Conservation of cofitness between GFF4362 and GFF3279 in Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

13 genomes with putative orthologs of both genes

Organism	Ratio1	Gene1	Name1	Description1	Ratio2	Gene2	Name2	Description2	Cofit	Rank
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868	1.0	GFF4362		HMP-PP hydrolase (pyridoxal phosphatase) Cof, detected in genetic screen for thiamin metabolic genes (PMID:15292217)	1.0	GFF3279		5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase (EC 1.2.1.60)	0.47	10
Enterobacter sp. TBS_079	0.86	MPMX20_01037		HMP-PP phosphatase	0.98	MPMX20_00641		NAD/NADP-dependent betaine aldehyde dehydrogenase	low	> 85
Escherichia coli HS(pFamp)R (ATCC 700891)	0.84	OHPLBJKB_03227		HMP-PP phosphatase	0.99	OHPLBJKB_03711		NAD/NADP-dependent betaine aldehyde dehydrogenase	low	> 73
Escherichia coli ECOR27	0.84	NOLOHH_01220	cof	HMP-PP phosphatase	0.99	NOLOHH_03720	hpaE	5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase	low	> 57
Escherichia coli BL21	0.84	ECD_00398		thiamine pyrimidine pyrophosphate hydrolase; HMP-PP phosphatase	0.99	ECD_04229		5-carboxy-2-hydroxymuconate semialdehyde dehydrogenase	low	> 60
Escherichia coli ECRC62	0.84	BNILDI_22635	cof	HMP-PP phosphatase	0.99	BNILDI_07880	hpaE	5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase	—	—
Enterobacter asburiae PDN3	0.84	EX28DRAFT_2524		HAD-superfamily hydrolase, subfamily IIB	0.98	EX28DRAFT_3546		5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase	low	> 76
Escherichia coli BW25113	0.84	b0446	cof	orf, hypothetical protein (VIMSS)	0.35	b1300	puuC	gamma-Glu-gamma-aminobutyraldehyde dehydrogenase, NAD(P)H-dependent (NCBI)	low	> 76
Klebsiella michiganensis M5al	0.81	BWI76_RS06570		thiamin pyrimidine pyrophosphate hydrolase	0.98	BWI76_RS03865		5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase	low	> 92
Pantoea sp. MT58	0.62	IAI47_14610		HMP-PP phosphatase	0.35	IAI47_08650		betaine-aldehyde dehydrogenase	low	> 76
Serratia liquefaciens MT49	0.61	IAI46_05055		HMP-PP phosphatase	0.90	IAI46_02735		5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase	low	> 86
Rahnella sp. WP5	0.59	EX31_RS22290		HMP-PP phosphatase	0.35	EX31_RS18820		betaine-aldehyde dehydrogenase	low	> 89
Alteromonas macleodii MIT1002	0.12	MIT1002_01880		Pyridoxal phosphate phosphatase YigL	0.36	MIT1002_02095		2-hydroxymuconic semialdehyde dehydrogenase	low	> 70
Agrobacterium fabrum C58	0.10	Atu0660		hydrolase	0.34	Atu0829		betaine aldehyde dehydrogenase	low	> 89

Not shown: 8 genomes with orthologs for GFF4362 only; 44 genomes with orthologs for GFF3279 only