Pairwise Alignments

Query, 702 a.a., (p)ppGpp synthetase, RelA/SpoT family from Pseudomonas stutzeri RCH2

Subject, 705 a.a., bifunctional GTP diphosphokinase/guanosine-3',5'-bis(diphosphate) 3'-diphosphatase from Vibrio cholerae E7946 ATCC 55056

 Score =  775 bits (2000), Expect = 0.0
 Identities = 383/706 (54%), Positives = 512/706 (72%), Gaps = 7/706 (0%)

Query: 1   MPAIDALADRLSTYLGPDQVNLVRRAYFYAEQAHDGQRRRSGEAYVTHPLAVANILADMH 60
           M   D+L D    YL   Q+  +R++Y  A  AH+GQ R SGE Y+ HP+AVA ILA+M 
Sbjct: 1   MYLFDSLKDVAQEYLTEPQIEALRQSYVVARDAHEGQTRSSGEPYIIHPVAVARILAEMR 60

Query: 61  MDHQSLMAAMLHDVIEDTGIPKEALVAQFGETVAELVDGVSKLTQMNFETKAEAQAENFQ 120
           +D ++L AA+LHDVIED  + KE L A FG +VAELVDGVSKL ++ F  + EAQAENF+
Sbjct: 61  LDLETLQAALLHDVIEDCDVTKEDLDAHFGSSVAELVDGVSKLDKLKFRDRKEAQAENFR 120

Query: 121 KMAMAMARDIRVILVKLADRLHNMRTLEVLAGEKRRRIAKETLEIYAPIANRLGMHTMRV 180
           KM +AM +DIRVIL+KLADR HNMRTL  L  +K+RRIA+ETLEIYAP+A+RLG+H ++ 
Sbjct: 121 KMVLAMVQDIRVILIKLADRTHNMRTLGALRPDKKRRIARETLEIYAPLAHRLGIHNIKT 180

Query: 181 EFEDLGFKAMHPMRSERIRAAVRRARGNRNEIVEKIEQSLIHCLEREGLDGEVLGREKHL 240
           E E+LGF+A++P R   ++  V+ ARGNR E++++I   +   L+  GL   V+GREK+L
Sbjct: 181 ELEELGFEALYPNRYRVLKEVVKAARGNRKEMIQRIHSEIEGRLQEVGLPARVVGREKNL 240

Query: 241 YSIYKKMRGKRKAFHEIMDVYAFRIVVDKADTCYRVLGAVHSLYKPLPGRFKDYIAIPKA 300
           +SIY KM+ K + FH IMD+YAFRIVVD ADTCYRVLG VHSLYKP P R KDYIA+PKA
Sbjct: 241 FSIYNKMKTKEQRFHTIMDIYAFRIVVDTADTCYRVLGQVHSLYKPRPARMKDYIAVPKA 300

Query: 301 NGYQSLHTTLFGMHGVPIEIQIRTREMEEMANNGIAAHWLYKSPEDEVPKGTHARARQWV 360
           NGYQSLHT++ G HGVP+E+QIRT +M++MA+ G+AAHW YK+  +        +A++W+
Sbjct: 301 NGYQSLHTSMVGPHGVPVEVQIRTEDMDQMADKGVAAHWSYKANSERGGTTAQIKAQRWM 360

Query: 361 KGVLELQQRAGNSLEFIESVKIDLFPDEVYVFTPKGRIMEMPKGSTAVDFAYAVHTDVGN 420
           + +LELQQ AGNS EFIE+VK DLFPDE+YVFTPKGRI+E+P G+TAVDFAYAVHTD+GN
Sbjct: 361 QSLLELQQSAGNSFEFIENVKSDLFPDEIYVFTPKGRIVELPMGATAVDFAYAVHTDIGN 420

Query: 421 TCIACRVNRRLAPLSQPLESGSTVEIVTAPGARPNPAWLNFVVTGKARTHIRHALKLQRR 480
           TC+  RV+R   PLSQ L+SG TVEI++APGARPN AWLN+VVT +ART IR  LK  RR
Sbjct: 421 TCVGARVDRTPYPLSQSLKSGQTVEIISAPGARPNAAWLNYVVTSRARTKIRQVLKTMRR 480

Query: 481 SESINLGERLLSKALSGFETSLEKISPERIQQVLTEYHMEYVEDLLEDIGLGNRMAYVIA 540
            +SI LG RLL+ AL   E S+ +I+PE I +VL++  +  ++DLL  IGLG  M+ VIA
Sbjct: 481 EDSITLGRRLLNHALG--EHSVNEIAPENISKVLSDLKIASMDDLLAAIGLGELMSIVIA 538

Query: 541 RRLILRDDE-QAPALEG----PLAIRGTEGLVLNYAKCCTPIPGDPIVGHLSAGKGMVVH 595
           RRL+   DE   P+  G     L IRG EG++L +A CC PIP D I+ H+S G+G+VVH
Sbjct: 539 RRLLGNADELTEPSKSGGNKNKLPIRGAEGILLTFANCCHPIPDDHIIAHVSPGRGLVVH 598

Query: 596 LETCRNIADVRHNPDKCIQLSWSKDVTGEFNVELRVELEHQRGLIALLAGSVNAADGNIE 655
            ETC N+   +  PDK + + W+KD   EF  EL+V++ +++G +A L   ++    NI 
Sbjct: 599 RETCPNVRGYQKEPDKYMAVEWTKDYDQEFITELKVDMHNRQGALAELTNVISKTGSNIH 658

Query: 656 KIGMDERDGRISVVQLVVSVHDRVHLARVIKKLRAIKGVTRITRVK 701
            +  +ERDGR+  V ++++  DRVHLA +++K+R +    ++ R K
Sbjct: 659 GLSTEERDGRLYTVTVLLTTKDRVHLAGIMRKIRTMPHALKVRRRK 704