER17_RS13490 in Pectobacterium carotovorum WPP14

25 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Pectobacterium carotovorum WPP14 1.0 HER17_RS14245 response regulator transcription factor 1.0 HER17_RS13490 NAD-dependent malic enzyme 0.53 13
Klebsiella michiganensis M5al 0.71 BWI76_RS06060 DNA-binding response regulator 0.77 BWI76_RS13830 NAD-dependent malic enzyme low > 92
Escherichia coli ECRC98 0.69 JDDGAC_12360 citB DNA-binding response regulator 0.77 JDDGAC_03850 maeA malate dehydrogenase low > 86
Escherichia coli ECRC99 0.69 KEDOAH_19265 citB DNA-binding response regulator 0.77 KEDOAH_27080 maeA malate dehydrogenase — —
Escherichia coli ECRC101 0.69 MCAODC_27935 citB DNA-binding response regulator 0.77 MCAODC_16580 maeA malate dehydrogenase low > 87
Escherichia coli ECRC100 0.69 OKFHMN_08705 citB DNA-binding response regulator 0.77 OKFHMN_01360 maeA malate dehydrogenase low > 80
Escherichia coli ECRC102 0.69 NIAGMN_06760 citB DNA-binding response regulator 0.77 NIAGMN_25490 maeA malate dehydrogenase — —
Vibrio cholerae E7946 ATCC 55056 0.60 CSW01_17605 DNA-binding response regulator 0.71 CSW01_06015 NAD-dependent malic enzyme low > 62
Enterobacter asburiae PDN3 0.42 EX28DRAFT_3952 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain 0.77 EX28DRAFT_1103 Malic enzyme low > 76
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.42 GFF304 Transcriptional regulatory protein UhpA 0.77 GFF2556 NAD-dependent malic enzyme (EC 1.1.1.38) low > 78
Escherichia fergusonii Becca 0.41 EFB2_00029 Transcriptional regulatory protein UhpA 0.77 EFB2_02512 NAD-dependent malic enzyme low > 86
Escherichia coli BW25113 0.41 b3669 uhpA DNA-binding response regulator in two-component regulatory system wtih UhpB (NCBI) 0.77 b1479 sfcA NAD-linked malate dehydrogenase (malic enzyme) (VIMSS) low > 76
Escherichia coli ECOR27 0.41 NOLOHH_07335 uhpA_G97D DNA-binding response regulator UhpA 0.77 NOLOHH_19035 maeA malate dehydrogenase low > 75
Escherichia coli BL21 0.41 ECD_03553 response regulator in two-component regulatory system wtih UhpB 0.77 ECD_01437 malate dehydrogenase, decarboxylating, NAD-requiring; malic enzyme — —
Escherichia coli ECOR38 0.41 HEPCGN_13905 uhpA_G97D DNA-binding response regulator UhpA 0.77 HEPCGN_26435 maeA malate dehydrogenase low > 87
Escherichia coli Nissle 1917 0.41 ECOLIN_RS21160 transcriptional regulator UhpA 0.77 ECOLIN_RS08525 malate dehydrogenase — —
Escherichia coli ECRC62 0.41 BNILDI_04190 uhpA_G97D DNA-binding response regulator UhpA 0.77 BNILDI_17520 maeA malate dehydrogenase low > 75
Dickeya dianthicola 67-19 0.41 HGI48_RS02840 transcriptional regulator UhpA 0.89 HGI48_RS08645 NAD-dependent malic enzyme low > 71
Enterobacter sp. TBS_079 0.41 MPMX20_00033 Transcriptional regulatory protein UhpA 0.77 MPMX20_02369 NAD-dependent malic enzyme low > 85
Escherichia coli HS(pFamp)R (ATCC 700891) 0.41 OHPLBJKB_00031 Transcriptional regulatory protein UhpA 0.77 OHPLBJKB_02238 NAD-dependent malic enzyme low > 73
Dickeya dadantii 3937 0.41 DDA3937_RS02865 transcriptional regulator UhpA 0.89 DDA3937_RS08480 NAD-dependent malic enzyme low > 74
Dickeya dianthicola ME23 0.41 DZA65_RS03015 transcriptional regulator UhpA 0.89 DZA65_RS08935 NAD-dependent malic enzyme low > 75
Serratia liquefaciens MT49 0.40 IAI46_00435 transcriptional regulator UhpA 0.88 IAI46_07935 NAD-dependent malic enzyme low > 86
Paraburkholderia bryophila 376MFSha3.1 0.33 H281DRAFT_01334 two component transcriptional regulator, LuxR family 0.34 H281DRAFT_00026 malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+) — —
Alteromonas macleodii MIT1002 0.30 MIT1002_03526 Nitrogen regulation protein C 0.64 MIT1002_00455 NAD-dependent malic enzyme low > 70
Mycobacterium tuberculosis H37Rv 0.26 Rv3133c Two component transcriptional regulatory protein DevR (probably LuxR/UhpA-family) 0.37 Rv2332 Probable [NAD] dependent malate oxidoreductase Mez (malic enzyme) (NAD-malic enzyme) (malate dehydrogenase (oxaloacetate decarboxylating)) (pyruvic-malic carboxylase) (NAD-me) low > 58

Not shown: 14 genomes with orthologs for HER17_RS14245 only; 12 genomes with orthologs for HER17_RS13490 only