Conservation of cofitness between b1827 and b3990 in Escherichia coli BW25113

22 genomes with putative orthologs of both genes

Organism	Ratio1	Gene1	Name1	Description1	Ratio2	Gene2	Name2	Description2	Cofit	Rank
Escherichia coli BW25113	1.0	b1827	kdgR	predicted DNA-binding transcriptional regulator (NCBI)	1.0	b3990	thiH	thiamine biosynthesis protein ThiH (NCBI)	0.26	11
Escherichia coli ECRC101	1.00	MCAODC_18925	kdgR	DNA-binding transcriptional regulator KdgR	0.99	MCAODC_03900	thiH	2-iminoacetate synthase ThiH	—	—
Escherichia coli HS(pFamp)R (ATCC 700891)	1.00	OHPLBJKB_01904		Transcriptional regulator KdgR	0.99	OHPLBJKB_04061		2-iminoacetate synthase	low	> 73
Escherichia coli ECRC102	1.00	NIAGMN_01580	kdgR	DNA-binding transcriptional regulator KdgR	0.99	NIAGMN_11150	thiH	2-iminoacetate synthase ThiH	—	—
Escherichia coli ECRC101	1.00	OKFHMN_26480	kdgR	DNA-binding transcriptional regulator KdgR	0.99	OKFHMN_13400	thiH	2-iminoacetate synthase ThiH	—	—
Escherichia coli BL21	1.00	ECD_01798		KDG regulon transcriptional repressor	0.99	ECD_03866		tyrosine lyase, involved in thiamine-thiazole moiety synthesis	low	> 60
Escherichia coli ECRC98	1.00	JDDGAC_01055	kdgR	DNA-binding transcriptional regulator KdgR	0.99	JDDGAC_17025	thiH	2-iminoacetate synthase ThiH	—	—
Escherichia coli ECRC99	1.00	KEDOAH_01625	kdgR	DNA-binding transcriptional regulator KdgR	0.99	KEDOAH_14760	thiH	2-iminoacetate synthase ThiH	—	—
Escherichia coli Nissle 1917	0.99	ECOLIN_RS10175		DNA-binding transcriptional regulator KdgR	0.97	ECOLIN_RS23015		2-iminoacetate synthase ThiH	—	—
Escherichia coli ECOR38	0.99	HEPCGN_04880	kdgR	DNA-binding transcriptional regulator KdgR	0.98	HEPCGN_12035	thiH	2-iminoacetate synthase ThiH	low	> 85
Escherichia fergusonii Becca	0.99	EFB2_02174		Transcriptional regulator KdgR	0.97	EFB2_04622		2-iminoacetate synthase	low	> 86
Escherichia coli ECRC62	0.99	BNILDI_15785	kdgR	DNA-binding transcriptional regulator KdgR	0.99	BNILDI_05980	thiH	2-iminoacetate synthase ThiH	—	—
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868	0.96	GFF2842		Transcriptional regulator KdgR, KDG operon repressor	0.91	GFF4203		Thiazole biosynthesis protein ThiH	low	> 78
Enterobacter sp. TBS_079	0.95	MPMX20_02734		Transcriptional regulator KdgR	0.90	MPMX20_00212		2-iminoacetate synthase	low	> 85
Klebsiella michiganensis M5al	0.95	BWI76_RS17960		DNA-binding transcriptional regulator KdgR	0.91	BWI76_RS01530		2-iminoacetate synthase ThiH	—	—
Enterobacter asburiae PDN3	0.95	EX28DRAFT_0729		transcriptional regulator, IclR family	0.90	EX28DRAFT_4531		thiazole biosynthesis protein ThiH	low	> 76
Dickeya dadantii 3937	0.91	DDA3937_RS11445		DNA-binding transcriptional regulator KdgR	0.80	DDA3937_RS01150		2-iminoacetate synthase ThiH	low	> 74
Dickeya dianthicola 67-19	0.90	HGI48_RS11490		DNA-binding transcriptional regulator KdgR	0.81	HGI48_RS01145		2-iminoacetate synthase ThiH	low	> 71
Dickeya dianthicola ME23	0.90	DZA65_RS11830		DNA-binding transcriptional regulator KdgR	0.81	DZA65_RS01190		2-iminoacetate synthase ThiH	low	> 75
Pectobacterium carotovorum WPP14	0.89	HER17_RS11535		DNA-binding transcriptional regulator KdgR	0.81	HER17_RS20405		2-iminoacetate synthase ThiH	low	> 75
Rahnella sp. WP5	0.85	EX31_RS24895		DNA-binding transcriptional regulator KdgR	0.77	EX31_RS16790		2-iminoacetate synthase ThiH	low	> 89
Serratia liquefaciens MT49	0.82	IAI46_10820		DNA-binding transcriptional regulator KdgR	0.79	IAI46_01295		2-iminoacetate synthase ThiH	low	> 86
Erwinia tracheiphila SCR3	0.80	LU632_RS13230	kdgR	DNA-binding transcriptional regulator KdgR	0.76	LU632_RS00945	thiH	2-iminoacetate synthase ThiH	low	> 74

Not shown: 33 genomes with orthologs for b1827 only; 18 genomes with orthologs for b3990 only