Conservation of cofitness between GFF409 and GFF669 in Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

22 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 1.0 GFF409 L-lactate dehydrogenase (EC 1.1.2.3) 1.0 GFF669 UPF0098 protein ybhB 0.47 4
Escherichia coli BW25113 0.95 b3605 lldD L-lactate dehydrogenase, FMN-linked (NCBI) 0.95 b0773 ybhB predicted kinase inhibitor (NCBI) low > 76
Escherichia coli BL21 0.95 ECD_03463 L-lactate dehydrogenase, FMN-linked 0.95 ECD_00740 kinase inhibitor-like protein, UPF0098 family low > 60
Escherichia coli HS(pFamp)R (ATCC 700891) 0.95 OHPLBJKB_00094 L-lactate dehydrogenase 0.95 OHPLBJKB_02940 hypothetical protein low > 73
Escherichia coli ECRC98 0.95 JDDGAC_19395 lldD quinone-dependent L-lactate dehydrogenase 0.95 JDDGAC_10045 ybhB kinase inhibitor — —
Escherichia coli ECRC101 0.95 OKFHMN_15770 lldD quinone-dependent L-lactate dehydrogenase 0.95 OKFHMN_06410 ybhB kinase inhibitor — —
Escherichia coli ECRC99 0.95 KEDOAH_12380 lldD quinone-dependent L-lactate dehydrogenase 0.95 KEDOAH_21500 ybhB kinase inhibitor — —
Escherichia coli ECOR27 0.95 NOLOHH_07650 lldD quinone-dependent L-lactate dehydrogenase 0.95 NOLOHH_22780 ybhB kinase inhibitor low > 57
Escherichia coli ECRC101 0.95 MCAODC_06280 lldD quinone-dependent L-lactate dehydrogenase 0.95 MCAODC_25625 ybhB kinase inhibitor — —
Escherichia coli ECRC62 0.95 BNILDI_03865 lldD quinone-dependent L-lactate dehydrogenase 0.95 BNILDI_21050 ybhB kinase inhibitor — —
Escherichia coli ECRC102 0.95 NIAGMN_13530 lldD quinone-dependent L-lactate dehydrogenase 0.95 NIAGMN_04455 ybhB kinase inhibitor — —
Escherichia coli ECOR38 0.95 HEPCGN_14610 lldD quinone-dependent L-lactate dehydrogenase 0.94 HEPCGN_01630 ybhB kinase inhibitor low > 85
Escherichia coli Nissle 1917 0.95 ECOLIN_RS20580 quinone-dependent L-lactate dehydrogenase 0.95 ECOLIN_RS04115 kinase inhibitor low > 52
Enterobacter asburiae PDN3 0.94 EX28DRAFT_3855 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases 0.89 EX28DRAFT_2218 Raf kinase inhibitor-like protein, YbhB/YbcL family low > 76
Enterobacter sp. TBS_079 0.94 MPMX20_00129 L-lactate dehydrogenase 0.89 MPMX20_01401 hypothetical protein low > 85
Escherichia fergusonii Becca 0.93 EFB2_00205 L-lactate dehydrogenase 0.95 EFB2_03333 hypothetical protein low > 86
Pantoea sp. MT58 0.89 IAI47_15020 FMN-dependent L-lactate dehydrogenase LldD 0.80 IAI47_13540 kinase inhibitor low > 76
Rahnella sp. WP5 0.83 EX31_RS00640 FMN-dependent L-lactate dehydrogenase LldD 0.73 EX31_RS23655 kinase inhibitor low > 89
Serratia liquefaciens MT49 0.82 IAI46_20620 FMN-dependent L-lactate dehydrogenase LldD 0.76 IAI46_06510 kinase inhibitor low > 86
Castellaniella sp019104865 MT123 0.80 ABCV34_RS10285 FMN-dependent L-lactate dehydrogenase LldD 0.24 ABCV34_RS10560 YbhB/YbcL family Raf kinase inhibitor-like protein low > 48
Brevundimonas sp. GW460-12-10-14-LB2 0.78 A4249_RS07680 FMN-dependent L-lactate dehydrogenase LldD 0.52 A4249_RS00880 YbhB/YbcL family Raf kinase inhibitor-like protein low > 48
Ralstonia solanacearum PSI07 0.43 RPSI07_RS14000 alpha-hydroxy-acid oxidizing protein 0.23 RPSI07_RS21570 YbhB/YbcL family Raf kinase inhibitor-like protein low > 81
Mycobacterium tuberculosis H37Rv 0.28 Rv1872c Possible L-lactate dehydrogenase (cytochrome) LldD2 0.41 Rv2140c Conserved protein TB18.6 low > 58

Not shown: 35 genomes with orthologs for GFF409 only; 5 genomes with orthologs for GFF669 only