Conservation of cofitness between GFF3147 and GFF2188 in Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

22 genomes with putative orthologs of both genes

Organism	Ratio1	Gene1	Name1	Description1	Ratio2	Gene2	Name2	Description2	Cofit	Rank
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868	1.0	GFF3147		FIG074102: hypothetical protein	1.0	GFF2188		RND efflux system, inner membrane transporter CmeB	0.64	6
Escherichia coli ECOR38	0.97	HEPCGN_17690	yqiB	DUF1249 domain-containing protein	0.95	HEPCGN_21140	acrD	multidrug efflux RND transporter permease AcrD	low	> 87
Escherichia coli HS(pFamp)R (ATCC 700891)	0.97	OHPLBJKB_00670		hypothetical protein	0.95	OHPLBJKB_01261		Multidrug efflux pump subunit AcrB	low	> 73
Escherichia coli ECRC62	0.97	BNILDI_00895	yqiB	DUF1249 domain-containing protein	0.95	BNILDI_12460	acrD	multidrug efflux RND transporter permease AcrD	low	> 75
Escherichia coli ECRC102	0.97	NIAGMN_16580	yqiB	DUF1249 domain-containing protein	0.95	NIAGMN_19740	acrD	multidrug efflux RND transporter permease AcrD	—	—
Escherichia coli ECRC99	0.97	KEDOAH_09330	yqiB	DUF1249 domain-containing protein	0.95	KEDOAH_06250	acrD	multidrug efflux RND transporter permease AcrD	—	—
Escherichia coli ECRC100	0.97	OKFHMN_18815	yqiB	DUF1249 domain-containing protein	0.95	OKFHMN_21970	acrD	multidrug efflux RND transporter permease AcrD	low	> 80
Escherichia coli Nissle 1917	0.97	ECOLIN_RS17505		DUF1249 family protein	0.95	ECOLIN_RS14090		multidrug efflux RND transporter permease AcrD	low	> 55
Escherichia coli ECRC101	0.97	MCAODC_09330	yqiB	DUF1249 domain-containing protein	0.95	MCAODC_12500	acrD	multidrug efflux RND transporter permease AcrD	low	> 87
Escherichia coli BW25113	0.97	b3033	yqiB	predicted dehydrogenase (NCBI)	0.95	b2470	acrD	aminoglycoside/multidrug efflux system (NCBI)	low	> 76
Escherichia coli ECOR27	0.97	NOLOHH_10620	yqiB	DUF1249 domain-containing protein	0.95	NOLOHH_13650	acrD	multidrug efflux RND transporter permease AcrD	low	> 75
Escherichia coli BL21	0.97	ECD_02905		DUF1249 protein YqiB	0.95	ECD_02361		aminoglycoside/multidrug efflux system	low	> 61
Escherichia fergusonii Becca	0.97	EFB2_00775		hypothetical protein	0.95	EFB2_01418		Multidrug efflux pump subunit AcrB	low	> 86
Escherichia coli ECRC98	0.96	JDDGAC_22450	yqiB	DUF1249 domain-containing protein	0.95	JDDGAC_25915	acrD	multidrug efflux RND transporter permease AcrD	low	> 86
Enterobacter asburiae PDN3	0.95	EX28DRAFT_3071		Uncharacterized protein conserved in bacteria	0.92	EX28DRAFT_0191		The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family	low	> 76
Enterobacter sp. TBS_079	0.94	MPMX20_03880		hypothetical protein	0.92	MPMX20_03331		Multidrug efflux pump subunit AcrB	low	> 85
Klebsiella michiganensis M5al	0.93	BWI76_RS24390		hypothetical protein	0.93	BWI76_RS20860		aminoglycoside/multidrug transporter subunit AcrD	low	> 92
Serratia liquefaciens MT49	0.89	IAI46_21935		DUF1249 family protein	0.84	IAI46_18690		multidrug efflux RND transporter permease AcrD	low	> 86
Rahnella sp. WP5	0.88	EX31_RS25980		DUF1249 family protein	0.80	EX31_RS22805		multidrug efflux RND transporter permease AcrD	low	> 89
Pantoea sp. MT58	0.85	IAI47_03145		DUF1249 family protein	0.83	IAI47_05310		multidrug efflux RND transporter permease AcrD	low	> 76
Pectobacterium carotovorum WPP14	0.81	HER17_RS19815		DUF1249 family protein	0.81	HER17_RS01560		multidrug efflux RND transporter permease AcrD	0.56	54
Pseudomonas fluorescens SBW25-INTG	0.30	PFLU_RS02450		DUF1249 domain-containing protein	0.58	PFLU_RS20135		multidrug efflux RND transporter permease subunit	low	> 109
Pseudomonas fluorescens SBW25	0.30	PFLU_RS02450		DUF1249 domain-containing protein	0.58	PFLU_RS20135		multidrug efflux RND transporter permease subunit	low	> 109

Not shown: 23 genomes with orthologs for GFF3147 only; 4 genomes with orthologs for GFF2188 only