Conservation of cofitness between ECD_02885 and ECD_02586 in Escherichia coli BL21

12 genomes with putative orthologs of both genes

Organism	Ratio1	Gene1	Name1	Description1	Ratio2	Gene2	Name2	Description2	Cofit	Rank
Escherichia coli BL21	1.0	ECD_02885		2,5-diketo-D-gluconate reductase A	1.0	ECD_02586		putative dehydrogenase	0.34	50
Escherichia coli ECOR27	1.00	NOLOHH_10710	dkgA	2,5-didehydrogluconate reductase DkgA	1.00	NOLOHH_12355	ltnD	L-threonate dehydrogenase	low	> 75
Escherichia coli ECRC62	1.00	BNILDI_00805	dkgA	2,5-didehydrogluconate reductase DkgA	1.00	BNILDI_10905	ltnD	L-threonate dehydrogenase	low	> 75
Escherichia coli BW25113	1.00	b3012	yqhE	orf, hypothetical protein (VIMSS)	0.99	b2736	ygbJ	predicted dehydrogenase, with NAD(P)-binding Rossmann-fold domain (NCBI)	low	> 76
Escherichia coli HS(pFamp)R (ATCC 700891)	1.00	OHPLBJKB_00689		2,5-diketo-D-gluconic acid reductase A	1.00	OHPLBJKB_00997		L-threonate dehydrogenase	0.43	10
Escherichia fergusonii Becca	1.00	EFB2_00798		2,5-diketo-D-gluconic acid reductase A	0.98	EFB2_01176		L-threonate dehydrogenase	low	> 86
Escherichia coli Nissle 1917	0.99	ECOLIN_RS17340		2,5-didehydrogluconate reductase DkgA	0.98	ECOLIN_RS15290		L-threonate dehydrogenase	low	> 55
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868	0.90	GFF3125		Methylglyoxal reductase, acetol producing (EC 1.1.1.-) / 2,5-diketo-D-gluconate reductase A (EC 1.1.1.274)	0.77	GFF4782		D-beta-hydroxybutyrate dehydrogenase (EC 1.1.1.30)	low	> 78
Pantoea sp. MT58	0.75	IAI47_03200		2,5-didehydrogluconate reductase DkgA	0.70	IAI47_07140		NAD(P)-dependent oxidoreductase	low	> 76
Serratia liquefaciens MT49	0.74	IAI46_21755		2,5-didehydrogluconate reductase DkgA	0.71	IAI46_07605		NAD(P)-dependent oxidoreductase	low	> 86
Pectobacterium carotovorum WPP14	0.74	HER17_RS19715		2,5-didehydrogluconate reductase DkgA	0.70	HER17_RS00565		NAD(P)-dependent oxidoreductase	low	> 75
Paraburkholderia bryophila 376MFSha3.1	0.23	H281DRAFT_00358		Aldo/keto reductase	0.51	H281DRAFT_01510		3-hydroxyisobutyrate dehydrogenase	low	> 103
Burkholderia phytofirmans PsJN	0.22	BPHYT_RS08410		dehydrogenase	0.50	BPHYT_RS29415		3-hydroxyisobutyrate dehydrogenase	—	—

Not shown: 26 genomes with orthologs for ECD_02885 only; 18 genomes with orthologs for ECD_02586 only