Conservation of cofitness between BWI76_RS22090 and BWI76_RS19025 in Klebsiella michiganensis M5al

25 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Klebsiella michiganensis M5al 1.0 BWI76_RS22090 transcriptional regulator 1.0 BWI76_RS19025 phosphogluconate dehydrogenase (NADP(+)-dependent, decarboxylating) 0.36 13
Enterobacter sp. TBS_079 0.96 MPMX20_03562 Transcriptional repressor MprA 0.94 MPMX20_03014 6-phosphogluconate dehydrogenase, decarboxylating low > 85
Enterobacter asburiae PDN3 0.96 EX28DRAFT_2767 Transcriptional regulators 0.95 EX28DRAFT_0529 6-phosphogluconate dehydrogenase (decarboxylating) — —
Escherichia coli Nissle 1917 0.95 ECOLIN_RS14960 multidrug efflux transporter EmrAB transcriptional repressor EmrR 0.95 ECOLIN_RS11990 NADP-dependent phosphogluconate dehydrogenase low > 55
Escherichia coli HS(pFamp)R (ATCC 700891) 0.95 OHPLBJKB_01049 Transcriptional repressor MprA 0.98 OHPLBJKB_01659 6-phosphogluconate dehydrogenase, decarboxylating 0.64 3
Escherichia coli ECRC98 0.95 JDDGAC_24450 emrR multidrug efflux transporter EmrAB transcriptional repressor EmrR 0.95 JDDGAC_28580 gndA NADP-dependent phosphogluconate dehydrogenase low > 86
Escherichia coli ECOR27 0.95 NOLOHH_12625 emrR multidrug efflux transporter EmrAB transcriptional repressor EmrR 0.95 NOLOHH_15785 gndA NADP-dependent phosphogluconate dehydrogenase low > 75
Escherichia fergusonii Becca 0.95 EFB2_01244 Transcriptional repressor MprA 0.95 EFB2_01826 6-phosphogluconate dehydrogenase, decarboxylating low > 86
Escherichia coli BW25113 0.95 b2684 mprA DNA-binding transcriptional repressor of microcin B17 synthesis and multidrug efflux (NCBI) 0.95 b2029 gnd 6-phosphogluconate dehydrogenase (NCBI) low > 76
Escherichia coli ECRC100 0.95 OKFHMN_20785 emrR multidrug efflux transporter EmrAB transcriptional repressor EmrR 0.95 OKFHMN_24470 gndA NADP-dependent phosphogluconate dehydrogenase low > 80
Escherichia coli ECRC102 0.95 NIAGMN_18555 emrR multidrug efflux transporter EmrAB transcriptional repressor EmrR 0.95 NIAGMN_22415 gndA NADP-dependent phosphogluconate dehydrogenase — —
Escherichia coli ECRC99 0.95 KEDOAH_07350 emrR multidrug efflux transporter EmrAB transcriptional repressor EmrR 0.95 KEDOAH_03680 gndA NADP-dependent phosphogluconate dehydrogenase — —
Escherichia coli ECOR38 0.95 HEPCGN_19985 emrR multidrug efflux transporter EmrAB transcriptional repressor EmrR 0.94 HEPCGN_03175 gndA NADP-dependent phosphogluconate dehydrogenase low > 87
Escherichia coli BL21 0.95 ECD_02539 transcriptional repressor of microcin B17 synthesis and multidrug efflux 0.94 ECD_01931 6-phosphogluconate dehydrogenase, decarboxylating low > 61
Escherichia coli ECRC101 0.94 MCAODC_11310 emrR multidrug efflux transporter EmrAB transcriptional repressor EmrR 0.95 MCAODC_20470 gndA NADP-dependent phosphogluconate dehydrogenase low > 87
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.94 GFF1591 Transcription repressor of tripartite multidrug resistance system 0.95 GFF3903 6-phosphogluconate dehydrogenase, decarboxylating (EC 1.1.1.44) low > 78
Escherichia coli ECRC62 0.94 BNILDI_11185 emrR multidrug efflux transporter EmrAB transcriptional repressor EmrR 0.95 BNILDI_14695 gndA NADP-dependent phosphogluconate dehydrogenase low > 75
Pantoea sp. MT58 0.81 IAI47_04505 transcriptional repressor MprA 0.89 IAI47_07035 NADP-dependent phosphogluconate dehydrogenase — —
Erwinia tracheiphila SCR3 0.80 LU632_RS16835 mprA transcriptional repressor MprA 0.86 LU632_RS08890 gndA NADP-dependent phosphogluconate dehydrogenase 0.55 7
Serratia liquefaciens MT49 0.78 IAI46_19990 transcriptional repressor MprA 0.89 IAI46_08160 NADP-dependent phosphogluconate dehydrogenase — —
Rahnella sp. WP5 0.76 EX31_RS13645 transcriptional repressor MprA 0.88 EX31_RS11475 NADP-dependent phosphogluconate dehydrogenase — —
Dickeya dianthicola 67-19 0.71 HGI48_RS16825 transcriptional repressor MprA 0.88 HGI48_RS06840 NADP-dependent phosphogluconate dehydrogenase low > 71
Dickeya dadantii 3937 0.70 DDA3937_RS16755 transcriptional repressor MprA 0.89 DDA3937_RS06805 NADP-dependent phosphogluconate dehydrogenase low > 74
Dickeya dianthicola ME23 0.70 DZA65_RS17900 transcriptional repressor MprA 0.89 DZA65_RS07180 NADP-dependent phosphogluconate dehydrogenase low > 75
Pectobacterium carotovorum WPP14 0.69 HER17_RS04470 transcriptional repressor MprA 0.89 HER17_RS14505 NADP-dependent phosphogluconate dehydrogenase low > 75
Dyella japonica UNC79MFTsu3.2 0.29 ABZR86_RS13425 MarR family transcriptional regulator 0.74 ABZR86_RS13330 NADP-dependent phosphogluconate dehydrogenase low > 74

Not shown: 4 genomes with orthologs for BWI76_RS22090 only; 28 genomes with orthologs for BWI76_RS19025 only