Orth | Species | Gene | Name | Description | Fitness | %Id | Cov |
| Escherichia coli BW25113 | b2481 | hyfA | hydrogenase 4 Fe-S subunit (VIMSS) | insig. | 100 | 100 |
o | Escherichia coli BL21 | ECD_02373 | | hydrogenase 4, 4Fe-4S subunit | insig. | 98 | 100 |
o | Escherichia coli ECRC101 | OKFHMN_21900 | hyfA | hydrogenase 4 subunit HyfA | sig. | 98 | 100 |
o | Escherichia coli ECRC101 | MCAODC_12430 | hyfA | hydrogenase 4 subunit HyfA | insig. | 98 | 100 |
o | Escherichia coli ECRC102 | NIAGMN_19670 | hyfA | hydrogenase 4 subunit HyfA | insig. | 98 | 100 |
o | Escherichia coli ECRC98 | JDDGAC_25845 | hyfA | hydrogenase 4 subunit HyfA | no data | 98 | 100 |
o | Escherichia coli ECRC99 | KEDOAH_06320 | hyfA | hydrogenase 4 subunit HyfA | no data | 98 | 100 |
o | Escherichia coli ECRC62 | BNILDI_12370 | hyfA | hydrogenase 4 subunit HyfA | insig. | 98 | 100 |
o | Escherichia coli ECOR27 | NOLOHH_13560 | hyfA | hydrogenase 4 subunit HyfA | cofit | 98 | 100 |
o | Escherichia coli HS(pFamp)R (ATCC 700891) | OHPLBJKB_01248 | | Hydrogenase-4 component A | insig. | 98 | 100 |
o | Escherichia coli ECOR38 | HEPCGN_21070 | hyfA | hydrogenase 4 subunit HyfA | cofit | 97 | 100 |
o | Dickeya dadantii 3937 | DDA3937_RS07475 | | 4Fe-4S dicluster domain-containing protein | insig. | 52 | 100 |
o | Dickeya dianthicola 67-19 | HGI48_RS07350 | | 4Fe-4S binding protein | insig. | 51 | 96 |
o | Dickeya dianthicola ME23 | DZA65_RS07860 | | 4Fe-4S dicluster domain-containing protein | insig. | 51 | 96 |
| Escherichia coli BL21 | ECD_02574 | | hydrogenase 3, Fe-S subunit | insig. | 51 | 90 |
| Serratia liquefaciens MT49 | IAI46_12535 | | 4Fe-4S dicluster domain-containing protein | no data | 48 | 100 |
| Rahnella sp. WP5 | EX31_RS19905 | | 4Fe-4S dicluster domain-containing protein | insig. | 51 | 91 |
| Escherichia fergusonii Becca | EFB2_01199 | | Hydrogenase-4 component A | insig. | 50 | 90 |
| Escherichia coli HS(pFamp)R (ATCC 700891) | OHPLBJKB_01010 | | Hydrogenase-4 component A | insig. | 50 | 90 |
| Escherichia coli Nissle 1917 | ECOLIN_RS15220 | | formate hydrogenlyase subunit HycB | insig. | 50 | 90 |
| Escherichia coli BW25113 | b2724 | hycB | hydrogenase 3, Fe-S subunit (NCBI) | sig. | 50 | 90 |
| Enterobacter asburiae PDN3 | EX28DRAFT_2815 | | Fe-S-cluster-containing hydrogenase components 2 | no data | 49 | 99 |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | GFF4717 | | Formate hydrogenlyase subunit 2 | insig. | 50 | 90 |
| Escherichia coli ECOR38 | HEPCGN_19765 | hycB | formate hydrogenlyase subunit HycB | cofit | 50 | 90 |
| Escherichia coli ECOR27 | NOLOHH_12420 | hycB | formate hydrogenlyase subunit HycB | cofit | 50 | 90 |
| Escherichia coli ECRC101 | OKFHMN_20575 | hycB | formate hydrogenlyase subunit HycB | insig. | 50 | 90 |
| Escherichia coli ECRC101 | MCAODC_11100 | hycB | formate hydrogenlyase subunit HycB | insig. | 50 | 90 |
| Escherichia coli ECRC102 | NIAGMN_18345 | hycB | formate hydrogenlyase subunit HycB | insig. | 50 | 90 |
| Escherichia coli ECRC62 | BNILDI_10970 | hycB | formate hydrogenlyase subunit HycB | insig. | 50 | 90 |
| Escherichia coli ECRC98 | JDDGAC_24240 | hycB | formate hydrogenlyase subunit HycB | no data | 50 | 90 |
| Escherichia coli ECRC99 | KEDOAH_07560 | hycB | formate hydrogenlyase subunit HycB | no data | 50 | 90 |
| Enterobacter sp. TBS_079 | MPMX20_03609 | | Hydrogenase-4 component A | insig. | 49 | 99 |
| Klebsiella michiganensis M5al | BWI76_RS22335 | | 4Fe-4S ferredoxin | insig. | 48 | 100 |
o | Azospirillum sp. SherDot2 | MPMX19_03516 | | Hydrogenase-4 component A | no data | 50 | 92 |
| Rahnella sp. WP5 | EX31_RS07260 | | formate-dependent uric acid utilization protein AegA | insig. | 40 | 99 |
| Pectobacterium carotovorum WPP14 | HER17_RS21750 | | 4Fe-4S dicluster domain-containing protein | no data | 39 | 91 |
| Rhodospirillum rubrum S1H | Rru_A0323 | | 4Fe-4S ferredoxin, iron-sulfur binding (NCBI) | insig. | 36 | 94 |
| Dickeya dadantii 3937 | DDA3937_RS07410 | | 4Fe-4S dicluster domain-containing protein | insig. | 40 | 91 |
| Dickeya dianthicola ME23 | DZA65_RS07795 | | 4Fe-4S dicluster domain-containing protein | insig. | 40 | 91 |
| Dickeya dianthicola 67-19 | HGI48_RS07285 | | 4Fe-4S dicluster domain-containing protein | insig. | 40 | 91 |
| Dickeya dadantii 3937 | DDA3937_RS21415 | | 4Fe-4S dicluster domain-containing protein | insig. | 37 | 94 |
| Pectobacterium carotovorum WPP14 | HER17_RS21755 | | formate-dependent uric acid utilization protein AegA | cofit | 39 | 91 |
| Dickeya dianthicola 67-19 | HGI48_RS21615 | | 4Fe-4S dicluster domain-containing protein | insig. | 38 | 94 |
| Dickeya dianthicola ME23 | DZA65_RS22600 | | 4Fe-4S dicluster domain-containing protein | cofit | 37 | 94 |
| Rahnella sp. WP5 | EX31_RS19945 | | electron transport protein HydN | insig. | 37 | 91 |
| Escherichia coli ECOR38 | HEPCGN_18905 | ygfS | Putative electron transport protein YgfS | cofit | 37 | 97 |
| Azospirillum sp. SherDot2 | MPMX19_03517 | | Hydrogenase-4 component A | no data | 37 | 86 |
| Dickeya dadantii 3937 | DDA3937_RS21410 | | formate-dependent uric acid utilization protein AegA | insig. | 36 | 97 |
| Klebsiella michiganensis M5al | BWI76_RS17545 | | oxidoreductase, 4Fe-4S subunit | no data | 34 | 93 |
| Escherichia coli ECOR38 | HEPCGN_21150 | aegA | formate-dependent uric acid utilization protein AegA | cofit | 38 | 89 |
| Escherichia coli ECOR27 | NOLOHH_11545 | ygfS | Putative electron transport protein YgfS | cofit | 37 | 97 |
| Escherichia coli ECRC62 | BNILDI_10070 | ygfS | Putative electron transport protein YgfS | insig. | 37 | 97 |
| Escherichia coli BW25113 | b2886 | ygfS | putative oxidoreductase, Fe-S subunit (VIMSS) | insig. | 37 | 97 |
| Escherichia coli BL21 | ECD_02359 | | putative oxidoreductase, FeS binding subunit/NAD/FAD-binding subunit | insig. | 38 | 89 |
| Escherichia coli ECRC101 | OKFHMN_21980 | aegA | formate-dependent uric acid utilization protein AegA | insig. | 38 | 89 |
| Escherichia coli ECRC101 | MCAODC_12510 | aegA | formate-dependent uric acid utilization protein AegA | insig. | 38 | 89 |
| Escherichia coli ECRC102 | NIAGMN_19750 | aegA | formate-dependent uric acid utilization protein AegA | insig. | 38 | 89 |
| Escherichia coli ECRC98 | JDDGAC_25925 | aegA | formate-dependent uric acid utilization protein AegA | no data | 38 | 89 |
| Escherichia coli ECRC99 | KEDOAH_06240 | aegA | formate-dependent uric acid utilization protein AegA | no data | 38 | 89 |
| Escherichia coli HS(pFamp)R (ATCC 700891) | OHPLBJKB_01263 | | Ferredoxin--NADP reductase | insig. | 38 | 89 |
| Escherichia coli BW25113 | b2468 | aegA | fused predicted oxidoreductase: FeS binding subunit/NAD/FAD-binding subunit (NCBI) | sig. | 38 | 89 |
| Escherichia coli BL21 | ECD_02718 | | putative 4Fe-4S ferredoxin-type oxidoreductase subunit | insig. | 37 | 97 |
| Escherichia coli HS(pFamp)R (ATCC 700891) | OHPLBJKB_00830 | | Hydrogenase-4 component A | insig. | 37 | 97 |
| Escherichia coli BL21 | ECD_02719 | | putative oxidoreductase, Fe-S subunit/nucleotide-binding subunit | insig. | 34 | 96 |
| Escherichia coli ECRC101 | OKFHMN_19610 | ygfT | formate-dependent uric acid utilization protein YgfT | insig. | 34 | 96 |
| Escherichia coli ECRC101 | MCAODC_10135 | ygfT | formate-dependent uric acid utilization protein YgfT | insig. | 34 | 96 |
| Escherichia coli ECRC102 | NIAGMN_17380 | ygfT | formate-dependent uric acid utilization protein YgfT | insig. | 34 | 96 |
| Escherichia coli ECRC62 | BNILDI_10065 | ygfT | formate-dependent uric acid utilization protein YgfT | insig. | 34 | 96 |
| Escherichia coli ECRC98 | JDDGAC_23255 | ygfT | formate-dependent uric acid utilization protein YgfT | no data | 34 | 96 |
| Escherichia coli ECRC99 | KEDOAH_08525 | ygfT | formate-dependent uric acid utilization protein YgfT | no data | 34 | 96 |
| Escherichia coli HS(pFamp)R (ATCC 700891) | OHPLBJKB_00829 | | Ferredoxin--NADP reductase | insig. | 34 | 96 |
| Escherichia coli BW25113 | b2887 | ygfT | putative oxidoreductase, Fe-S subunit (VIMSS) | insig. | 34 | 96 |
| Escherichia coli ECOR27 | NOLOHH_13660 | aegA | formate-dependent uric acid utilization protein AegA | cofit | 38 | 89 |
| Escherichia coli ECRC62 | BNILDI_12470 | aegA | formate-dependent uric acid utilization protein AegA | insig. | 38 | 89 |
| Enterobacter sp. TBS_079 | MPMX20_03329 | | Ferredoxin--NADP reductase | insig. | 35 | 91 |
| Escherichia fergusonii Becca | EFB2_01015 | | Ferredoxin--NADP reductase | insig. | 34 | 96 |
| Escherichia coli ECOR38 | HEPCGN_18900 | ygfT | formate-dependent uric acid utilization protein YgfT | cofit | 34 | 96 |
| Escherichia coli Nissle 1917 | ECOLIN_RS16080 | | formate-dependent uric acid utilization protein YgfT | insig. | 34 | 96 |
| Escherichia fergusonii Becca | EFB2_01420 | | Ferredoxin--NADP reductase | insig. | 38 | 89 |
| Escherichia coli Nissle 1917 | ECOLIN_RS14080 | | formate-dependent uric acid utilization protein AegA | cofit | 38 | 89 |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | GFF2190 | | Glutamate synthase [NADPH] small chain (EC 1.4.1.13) | insig. | 37 | 89 |
| Enterobacter asburiae PDN3 | EX28DRAFT_0193 | | glutamate synthase small subunit family protein, proteobacterial | insig. | 35 | 91 |
| Escherichia coli ECOR27 | NOLOHH_11540 | ygfT | formate-dependent uric acid utilization protein YgfT | cofit | 34 | 96 |
| Escherichia fergusonii Becca | EFB2_01016 | | Hydrogenase-4 component A | insig. | 36 | 97 |
| Escherichia coli Nissle 1917 | ECOLIN_RS16075 | | 4Fe-4S dicluster domain-containing protein | insig. | 36 | 97 |
| Serratia liquefaciens MT49 | IAI46_12495 | | electron transport protein HydN | no data | 35 | 91 |
| Klebsiella michiganensis M5al | BWI76_RS20850 | | oxidoreductase FeS-binding subunit | insig. | 36 | 91 |
| Dickeya dianthicola ME23 | DZA65_RS22605 | | formate-dependent uric acid utilization protein AegA | insig. | 36 | 89 |
| Dickeya dianthicola 67-19 | HGI48_RS21620 | | formate-dependent uric acid utilization protein AegA | insig. | 36 | 89 |
| Klebsiella michiganensis M5al | BWI76_RS27070 | | 4Fe-4S ferredoxin | insig. | 35 | 91 |
| Escherichia coli ECOR38 | HEPCGN_14795 | hycB | electron transporter | cofit | 36 | 89 |
| Escherichia fergusonii Becca | EFB2_00234 | | Hydrogenase-4 component A | insig. | 35 | 89 |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | GFF437 | | Electron transport protein HydN | insig. | 36 | 89 |
| Escherichia coli ECOR27 | NOLOHH_07850 | hycB | electron transporter | cofit | 34 | 89 |
| Escherichia coli Nissle 1917 | ECOLIN_RS20435 | | 4Fe-4S binding protein | insig. | 34 | 89 |
| Escherichia coli BL21 | ECD_02563 | | formate dehydrogenase-H, [4Fe-4S] ferredoxin subunit | insig. | 35 | 93 |
| Escherichia fergusonii Becca | EFB2_01211 | | Hydrogenase-4 component A | insig. | 35 | 93 |
| Escherichia coli ECOR27 | NOLOHH_12475 | hydN | electron transport protein HydN | cofit | 35 | 93 |
| Escherichia coli ECRC101 | OKFHMN_20630 | hydN | electron transport protein HydN | no data | 35 | 93 |
| Escherichia coli ECRC101 | MCAODC_11155 | hydN | electron transport protein HydN | insig. | 35 | 93 |