Conservation of cofitness between b0446 and b0101 in Escherichia coli BW25113

19 genomes with putative orthologs of both genes

Organism	Ratio1	Gene1	Name1	Description1	Ratio2	Gene2	Name2	Description2	Cofit	Rank
Escherichia coli BW25113	1.0	b0446	cof	orf, hypothetical protein (VIMSS)	1.0	b0101	yacG	zinc-binding protein (NCBI)	0.21	11
Escherichia coli ECOR27	0.99	NOLOHH_01220	cof	HMP-PP phosphatase	1.00	NOLOHH_02915	yacG	DNA gyrase inhibitor YacG	—	—
Escherichia coli HS(pFamp)R (ATCC 700891)	0.99	OHPLBJKB_03227		HMP-PP phosphatase	1.00	OHPLBJKB_03559		DNA gyrase inhibitor YacG	—	—
Escherichia coli BL21	0.99	ECD_00398		thiamine pyrimidine pyrophosphate hydrolase; HMP-PP phosphatase	1.00	ECD_00101		DNA gyrase inhibitor	—	—
Escherichia coli ECOR38	0.99	HEPCGN_06900	cof	HMP-PP phosphatase	1.00	HEPCGN_08550	yacG	DNA gyrase inhibitor YacG	—	—
Escherichia coli ECRC62	0.99	BNILDI_22635	cof	HMP-PP phosphatase	1.00	BNILDI_08695	yacG	DNA gyrase inhibitor YacG	—	—
Escherichia fergusonii Becca	0.99	EFB2_03611		HMP-PP phosphatase	1.00	EFB2_03947		DNA gyrase inhibitor YacG	—	—
Escherichia coli ECRC101	0.99	OKFHMN_08285	cof	HMP-PP phosphatase	1.00	OKFHMN_10570	yacG	DNA gyrase inhibitor YacG	—	—
Escherichia coli ECRC101	0.99	MCAODC_27510	cof	HMP-PP phosphatase	1.00	MCAODC_01085	yacG	DNA gyrase inhibitor YacG	—	—
Escherichia coli ECRC102	0.99	NIAGMN_06340	cof	HMP-PP phosphatase	1.00	NIAGMN_08420	yacG	DNA gyrase inhibitor YacG	—	—
Escherichia coli Nissle 1917	0.99	ECOLIN_RS02670		HMP-PP phosphatase	0.99	ECOLIN_RS00545		DNA gyrase inhibitor YacG	—	—
Escherichia coli ECRC98	0.99	JDDGAC_11940	cof	HMP-PP phosphatase	1.00	JDDGAC_14165	yacG	DNA gyrase inhibitor YacG	—	—
Escherichia coli ECRC99	0.99	KEDOAH_19680	cof	HMP-PP phosphatase	1.00	KEDOAH_17585	yacG	DNA gyrase inhibitor YacG	—	—
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868	0.83	GFF4362		HMP-PP hydrolase (pyridoxal phosphatase) Cof, detected in genetic screen for thiamin metabolic genes (PMID:15292217)	0.68	GFF137		FIG003276: zinc-binding protein	—	—
Enterobacter sp. TBS_079	0.80	MPMX20_01037		HMP-PP phosphatase	0.83	MPMX20_00793		DNA gyrase inhibitor YacG	low	> 85
Klebsiella michiganensis M5al	0.79	BWI76_RS06570		thiamin pyrimidine pyrophosphate hydrolase	0.84	BWI76_RS04810		DNA gyrase inhibitor YacG	—	—
Enterobacter asburiae PDN3	0.79	EX28DRAFT_2524		HAD-superfamily hydrolase, subfamily IIB	0.85	EX28DRAFT_3695		Uncharacterized protein conserved in bacteria	—	—
Serratia liquefaciens MT49	0.61	IAI46_05055		HMP-PP phosphatase	0.77	IAI46_03495		DNA gyrase inhibitor YacG	—	—
Pantoea sp. MT58	0.61	IAI47_14610		HMP-PP phosphatase	0.77	IAI47_15880		DNA gyrase inhibitor YacG	low	> 76
Rahnella sp. WP5	0.59	EX31_RS22290		HMP-PP phosphatase	0.77	EX31_RS03550		DNA gyrase inhibitor YacG	low	> 89

Not shown: 0 genomes with orthologs for b0446 only; 22 genomes with orthologs for b0101 only