Conservation of cofitness between ECD_04266 and ECD_03826 in Escherichia coli BL21

24 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BL21 1.0 ECD_04266 trifunctional protein: nicotinamide mononucleotide adenylyltransferase, ribosylnicotinamide kinase, transcriptional repressor 1.0 ECD_03826 Bifunctional aspartokinase/homoserine dehydrogenase 2 0.61 13
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_03671 Trifunctional NAD biosynthesis/regulator protein NadR 1.00 OHPLBJKB_04110 Bifunctional aspartokinase/homoserine dehydrogenase 2 low > 73
Escherichia coli ECOR27 1.00 NOLOHH_03515 nadR multifunctional transcriptional regulator/nicotinamide-nucleotide adenylyltransferase/ribosylnicotinamide kinase NadR 1.00 NOLOHH_05815 metL bifunctional aspartate kinase/homoserine dehydrogenase II low > 75
Escherichia coli ECRC62 1.00 BNILDI_08080 nadR multifunctional transcriptional regulator/nicotinamide-nucleotide adenylyltransferase/ribosylnicotinamide kinase NadR 1.00 BNILDI_05720 metL bifunctional aspartate kinase/homoserine dehydrogenase II low > 75
Escherichia coli ECOR38 1.00 HEPCGN_09190 nadR multifunctional transcriptional regulator/nicotinamide-nucleotide adenylyltransferase/ribosylnicotinamide kinase NadR 1.00 HEPCGN_12340 metL bifunctional aspartate kinase/homoserine dehydrogenase II low > 87
Escherichia coli Nissle 1917 1.00 ECOLIN_RS25195 multifunctional transcriptional regulator/nicotinamide-nucleotide adenylyltransferase/ribosylnicotinamide kinase NadR 0.99 ECOLIN_RS22730 bifunctional aspartate kinase/homoserine dehydrogenase II 0.42 42
Escherichia fergusonii Becca 1.00 EFB2_04056 Trifunctional NAD biosynthesis/regulator protein NadR 0.99 EFB2_04678 Bifunctional aspartokinase/homoserine dehydrogenase 2 low > 86
Escherichia coli BW25113 1.00 b4390 nadR probable nadAB transcriptional regulator (VIMSS) 1.00 b3940 metL bifunctional aspartate kinase II/homoserine dehydrogenase II (NCBI) low > 76
Escherichia coli ECRC98 1.00 JDDGAC_14785 nadR multifunctional transcriptional regulator/nicotinamide-nucleotide adenylyltransferase/ribosylnicotinamide kinase NadR 1.00 JDDGAC_17295 metL bifunctional aspartate kinase/homoserine dehydrogenase II low > 86
Escherichia coli ECRC101 1.00 MCAODC_01705 nadR multifunctional transcriptional regulator/nicotinamide-nucleotide adenylyltransferase/ribosylnicotinamide kinase NadR 1.00 MCAODC_04170 metL bifunctional aspartate kinase/homoserine dehydrogenase II low > 87
Escherichia coli ECRC102 1.00 NIAGMN_09040 nadR multifunctional transcriptional regulator/nicotinamide-nucleotide adenylyltransferase/ribosylnicotinamide kinase NadR 1.00 NIAGMN_11425 metL bifunctional aspartate kinase/homoserine dehydrogenase II — —
Escherichia coli ECRC99 1.00 KEDOAH_16965 nadR multifunctional transcriptional regulator/nicotinamide-nucleotide adenylyltransferase/ribosylnicotinamide kinase NadR 1.00 KEDOAH_14490 metL bifunctional aspartate kinase/homoserine dehydrogenase II — —
Escherichia coli ECRC100 1.00 OKFHMN_11190 nadR multifunctional transcriptional regulator/nicotinamide-nucleotide adenylyltransferase/ribosylnicotinamide kinase NadR 1.00 OKFHMN_13670 metL bifunctional aspartate kinase/homoserine dehydrogenase II low > 80
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.95 GFF1058 NadR transcriptional regulator / Nicotinamide-nucleotide adenylyltransferase, NadR family (EC 2.7.7.1) / Ribosylnicotinamide kinase (EC 2.7.1.22) 0.94 GFF2324 Aspartokinase (EC 2.7.2.4) / Homoserine dehydrogenase (EC 1.1.1.3) low > 78
Enterobacter asburiae PDN3 0.94 EX28DRAFT_3598 nicotinamide-nucleotide adenylyltransferase, NadR type 0.93 EX28DRAFT_4412 aspartate kinase (EC 2.7.2.4) low > 76
Enterobacter sp. TBS_079 0.93 MPMX20_00695 Trifunctional NAD biosynthesis/regulator protein NadR 0.93 MPMX20_04530 Bifunctional aspartokinase/homoserine dehydrogenase 2 low > 85
Klebsiella michiganensis M5al 0.92 BWI76_RS04170 trifunctional nicotinamide-nucleotide adenylyltransferase/ribosylnicotinamide kinase/transcriptional regulator NadR 0.92 BWI76_RS00790 bifunctional aspartokinase II/homoserine dehydrogenase II low > 92
Erwinia tracheiphila SCR3 0.89 LU632_RS02555 nadR multifunctional transcriptional regulator/nicotinamide-nucleotide adenylyltransferase/ribosylnicotinamide kinase NadR 0.82 LU632_RS19635 bifunctional aspartate kinase/homoserine dehydrogenase II low > 74
Pantoea sp. MT58 0.89 IAI47_16340 multifunctional transcriptional regulator/nicotinamide-nucleotide adenylyltransferase/ribosylnicotinamide kinase NadR 0.85 IAI47_00885 bifunctional aspartate kinase/homoserine dehydrogenase II low > 76
Dickeya dadantii 3937 0.88 DDA3937_RS02415 multifunctional transcriptional regulator/nicotinamide-nucleotide adenylyltransferase/ribosylnicotinamide kinase NadR 0.83 DDA3937_RS00955 bifunctional aspartate kinase/homoserine dehydrogenase II low > 74
Rahnella sp. WP5 0.88 EX31_RS04025 multifunctional transcriptional regulator/nicotinamide-nucleotide adenylyltransferase/ribosylnicotinamide kinase NadR 0.84 EX31_RS14210 bifunctional aspartate kinase/homoserine dehydrogenase II low > 89
Dickeya dianthicola ME23 0.88 DZA65_RS02480 multifunctional transcriptional regulator/nicotinamide-nucleotide adenylyltransferase/ribosylnicotinamide kinase NadR 0.83 DZA65_RS21465 bifunctional aspartate kinase/homoserine dehydrogenase II low > 75
Dickeya dianthicola 67-19 0.88 HGI48_RS02375 multifunctional transcriptional regulator/nicotinamide-nucleotide adenylyltransferase/ribosylnicotinamide kinase NadR 0.83 HGI48_RS20420 bifunctional aspartate kinase/homoserine dehydrogenase II 0.61 70
Pectobacterium carotovorum WPP14 0.86 HER17_RS19090 multifunctional transcriptional regulator/nicotinamide-nucleotide adenylyltransferase/ribosylnicotinamide kinase NadR 0.82 HER17_RS00915 bifunctional aspartate kinase/homoserine dehydrogenase II 0.47 51
Serratia liquefaciens MT49 0.84 IAI46_02950 multifunctional transcriptional regulator/nicotinamide-nucleotide adenylyltransferase/ribosylnicotinamide kinase NadR 0.84 IAI46_24535 bifunctional aspartate kinase/homoserine dehydrogenase II 0.53 33

Not shown: 2 genomes with orthologs for ECD_04266 only; 6 genomes with orthologs for ECD_03826 only