Pairwise Alignments
Query, 1298 a.a., Phosphoribosylformylglycinamidine synthase, synthetase subunit (EC 6.3.5.3) / Phosphoribosylformylglycinamidine synthase, glutamine amidotransferase subunit (EC 6.3.5.3) from Pseudomonas fluorescens FW300-N1B4
Subject, 754 a.a., Phosphoribosylformylglycinamidine synthase II PurL (FGAM synthase II) from Mycobacterium tuberculosis H37Rv
Score = 170 bits (431), Expect = 4e-46
Identities = 197/756 (26%), Positives = 319/756 (42%), Gaps = 115/756 (15%)
Query: 195 LKRNPHDIELMMFAQANSEHCRHKIFNASWDIDGQSQEKSLFGMIKNTYQMHSEGVLSAY 254
L R P D EL M++ SEHC +K G++ + +L+
Sbjct: 35 LGRRPTDTELAMYSVMWSEHCSYKSSKVHLRYFGETTSDEM-----------RAAMLAGI 83
Query: 255 KDNASVIVGSVAGRFFPDPETRQYGAVQEPVHILMKVETHNHPTAIAPFPGASTGSGGEI 314
+NA V+ + + + KVE+HNHP+ + P+ GA+TG GG +
Sbjct: 84 GENAGVV------------------DIGDGWAVTFKVESHNHPSYVEPYQGAATGVGGIV 125
Query: 315 RDEGATGRGAKPKAGLTGFTVSNLQIPGFEQPWEVPYGKPERIVTALDIMIEGPLGGAAF 374
RD A G A+P A + P + LD ++ G +GG +
Sbjct: 126 RDIMAMG--ARPVAVMDQLRFGAADAPDTRR--------------VLDGVVRG-IGG--Y 166
Query: 375 NNEFGRPALTGYFRTFEQSITTP--RGDEVRGYHKPIMLAGGMGNIRAEHVQKGEIT-VG 431
N G P + G +++ P G+ P++ A +G +R E + + G
Sbjct: 167 GNSLGLPNIGG------ETVFDPCYAGN-------PLVNALCVGVLRQEDLHLAFASGAG 213
Query: 432 SKLIVLGGPAMLIGLGGGAASSMATGTSSAD---LDFASVQRENPEMERRCQEVIDRCWQ 488
+K+I+ G L G+GG S +A+ T A+ SVQ +P ME+ +I+ C +
Sbjct: 214 NKIILFGARTGLDGIGG--VSVLASDTFDAEGSRKKLPSVQVGDPFMEK---VLIECCLE 268
Query: 489 LGDKNPISFIHDVGAGGLSNAFPELVNDGNRGGRFELRNIPNDEPGMAPHEIWSNESQER 548
L + I D+G GLS A EL + G+ G +L ++P M P E+ +ESQER
Sbjct: 269 LYAGGLVIGIQDLGGAGLSCATSELASAGDGGMTIQLDSVPLRAKEMTPAEVLCSESQER 328
Query: 549 YVLAVGPADFERFQAICERERCPFAVVGEATAEPQLTVTDSHFGNSPVDMPLEVLLGKAP 608
V P + + F A+C + V+GE T +L +T G + VD+P + + P
Sbjct: 329 MCAVVSPKNVDAFLAVCRKWEVLATVIGEVTDGDRLQIT--WHGETVVDVPPRTVAHEGP 386
Query: 609 RMHRSAVR---ENELGDDFDPSTL------EIADCVERVLHHPAVASKSFLITIGDRTIT 659
R R ++ L D E+ + +L P + S++F+ DR +
Sbjct: 387 VYQRPVARPDTQDALNADRSAKLSRPVTGDELRATLLALLGSPHLCSRAFITEQYDRYVR 446
Query: 660 GLVARDQMVGPWQVPVADVAVTATSFDVYTGEAMAMGERTPLALLDAPASGRMAIGETLT 719
G + AD + G A++ LLD A ++A+ E
Sbjct: 447 GNTVLAEH--------ADGGMLRIDESTGRGIAVSTDASGRYTLLDPYAGAQLALAEAYR 498
Query: 720 NIAASRIAKISDIKLSANWMSAAGHPGEDARLYDTVKAVG--MELCPDLGITIPVGKDSM 777
N+A + ++ + N+ G P + ++ +AV + C DLGI + G S
Sbjct: 499 NVAVTGATPVA-VTNCLNF----GSPEDPGVMWQFTQAVRGLADGCADLGIPVTGGNVSF 553
Query: 778 SMATRWNDEGVDKTVTSPMSLIVTGFAPVADIRQTMTPQLRMDKGTTDLILIDLGRGQNR 837
+N G + +P +V + D+R+ + L + G T L+ LG ++
Sbjct: 554 -----YNQTGSAAILPTP---VVGVLGVIDDVRRRIPTGLGAEPGET---LMLLGDTRDE 602
Query: 838 MGASILAQVHG-KLGKQAPDVDDAEDLKAFFAVIQGLNADGHLLAYHDRSDGGLLTSVVE 896
S+ AQV LG P VD A + K AV+ + DG + A HD S+GGL ++VE
Sbjct: 603 FDGSVWAQVTADHLGGLPPVVDLARE-KLLAAVLSSASRDGLVSAAHDLSEGGLAQAIVE 661
Query: 897 MAFAGHCGLSLNLDGLAETSADIAAILFNEELGAVI 932
A AG G + L AD +LF+E G V+
Sbjct: 662 SALAGETGCRIVL----PEGADPFVLLFSESAGRVL 693
Score = 37.7 bits (86), Expect = 4e-06
Identities = 25/82 (30%), Positives = 36/82 (43%), Gaps = 6/82 (7%)
Query: 495 ISFIHDVGAGGLSNAFPELVNDGNRGGRFELRNIPNDEPGMAPHEIWSNESQERYVLAVG 554
+S HD+ GGL+ A E G G R L G P + +ES R ++AV
Sbjct: 644 VSAAHDLSEGGLAQAIVESALAGETGCRIVLPE------GADPFVLLFSESAGRVLVAVP 697
Query: 555 PADFERFQAICERERCPFAVVG 576
+ RF+ +CE P +G
Sbjct: 698 RTEESRFRGMCEARGLPAVRIG 719
Score = 35.0 bits (79), Expect = 3e-05
Identities = 28/112 (25%), Positives = 52/112 (46%), Gaps = 11/112 (9%)
Query: 873 LNADGHLLAYHDRSDGGLLTSVVEMAFAGHCGLSLNLDGLA-----ETSADIAAILFNEE 927
L A G ++ D GL + E+A AG G+++ LD + T A++ E
Sbjct: 269 LYAGGLVIGIQDLGGAGLSCATSELASAGDGGMTIQLDSVPLRAKEMTPAEVLCSESQER 328
Query: 928 LGAVIQVRQ-DATPDILAQFSAAGLGDCVSVIGQPMNNGEISITFNGDTVFE 978
+ AV+ + DA + ++ +VIG+ + + IT++G+TV +
Sbjct: 329 MCAVVSPKNVDAFLAVCRKWEVLA-----TVIGEVTDGDRLQITWHGETVVD 375