Conservation of cofitness between BWI76_RS04170 and BWI76_RS02545 in Klebsiella michiganensis M5al

24 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Klebsiella michiganensis M5al 1.0 BWI76_RS04170 trifunctional nicotinamide-nucleotide adenylyltransferase/ribosylnicotinamide kinase/transcriptional regulator NadR 1.0 BWI76_RS02545 protease modulator HflK 0.41 18
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.94 GFF1058 NadR transcriptional regulator / Nicotinamide-nucleotide adenylyltransferase, NadR family (EC 2.7.7.1) / Ribosylnicotinamide kinase (EC 2.7.1.22) 0.78 GFF827 HflK protein low > 78
Enterobacter asburiae PDN3 0.94 EX28DRAFT_3598 nicotinamide-nucleotide adenylyltransferase, NadR type 0.82 EX28DRAFT_3371 HflK protein low > 76
Enterobacter sp. TBS_079 0.93 MPMX20_00695 Trifunctional NAD biosynthesis/regulator protein NadR 0.76 MPMX20_00455 Modulator of FtsH protease HflK low > 85
Escherichia coli BW25113 0.92 b4390 nadR probable nadAB transcriptional regulator (VIMSS) 0.78 b4174 hflK modulator for HflB protease specific for phage lambda cII repressor (NCBI) 0.35 1
Escherichia coli ECOR38 0.92 HEPCGN_09190 nadR multifunctional transcriptional regulator/nicotinamide-nucleotide adenylyltransferase/ribosylnicotinamide kinase NadR 0.78 HEPCGN_10475 hflK FtsH protease activity modulator HflK low > 87
Escherichia coli Nissle 1917 0.92 ECOLIN_RS25195 multifunctional transcriptional regulator/nicotinamide-nucleotide adenylyltransferase/ribosylnicotinamide kinase NadR 0.78 ECOLIN_RS24240 FtsH protease activity modulator HflK low > 55
Escherichia coli ECRC99 0.92 KEDOAH_16965 nadR multifunctional transcriptional regulator/nicotinamide-nucleotide adenylyltransferase/ribosylnicotinamide kinase NadR 0.77 KEDOAH_15910 hflK FtsH protease activity modulator HflK — —
Escherichia coli ECRC100 0.92 OKFHMN_11190 nadR multifunctional transcriptional regulator/nicotinamide-nucleotide adenylyltransferase/ribosylnicotinamide kinase NadR 0.78 OKFHMN_12245 hflK FtsH protease activity modulator HflK low > 80
Escherichia coli ECRC102 0.92 NIAGMN_09040 nadR multifunctional transcriptional regulator/nicotinamide-nucleotide adenylyltransferase/ribosylnicotinamide kinase NadR 0.78 NIAGMN_10095 hflK FtsH protease activity modulator HflK — —
Escherichia coli ECRC98 0.92 JDDGAC_14785 nadR multifunctional transcriptional regulator/nicotinamide-nucleotide adenylyltransferase/ribosylnicotinamide kinase NadR 0.78 JDDGAC_15885 hflK FtsH protease activity modulator HflK low > 86
Escherichia coli ECRC101 0.92 MCAODC_01705 nadR multifunctional transcriptional regulator/nicotinamide-nucleotide adenylyltransferase/ribosylnicotinamide kinase NadR 0.78 MCAODC_02760 hflK FtsH protease activity modulator HflK low > 87
Escherichia fergusonii Becca 0.92 EFB2_04056 Trifunctional NAD biosynthesis/regulator protein NadR 0.80 EFB2_04361 Modulator of FtsH protease HflK low > 86
Escherichia coli HS(pFamp)R (ATCC 700891) 0.92 OHPLBJKB_03671 Trifunctional NAD biosynthesis/regulator protein NadR 0.78 OHPLBJKB_03868 Modulator of FtsH protease HflK low > 73
Escherichia coli ECRC62 0.92 BNILDI_08080 nadR multifunctional transcriptional regulator/nicotinamide-nucleotide adenylyltransferase/ribosylnicotinamide kinase NadR 0.78 BNILDI_06980 hflK FtsH protease activity modulator HflK low > 75
Escherichia coli BL21 0.92 ECD_04266 trifunctional protein: nicotinamide mononucleotide adenylyltransferase, ribosylnicotinamide kinase, transcriptional repressor 0.78 ECD_04041 modulator for HflB protease specific for phage lambda cII repressor low > 61
Escherichia coli ECOR27 0.92 NOLOHH_03515 nadR multifunctional transcriptional regulator/nicotinamide-nucleotide adenylyltransferase/ribosylnicotinamide kinase NadR 0.78 NOLOHH_04510 hflK FtsH protease activity modulator HflK low > 75
Pantoea sp. MT58 0.89 IAI47_16340 multifunctional transcriptional regulator/nicotinamide-nucleotide adenylyltransferase/ribosylnicotinamide kinase NadR 0.68 IAI47_02600 FtsH protease activity modulator HflK 0.63 1
Rahnella sp. WP5 0.88 EX31_RS04025 multifunctional transcriptional regulator/nicotinamide-nucleotide adenylyltransferase/ribosylnicotinamide kinase NadR 0.65 EX31_RS08810 FtsH protease activity modulator HflK 0.32 70
Dickeya dadantii 3937 0.88 DDA3937_RS02415 multifunctional transcriptional regulator/nicotinamide-nucleotide adenylyltransferase/ribosylnicotinamide kinase NadR 0.70 DDA3937_RS18600 FtsH protease activity modulator HflK low > 74
Erwinia tracheiphila SCR3 0.88 LU632_RS02555 nadR multifunctional transcriptional regulator/nicotinamide-nucleotide adenylyltransferase/ribosylnicotinamide kinase NadR 0.69 LU632_RS02065 hflK FtsH protease activity modulator HflK 0.64 11
Dickeya dianthicola ME23 0.87 DZA65_RS02480 multifunctional transcriptional regulator/nicotinamide-nucleotide adenylyltransferase/ribosylnicotinamide kinase NadR 0.70 DZA65_RS19670 FtsH protease activity modulator HflK low > 75
Dickeya dianthicola 67-19 0.87 HGI48_RS02375 multifunctional transcriptional regulator/nicotinamide-nucleotide adenylyltransferase/ribosylnicotinamide kinase NadR 0.69 HGI48_RS18535 FtsH protease activity modulator HflK low > 71
Pectobacterium carotovorum WPP14 0.87 HER17_RS19090 multifunctional transcriptional regulator/nicotinamide-nucleotide adenylyltransferase/ribosylnicotinamide kinase NadR 0.72 HER17_RS02595 FtsH protease activity modulator HflK low > 75
Serratia liquefaciens MT49 0.84 IAI46_02950 multifunctional transcriptional regulator/nicotinamide-nucleotide adenylyltransferase/ribosylnicotinamide kinase NadR 0.67 IAI46_01635 FtsH protease activity modulator HflK 0.65 2

Not shown: 2 genomes with orthologs for BWI76_RS04170 only; 40 genomes with orthologs for BWI76_RS02545 only