Conservation of cofitness between GFF458 and GFF747 in Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

22 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 1.0 GFF458 2-ketoaldonate reductase, broad specificity (EC 1.1.1.215) (EC 1.1.1.-) 1.0 GFF747 Multidrug translocase MdfA 0.40 10
Escherichia coli BW25113 0.85 b3553 yiaE putative dehydrogenase (VIMSS) 0.92 b0842 cmr multidrug efflux system protein (NCBI) low > 76
Escherichia coli ECRC98 0.84 JDDGAC_19650 ghrB glyoxylate/hydroxypyruvate reductase GhrB 0.92 JDDGAC_09660 mdfA multidrug efflux MFS transporter MdfA — —
Escherichia fergusonii Becca 0.84 EFB2_00254 Glyoxylate/hydroxypyruvate reductase B 0.92 EFB2_03264 Multidrug transporter MdfA low > 86
Escherichia coli ECRC101 0.84 OKFHMN_16020 ghrB glyoxylate/hydroxypyruvate reductase GhrB 0.92 OKFHMN_06025 mdfA multidrug efflux MFS transporter MdfA — —
Escherichia coli BL21 0.84 ECD_03403 glyoxylate/hydroxypyruvate reductase B 0.92 ECD_00809 multidrug efflux system protein low > 60
Escherichia coli ECOR27 0.84 NOLOHH_07965 ghrB glyoxylate/hydroxypyruvate reductase GhrB 0.92 NOLOHH_22395 mdfA multidrug efflux MFS transporter MdfA low > 57
Escherichia coli ECRC101 0.84 MCAODC_06535 ghrB glyoxylate/hydroxypyruvate reductase GhrB 0.92 MCAODC_25240 mdfA multidrug efflux MFS transporter MdfA — —
Escherichia coli ECRC62 0.84 BNILDI_03580 ghrB glyoxylate/hydroxypyruvate reductase GhrB 0.92 BNILDI_20655 mdfA multidrug efflux MFS transporter MdfA — —
Escherichia coli ECRC102 0.84 NIAGMN_13780 ghrB glyoxylate/hydroxypyruvate reductase GhrB 0.92 NIAGMN_04070 mdfA multidrug efflux MFS transporter MdfA — —
Escherichia coli ECOR38 0.84 HEPCGN_14910 ghrB glyoxylate/hydroxypyruvate reductase GhrB 0.92 HEPCGN_02005 mdfA multidrug efflux MFS transporter MdfA low > 85
Escherichia coli Nissle 1917 0.84 ECOLIN_RS20330 glyoxylate/hydroxypyruvate reductase GhrB 0.92 ECOLIN_RS04475 multidrug efflux MFS transporter MdfA low > 52
Escherichia coli HS(pFamp)R (ATCC 700891) 0.84 OHPLBJKB_00153 Glyoxylate/hydroxypyruvate reductase B 0.92 OHPLBJKB_02868 Multidrug transporter MdfA low > 73
Klebsiella michiganensis M5al 0.84 BWI76_RS26960 bifunctional glyoxylate/hydroxypyruvate reductase B 0.85 BWI76_RS09160 multidrug transporter MdfA low > 92
Enterobacter sp. TBS_079 0.80 MPMX20_00177 Glyoxylate/hydroxypyruvate reductase B 0.88 MPMX20_01481 Multidrug transporter MdfA low > 85
Enterobacter asburiae PDN3 0.77 EX28DRAFT_3817 Lactate dehydrogenase and related dehydrogenases 0.86 EX28DRAFT_2123 Major Facilitator Superfamily low > 76
Serratia liquefaciens MT49 0.70 IAI46_00085 glyoxylate/hydroxypyruvate reductase GhrB 0.71 IAI46_00250 MFS transporter low > 86
Rahnella sp. WP5 0.67 EX31_RS05925 glyoxylate/hydroxypyruvate reductase GhrB 0.73 EX31_RS05745 MFS transporter low > 89
Pantoea sp. MT58 0.66 IAI47_00110 glyoxylate/hydroxypyruvate reductase GhrB 0.53 IAI47_19975 MFS transporter low > 76
Pseudomonas sp. RS175 0.56 PFR28_01596 Glyoxylate/hydroxypyruvate reductase B 0.25 PFR28_01655 Multidrug transporter MdfA low > 88
Pseudomonas fluorescens FW300-N1B4 0.54 Pf1N1B4_4763 2-ketogluconate 6-phosphate reductase (EC 1.1.1.43) 0.29 Pf1N1B4_4699 Multidrug translocase MdfA low > 87
Pseudomonas putida KT2440 0.48 PP_3376 putative phosphonate dehydrogenase 0.34 PP_1354 putative multidrug efflux MFS transporter low > 96
Acinetobacter radioresistens SK82 0.41 MPMX26_01125 Glyoxylate/hydroxypyruvate reductase B 0.34 MPMX26_02770 Chloramphenicol resistance protein CraA low > 36

Not shown: 60 genomes with orthologs for GFF458 only; 1 genomes with orthologs for GFF747 only