Conservation of cofitness between GFF4362 and GFF3663 in Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

17 genomes with putative orthologs of both genes

Organism	Ratio1	Gene1	Name1	Description1	Ratio2	Gene2	Name2	Description2	Cofit	Rank
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868	1.0	GFF4362		HMP-PP hydrolase (pyridoxal phosphatase) Cof, detected in genetic screen for thiamin metabolic genes (PMID:15292217)	1.0	GFF3663		Putative inner membrane protein	0.46	12
Enterobacter sp. TBS_079	0.86	MPMX20_01037		HMP-PP phosphatase	0.81	MPMX20_01565		hypothetical protein	low	> 85
Escherichia coli BL21	0.84	ECD_00398		thiamine pyrimidine pyrophosphate hydrolase; HMP-PP phosphatase	0.87	ECD_00910		UPF0702 family putative inner membrane protein	low	> 60
Escherichia coli ECRC62	0.84	BNILDI_22635	cof	HMP-PP phosphatase	0.87	BNILDI_20310	ycaP	UPF0702 transmembrane protein YcaP	—	—
Escherichia coli ECOR27	0.84	NOLOHH_01220	cof	HMP-PP phosphatase	0.87	NOLOHH_22055	ycaP	UPF0702 transmembrane protein YcaP	low	> 57
Escherichia coli ECOR38	0.84	HEPCGN_06900	cof	HMP-PP phosphatase	0.87	HEPCGN_23025	ycaP	UPF0702 transmembrane protein YcaP	low	> 85
Escherichia coli HS(pFamp)R (ATCC 700891)	0.84	OHPLBJKB_03227		HMP-PP phosphatase	0.87	OHPLBJKB_02762		hypothetical protein	low	> 73
Escherichia fergusonii Becca	0.84	EFB2_03611		HMP-PP phosphatase	0.88	EFB2_03158		hypothetical protein	low	> 86
Escherichia coli ECRC101	0.84	MCAODC_27510	cof	HMP-PP phosphatase	0.87	MCAODC_24885	ycaP	UPF0702 transmembrane protein YcaP	—	—
Enterobacter asburiae PDN3	0.84	EX28DRAFT_2524		HAD-superfamily hydrolase, subfamily IIB	0.82	EX28DRAFT_2029		Predicted membrane protein	low	> 76
Escherichia coli ECRC101	0.84	OKFHMN_08285	cof	HMP-PP phosphatase	0.87	OKFHMN_05495	ycaP	UPF0702 transmembrane protein YcaP	—	—
Escherichia coli ECRC102	0.84	NIAGMN_06340	cof	HMP-PP phosphatase	0.87	NIAGMN_03215	ycaP	UPF0702 transmembrane protein YcaP	—	—
Escherichia coli ECRC99	0.84	KEDOAH_19680	cof	HMP-PP phosphatase	0.87	KEDOAH_22240	ycaP	UPF0702 transmembrane protein YcaP	—	—
Escherichia coli ECRC98	0.84	JDDGAC_11940	cof	HMP-PP phosphatase	0.87	JDDGAC_09105	ycaP	UPF0702 transmembrane protein YcaP	—	—
Escherichia coli Nissle 1917	0.84	ECOLIN_RS02670		HMP-PP phosphatase	0.88	ECOLIN_RS04800		DUF421 domain-containing protein	—	—
Escherichia coli BW25113	0.84	b0446	cof	orf, hypothetical protein (VIMSS)	0.87	b0906	ycaP	conserved inner membrane protein (NCBI)	low	> 76
Klebsiella michiganensis M5al	0.81	BWI76_RS06570		thiamin pyrimidine pyrophosphate hydrolase	0.81	BWI76_RS09750		DUF421 domain-containing protein	low	> 92
Pantoea sp. MT58	0.62	IAI47_14610		HMP-PP phosphatase	0.52	IAI47_14135		DUF421 domain-containing protein	low	> 76

Not shown: 4 genomes with orthologs for GFF4362 only; 5 genomes with orthologs for GFF3663 only