Conservation of cofitness between b2218 and b3755 in Escherichia coli BW25113

20 genomes with putative orthologs of both genes

Organism	Ratio1	Gene1	Name1	Description1	Ratio2	Gene2	Name2	Description2	Cofit	Rank
Escherichia coli BW25113	1.0	b2218	rcsC	hybrid sensory kinase in two-component regulatory system with RcsB and YojN (RefSeq)	1.0	b3755	yieP	predicted transcriptional regulator (NCBI)	0.41	11
Escherichia coli BL21	1.00	ECD_02145		hybrid sensory kinase in two-component regulatory system with RcsB and YojN	1.00	ECD_03641		putative transcriptional regulator	low	> 60
Escherichia coli HS(pFamp)R (ATCC 700891)	1.00	OHPLBJKB_01492		Sensor histidine kinase RcsC	0.99	OHPLBJKB_04295		HTH-type transcriptional repressor NanR	0.44	20
Escherichia coli ECOR27	1.00	NOLOHH_14745	rcsC	two-component system sensor histidine kinase RcsC	1.00	NOLOHH_06850	yieP	Uncharacterized HTH-type transcriptional regulator YieP	low	> 57
Escherichia coli ECRC62	1.00	BNILDI_13665	rcsC	two-component system sensor histidine kinase RcsC	1.00	BNILDI_04675	yieP	Uncharacterized HTH-type transcriptional regulator YieP	—	—
Escherichia coli Nissle 1917	1.00	ECOLIN_RS12955		two-component system sensor histidine kinase RcsC	1.00	ECOLIN_RS21595		FadR/GntR family transcriptional regulator	low	> 52
Escherichia fergusonii Becca	1.00	EFB2_01637		Sensor histidine kinase RcsC	1.00	EFB2_04878		HTH-type transcriptional repressor NanR	low	> 86
Escherichia coli ECOR38	1.00	HEPCGN_22440	rcsC	two-component system sensor histidine kinase RcsC	1.00	HEPCGN_13425	yieP	Uncharacterized HTH-type transcriptional regulator YieP	0.86	70
Escherichia coli ECRC101	0.99	OKFHMN_23170	rcsC	two-component system sensor histidine kinase RcsC	1.00	OKFHMN_14715	yieP	Uncharacterized HTH-type transcriptional regulator YieP	—	—
Escherichia coli ECRC102	0.99	NIAGMN_20935	rcsC	two-component system sensor histidine kinase RcsC	1.00	NIAGMN_12470	yieP	Uncharacterized HTH-type transcriptional regulator YieP	—	—
Escherichia coli ECRC98	0.99	JDDGAC_27130	rcsC	two-component system sensor histidine kinase RcsC	1.00	JDDGAC_18335	yieP	Uncharacterized HTH-type transcriptional regulator YieP	—	—
Escherichia coli ECRC99	0.99	KEDOAH_05015	rcsC	two-component system sensor histidine kinase RcsC	1.00	KEDOAH_13435	yieP	Uncharacterized HTH-type transcriptional regulator YieP	—	—
Escherichia coli ECRC101	0.99	MCAODC_14220	rcsC	two-component system sensor histidine kinase RcsC	1.00	MCAODC_05220	yieP	Uncharacterized HTH-type transcriptional regulator YieP	—	—
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868	0.89	GFF1832		Two-component sensor protein RcsC (EC 2.7.3.-)	0.87	GFF1702		Transcriptional regulator, GntR family	low	> 78
Enterobacter asburiae PDN3	0.85	EX28DRAFT_0357		Signal transduction histidine kinase	0.86	EX28DRAFT_4031		Transcriptional regulators	low	> 76
Enterobacter sp. TBS_079	0.85	MPMX20_03178		Sensor histidine kinase RcsC	0.85	MPMX20_04612		HTH-type transcriptional repressor NanR	low	> 85
Klebsiella michiganensis M5al	0.81	BWI76_RS19920		hybrid sensor histidine kinase/response regulator	0.80	BWI76_RS00305		GntR family transcriptional regulator	low	> 92
Serratia liquefaciens MT49	0.62	IAI46_17455		two-component system sensor histidine kinase RcsC	0.63	IAI46_25040		FadR family transcriptional regulator	low	> 86
Rahnella sp. WP5	0.61	EX31_RS19285		two-component system sensor histidine kinase RcsC	0.62	EX31_RS06200		FadR family transcriptional regulator	low	> 89
Pseudomonas fluorescens SBW25	0.18	PFLU_RS07890		response regulator	0.18	PFLU_RS20920		FadR family transcriptional regulator	low	> 109
Pseudomonas fluorescens SBW25-INTG	0.18	PFLU_RS07890		response regulator	0.18	PFLU_RS20920		FadR family transcriptional regulator	low	> 109

Not shown: 7 genomes with orthologs for b2218 only; 9 genomes with orthologs for b3755 only