Conservation of cofitness between b0460 and b1285 in Escherichia coli BW25113

17 genomes with putative orthologs of both genes

Organism	Ratio1	Gene1	Name1	Description1	Ratio2	Gene2	Name2	Description2	Cofit	Rank
Escherichia coli BW25113	1.0	b0460	hha	modulator of gene expression, with H-NS (NCBI)	1.0	b1285	gmr	modulator of Rnase II stability (NCBI)	0.31	11
Escherichia coli ECRC62	1.00	BNILDI_22565	tomB	Hha toxicity modulator TomB	0.99	BNILDI_18340	pdeR	cyclic di-GMP phosphodiesterase	—	—
Escherichia coli ECRC99	1.00	KEDOAH_19750	tomB	Hha toxicity modulator TomB	0.99	KEDOAH_26240	pdeR	cyclic di-GMP phosphodiesterase	—	—
Escherichia coli ECRC98	1.00	JDDGAC_11870	tomB	Hha toxicity modulator TomB	0.99	JDDGAC_05070	pdeR	cyclic di-GMP phosphodiesterase	—	—
Escherichia coli HS(pFamp)R (ATCC 700891)	1.00	OHPLBJKB_03214		Hemolysin expression-modulating protein Hha	0.99	OHPLBJKB_02396		Cyclic di-GMP phosphodiesterase PdeR	low	> 73
Escherichia coli ECRC102	1.00	NIAGMN_06270	tomB	Hha toxicity modulator TomB	0.99	NIAGMN_26695	pdeR	cyclic di-GMP phosphodiesterase	—	—
Escherichia coli ECOR38	1.00	HEPCGN_06830	tomB	Hha toxicity modulator TomB	0.99	HEPCGN_25675	pdeR	cyclic di-GMP phosphodiesterase	low	> 85
Escherichia coli ECRC101	1.00	OKFHMN_08215	tomB	Hha toxicity modulator TomB	0.99	OKFHMN_02525	pdeR	cyclic di-GMP phosphodiesterase	—	—
Escherichia coli BL21	1.00	ECD_00411		modulator of gene expression, with H-NS	0.99	ECD_01262		cyclic-di-GMP phosphodiesterase; csgD regulator; modulator of RNase II stability	—	—
Escherichia coli ECOR27	1.00	NOLOHH_01150	tomB	Hha toxicity modulator TomB	1.00	NOLOHH_20190	pdeR	cyclic di-GMP phosphodiesterase	—	—
Escherichia fergusonii Becca	1.00	EFB2_03598		Hemolysin expression-modulating protein Hha	0.98	EFB2_02639		Cyclic di-GMP phosphodiesterase PdeR	low	> 86
Escherichia coli Nissle 1917	1.00	ECOLIN_RS02740		HHA domain-containing protein	0.98	ECOLIN_RS07755		cyclic di-GMP phosphodiesterase	—	—
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868	0.99	GFF4377		Haemolysin expression modulating protein	0.80	GFF2699		FIG00637999: hypothetical protein	—	—
Enterobacter asburiae PDN3	0.96	EX28DRAFT_2498		Haemolysin expression modulating protein	0.80	EX28DRAFT_0960		PAS domain S-box/diguanylate cyclase (GGDEF) domain	low	> 76
Enterobacter sp. TBS_079	0.96	MPMX20_01062		Hemolysin expression-modulating protein Hha	0.80	MPMX20_02488		Cyclic di-GMP phosphodiesterase PdeR	low	> 85
Pantoea sp. MT58	0.85	IAI47_14555		hemolysin expression modulator Hha	0.69	IAI47_09305		cyclic di-GMP phosphodiesterase	low	> 76
Serratia liquefaciens MT49	0.85	IAI46_05140		hemolysin expression modulator Hha	0.63	IAI46_24280		cyclic di-GMP phosphodiesterase	low	> 86
Rahnella sp. WP5	0.82	EX31_RS22430		hemolysin expression modulator Hha	0.58	EX31_RS08335		cyclic di-GMP phosphodiesterase	low	> 89

Not shown: 7 genomes with orthologs for b0460 only; 4 genomes with orthologs for b1285 only