Conservation of cofitness between b4266 and b1619 in Escherichia coli BW25113

13 genomes with putative orthologs of both genes

Organism	Ratio1	Gene1	Name1	Description1	Ratio2	Gene2	Name2	Description2	Cofit	Rank
Escherichia coli BW25113	1.0	b4266	idnO	gluconate 5-dehydrogenase (NCBI)	1.0	b1619	hdhA	7-alpha-hydroxysteroid dehydrogenase (NCBI)	0.17	17
Escherichia coli HS(pFamp)R (ATCC 700891)	1.00	OHPLBJKB_03770		5-keto-D-gluconate 5-reductase	1.00	OHPLBJKB_02107		7-alpha-hydroxysteroid dehydrogenase	low	> 73
Escherichia coli BL21	1.00	ECD_04132		5-keto-D-gluconate-5-reductase	1.00	ECD_01588		7-alpha-hydroxysteroid dehydrogenase, NAD-dependent	—	—
Escherichia coli ECOR27	1.00	NOLOHH_04025	idnO	gluconate 5-dehydrogenase	1.00	NOLOHH_18115	hdhA	7-alpha-hydroxysteroid dehydrogenase	—	—
Escherichia fergusonii Becca	1.00	EFB2_04269		5-keto-D-gluconate 5-reductase	0.99	EFB2_02373		7-alpha-hydroxysteroid dehydrogenase	low	> 86
Escherichia coli ECOR38	0.99	HEPCGN_09950	idnO	gluconate 5-dehydrogenase	0.99	HEPCGN_05985	hdhA	7-alpha-hydroxysteroid dehydrogenase	low	> 85
Bosea sp. OAE506	0.58	ABIE41_RS09610		SDR family NAD(P)-dependent oxidoreductase	0.31	ABIE41_RS11110		SDR family oxidoreductase	low	> 77
Herbaspirillum seropedicae SmR1	0.56	HSERO_RS05480		gluconate 5-dehydrogenase	0.26	HSERO_RS11255		3-ketoacyl-ACP reductase	low	> 78
Bacteroides thetaiotaomicron VPI-5482	0.47	BT3232		gluconate 5-dehydrogenase (NCBI ptt file)	0.28	BT1911		7-alpha-hydroxysteroid dehydrogenase (NCBI ptt file)	low	> 81
Bacteroides ovatus ATCC 8483	0.46	BACOVA_00141		oxidoreductase, short chain dehydrogenase/reductase family protein	0.27	BACOVA_01473		oxidoreductase, short chain dehydrogenase/reductase family protein	low	> 94
Escherichia coli Nissle 1917	0.45	ECOLIN_RS01525		gluconate 5-dehydrogenase	0.99	ECOLIN_RS09035		7-alpha-hydroxysteroid dehydrogenase	—	—
Paraburkholderia sabiae LMG 24235	0.41	QEN71_RS20310		SDR family oxidoreductase	0.28	QEN71_RS24930		SDR family oxidoreductase	low	> 153
Cupriavidus basilensis FW507-4G11	0.32	RR42_RS21135		gluconate 5-dehydrogenase	0.31	RR42_RS28985		short-chain dehydrogenase	0.26	33
Dinoroseobacter shibae DFL-12	0.28	Dshi_0553		short-chain dehydrogenase/reductase SDR (RefSeq)	0.31	Dshi_1429		short-chain dehydrogenase/reductase SDR (RefSeq)	low	> 64

Not shown: 27 genomes with orthologs for b4266 only; 24 genomes with orthologs for b1619 only