Conservation of cofitness between b0334 and b2026 in Escherichia coli BW25113

19 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BW25113 1.0 b0334 prpD 2-methylcitrate dehydratase (NCBI) 1.0 b2026 hisI bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein (NCBI) 0.36 19
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_03337 2-methylcitrate dehydratase 0.96 OHPLBJKB_01674 Histidine biosynthesis bifunctional protein HisIE low > 73
Escherichia coli ECOR27 1.00 NOLOHH_01765 bifunctional 2-methylcitrate dehydratase/aconitate hydratase 0.92 NOLOHH_15800 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE low > 57
Escherichia coli BL21 1.00 ECD_00288 2-methylcitrate dehydratase 1.00 ECD_01928 phosphoribosyl-AMP cyclohydrolase and phosphoribosyl-ATP pyrophosphatase low > 60
Escherichia fergusonii Becca 1.00 EFB2_03704 2-methylcitrate dehydratase 0.98 EFB2_01830 Histidine biosynthesis bifunctional protein HisIE low > 86
Escherichia coli ECRC62 1.00 BNILDI_23180 bifunctional 2-methylcitrate dehydratase/aconitate hydratase 0.98 BNILDI_14710 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE — —
Escherichia coli ECRC98 1.00 JDDGAC_12545 bifunctional 2-methylcitrate dehydratase/aconitate hydratase 0.99 JDDGAC_28595 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE — —
Escherichia coli ECRC102 1.00 NIAGMN_06945 bifunctional 2-methylcitrate dehydratase/aconitate hydratase 0.99 NIAGMN_22430 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE — —
Escherichia coli ECRC101 1.00 MCAODC_28120 bifunctional 2-methylcitrate dehydratase/aconitate hydratase 0.99 MCAODC_20455 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE — —
Escherichia coli ECRC99 1.00 KEDOAH_19075 bifunctional 2-methylcitrate dehydratase/aconitate hydratase 0.99 KEDOAH_03665 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE — —
Escherichia coli Nissle 1917 1.00 ECOLIN_RS02160 2-methylcitrate dehydratase 0.99 ECOLIN_RS11975 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE — —
Escherichia coli ECRC101 1.00 OKFHMN_08890 bifunctional 2-methylcitrate dehydratase/aconitate hydratase 0.99 OKFHMN_24485 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE — —
Escherichia coli ECOR38 0.99 HEPCGN_07475 bifunctional 2-methylcitrate dehydratase/aconitate hydratase 0.99 HEPCGN_03190 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE low > 85
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.95 GFF4265 2-methylcitrate dehydratase (EC 4.2.1.79) 0.89 GFF3906 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) / Phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) low > 78
Rhodanobacter denitrificans MT42 0.59 LRK55_RS00450 bifunctional 2-methylcitrate dehydratase/aconitate hydratase 0.56 LRK55_RS01355 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE low > 63
Rhodanobacter denitrificans FW104-10B01 0.59 LRK54_RS00675 bifunctional 2-methylcitrate dehydratase/aconitate hydratase 0.55 LRK54_RS01575 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE low > 59
Rhodanobacter sp. FW510-T8 0.59 OKGIIK_06580 prpD bifunctional 2-methylcitrate dehydratase/aconitate hydratase 0.55 OKGIIK_04980 hisIE bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE low > 52
Dyella japonica UNC79MFTsu3.2 0.58 ABZR86_RS08425 bifunctional 2-methylcitrate dehydratase/aconitate hydratase 0.54 ABZR86_RS06700 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE low > 74
Lysobacter sp. OAE881 0.56 ABIE51_RS06100 bifunctional 2-methylcitrate dehydratase/aconitate hydratase 0.47 ABIE51_RS13295 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE low > 62
Rahnella sp. WP5 0.46 EX31_RS11170 bifunctional 2-methylcitrate dehydratase/aconitate hydratase 0.76 EX31_RS11470 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE low > 89

Not shown: 20 genomes with orthologs for b0334 only; 30 genomes with orthologs for b2026 only