Conservation of cofitness between BWI76_RS22090 and BWI76_RS04170 in Klebsiella michiganensis M5al

24 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Klebsiella michiganensis M5al 1.0 BWI76_RS22090 transcriptional regulator 1.0 BWI76_RS04170 trifunctional nicotinamide-nucleotide adenylyltransferase/ribosylnicotinamide kinase/transcriptional regulator NadR 0.41 10
Enterobacter sp. TBS_079 0.96 MPMX20_03562 Transcriptional repressor MprA 0.93 MPMX20_00695 Trifunctional NAD biosynthesis/regulator protein NadR low > 85
Enterobacter asburiae PDN3 0.96 EX28DRAFT_2767 Transcriptional regulators 0.94 EX28DRAFT_3598 nicotinamide-nucleotide adenylyltransferase, NadR type — —
Escherichia coli ECOR38 0.95 HEPCGN_19985 emrR multidrug efflux transporter EmrAB transcriptional repressor EmrR 0.92 HEPCGN_09190 nadR multifunctional transcriptional regulator/nicotinamide-nucleotide adenylyltransferase/ribosylnicotinamide kinase NadR low > 87
Escherichia coli ECRC98 0.95 JDDGAC_24450 emrR multidrug efflux transporter EmrAB transcriptional repressor EmrR 0.92 JDDGAC_14785 nadR multifunctional transcriptional regulator/nicotinamide-nucleotide adenylyltransferase/ribosylnicotinamide kinase NadR low > 86
Escherichia coli HS(pFamp)R (ATCC 700891) 0.95 OHPLBJKB_01049 Transcriptional repressor MprA 0.92 OHPLBJKB_03671 Trifunctional NAD biosynthesis/regulator protein NadR low > 73
Escherichia coli ECRC100 0.95 OKFHMN_20785 emrR multidrug efflux transporter EmrAB transcriptional repressor EmrR 0.92 OKFHMN_11190 nadR multifunctional transcriptional regulator/nicotinamide-nucleotide adenylyltransferase/ribosylnicotinamide kinase NadR low > 80
Escherichia coli BW25113 0.95 b2684 mprA DNA-binding transcriptional repressor of microcin B17 synthesis and multidrug efflux (NCBI) 0.92 b4390 nadR probable nadAB transcriptional regulator (VIMSS) low > 76
Escherichia coli ECOR27 0.95 NOLOHH_12625 emrR multidrug efflux transporter EmrAB transcriptional repressor EmrR 0.92 NOLOHH_03515 nadR multifunctional transcriptional regulator/nicotinamide-nucleotide adenylyltransferase/ribosylnicotinamide kinase NadR low > 75
Escherichia coli BL21 0.95 ECD_02539 transcriptional repressor of microcin B17 synthesis and multidrug efflux 0.92 ECD_04266 trifunctional protein: nicotinamide mononucleotide adenylyltransferase, ribosylnicotinamide kinase, transcriptional repressor low > 61
Escherichia coli Nissle 1917 0.95 ECOLIN_RS14960 multidrug efflux transporter EmrAB transcriptional repressor EmrR 0.92 ECOLIN_RS25195 multifunctional transcriptional regulator/nicotinamide-nucleotide adenylyltransferase/ribosylnicotinamide kinase NadR low > 55
Escherichia fergusonii Becca 0.95 EFB2_01244 Transcriptional repressor MprA 0.92 EFB2_04056 Trifunctional NAD biosynthesis/regulator protein NadR low > 86
Escherichia coli ECRC102 0.95 NIAGMN_18555 emrR multidrug efflux transporter EmrAB transcriptional repressor EmrR 0.92 NIAGMN_09040 nadR multifunctional transcriptional regulator/nicotinamide-nucleotide adenylyltransferase/ribosylnicotinamide kinase NadR — —
Escherichia coli ECRC99 0.95 KEDOAH_07350 emrR multidrug efflux transporter EmrAB transcriptional repressor EmrR 0.92 KEDOAH_16965 nadR multifunctional transcriptional regulator/nicotinamide-nucleotide adenylyltransferase/ribosylnicotinamide kinase NadR — —
Escherichia coli ECRC101 0.94 MCAODC_11310 emrR multidrug efflux transporter EmrAB transcriptional repressor EmrR 0.92 MCAODC_01705 nadR multifunctional transcriptional regulator/nicotinamide-nucleotide adenylyltransferase/ribosylnicotinamide kinase NadR low > 87
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.94 GFF1591 Transcription repressor of tripartite multidrug resistance system 0.94 GFF1058 NadR transcriptional regulator / Nicotinamide-nucleotide adenylyltransferase, NadR family (EC 2.7.7.1) / Ribosylnicotinamide kinase (EC 2.7.1.22) 0.70 4
Escherichia coli ECRC62 0.94 BNILDI_11185 emrR multidrug efflux transporter EmrAB transcriptional repressor EmrR 0.92 BNILDI_08080 nadR multifunctional transcriptional regulator/nicotinamide-nucleotide adenylyltransferase/ribosylnicotinamide kinase NadR low > 75
Pantoea sp. MT58 0.81 IAI47_04505 transcriptional repressor MprA 0.89 IAI47_16340 multifunctional transcriptional regulator/nicotinamide-nucleotide adenylyltransferase/ribosylnicotinamide kinase NadR low > 76
Erwinia tracheiphila SCR3 0.80 LU632_RS16835 mprA transcriptional repressor MprA 0.88 LU632_RS02555 nadR multifunctional transcriptional regulator/nicotinamide-nucleotide adenylyltransferase/ribosylnicotinamide kinase NadR low > 74
Serratia liquefaciens MT49 0.78 IAI46_19990 transcriptional repressor MprA 0.84 IAI46_02950 multifunctional transcriptional regulator/nicotinamide-nucleotide adenylyltransferase/ribosylnicotinamide kinase NadR low > 86
Rahnella sp. WP5 0.76 EX31_RS13645 transcriptional repressor MprA 0.88 EX31_RS04025 multifunctional transcriptional regulator/nicotinamide-nucleotide adenylyltransferase/ribosylnicotinamide kinase NadR low > 89
Dickeya dianthicola 67-19 0.71 HGI48_RS16825 transcriptional repressor MprA 0.87 HGI48_RS02375 multifunctional transcriptional regulator/nicotinamide-nucleotide adenylyltransferase/ribosylnicotinamide kinase NadR low > 71
Dickeya dadantii 3937 0.70 DDA3937_RS16755 transcriptional repressor MprA 0.88 DDA3937_RS02415 multifunctional transcriptional regulator/nicotinamide-nucleotide adenylyltransferase/ribosylnicotinamide kinase NadR low > 74
Dickeya dianthicola ME23 0.70 DZA65_RS17900 transcriptional repressor MprA 0.87 DZA65_RS02480 multifunctional transcriptional regulator/nicotinamide-nucleotide adenylyltransferase/ribosylnicotinamide kinase NadR low > 75
Pectobacterium carotovorum WPP14 0.69 HER17_RS04470 transcriptional repressor MprA 0.87 HER17_RS19090 multifunctional transcriptional regulator/nicotinamide-nucleotide adenylyltransferase/ribosylnicotinamide kinase NadR low > 75

Not shown: 5 genomes with orthologs for BWI76_RS22090 only; 2 genomes with orthologs for BWI76_RS04170 only