Conservation of cofitness between b0446 and b1811 in Escherichia coli BW25113

18 genomes with putative orthologs of both genes

Organism	Ratio1	Gene1	Name1	Description1	Ratio2	Gene2	Name2	Description2	Cofit	Rank
Escherichia coli BW25113	1.0	b0446	cof	orf, hypothetical protein (VIMSS)	1.0	b1811	yoaH	hypothetical protein (NCBI)	0.24	3
Escherichia coli ECOR27	0.99	NOLOHH_01220	cof	HMP-PP phosphatase	1.00	NOLOHH_17085	yoaH	YoaH family protein	—	—
Escherichia coli BL21	0.99	ECD_00398		thiamine pyrimidine pyrophosphate hydrolase; HMP-PP phosphatase	1.00	ECD_01781		UPF0181 family protein	—	—
Escherichia coli HS(pFamp)R (ATCC 700891)	0.99	OHPLBJKB_03227		HMP-PP phosphatase	1.00	OHPLBJKB_01920		hypothetical protein	—	—
Escherichia coli ECRC62	0.99	BNILDI_22635	cof	HMP-PP phosphatase	1.00	BNILDI_15870	yoaH	YoaH family protein	—	—
Escherichia coli ECOR38	0.99	HEPCGN_06900	cof	HMP-PP phosphatase	1.00	HEPCGN_04955	yoaH	YoaH family protein	—	—
Escherichia fergusonii Becca	0.99	EFB2_03611		HMP-PP phosphatase	1.00	EFB2_02189		hypothetical protein	—	—
Escherichia coli ECRC98	0.99	JDDGAC_11940	cof	HMP-PP phosphatase	1.00	JDDGAC_01140	yoaH	YoaH family protein	—	—
Escherichia coli ECRC99	0.99	KEDOAH_19680	cof	HMP-PP phosphatase	1.00	KEDOAH_01545	yoaH	YoaH family protein	—	—
Escherichia coli ECRC102	0.99	NIAGMN_06340	cof	HMP-PP phosphatase	1.00	NIAGMN_01500	yoaH	YoaH family protein	—	—
Escherichia coli ECRC101	0.99	MCAODC_27510	cof	HMP-PP phosphatase	1.00	MCAODC_18845	yoaH	YoaH family protein	—	—
Escherichia coli Nissle 1917	0.99	ECOLIN_RS02670		HMP-PP phosphatase	1.00	ECOLIN_RS10075		YoaH family protein	—	—
Escherichia coli ECRC101	0.99	OKFHMN_08285	cof	HMP-PP phosphatase	1.00	OKFHMN_26565	yoaH	YoaH family protein	—	—
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868	0.83	GFF4362		HMP-PP hydrolase (pyridoxal phosphatase) Cof, detected in genetic screen for thiamin metabolic genes (PMID:15292217)	0.92	GFF2825		FIG00638134: hypothetical protein	low	> 78
Enterobacter sp. TBS_079	0.80	MPMX20_01037		HMP-PP phosphatase	0.86	MPMX20_02716		hypothetical protein	low	> 85
Klebsiella michiganensis M5al	0.79	BWI76_RS06570		thiamin pyrimidine pyrophosphate hydrolase	0.93	BWI76_RS17860		YoaH family protein	low	> 92
Enterobacter asburiae PDN3	0.79	EX28DRAFT_2524		HAD-superfamily hydrolase, subfamily IIB	0.84	EX28DRAFT_0748		Uncharacterized protein conserved in bacteria	—	—
Pantoea sp. MT58	0.61	IAI47_14610		HMP-PP phosphatase	0.67	IAI47_08800		YoaH family protein	low	> 76
Rahnella sp. WP5	0.59	EX31_RS22290		HMP-PP phosphatase	0.64	EX31_RS24730		YoaH family protein	low	> 89

Not shown: 1 genomes with orthologs for b0446 only; 4 genomes with orthologs for b1811 only